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alpha-Aminoisobutyric acid methyl ester hydrochloride

alpha-Aminoisobutyric acid methyl ester hydrochloride structure

CAS No.: 15028-41-8

Chemical Name:: alpha-Aminoisobutyric acid methyl ester hydrochloride

Synonyms: Aib.ome.HCL;H-Aib-OMe;H-Aib-OMe.HCI;alpha-Aminoi;Methyl αL-Aib-OMe·HCl;H-AIB-OME HCL;2-Aib-Ome.Hcl;H-ALA(ME)-OME HCL;H-a-Me-Ala-OMe · HCl

CBNumber:: CB8730255

Molecular Formula:: C5H12ClNO2

Molecular Weight:: 153.61

MDL Number:: MFCD00214247

MOL File:: 15028-41-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:55:52

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alpha-Aminoisobutyric acid methyl ester hydrochloride Properties

Melting point	185°C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Sparingly), Methanol (Slightly), Water (Slightly)
form	Crystalline Powder
color	White
Water Solubility	Slightly soluble in water.
InChI	InChI=1S/C5H11NO2.ClH/c1-5(2,6)4(7)8-3;/h6H2,1-3H3;1H
InChIKey	NVWZNEDLYYLQJC-UHFFFAOYSA-N
SMILES	C(N)(C)(C)C(=O)OC.Cl
CAS DataBase Reference	15028-41-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07,GHS09

Signal word

Danger

Hazard statements

H302+H312-H315-H318-H411

Precautionary statements

P273-P280-P301+P312+P330-P302+P352+P312-P305+P351+P338+P310

Safety Statements

24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29224999

NFPA 704

	1
2		1

alpha-Aminoisobutyric acid methyl ester hydrochloride price More Price(87)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M2406	Methyl 2-Amino-2-methylpropanoate Hydrochloride	15028-41-8	1G	$54	2026-04-30	Buy
Usbiological	260805	-alpha-Aminoisobutyric acid methyl ester hydrochloride Asreported	15028-41-8	2g	$353	2026-06-03	Buy
Usbiological	260805	-alpha-Aminoisobutyric acid methyl ester hydrochloride Asreported	15028-41-8	5g	$509	2026-06-03	Buy
Usbiological	260805	-alpha-Aminoisobutyric acid methyl ester hydrochloride Asreported	15028-41-8	10g	$695	2026-06-03	Buy
Usbiological	260805	-alpha-Aminoisobutyric acid methyl ester hydrochloride Asreported	15028-41-8	25g	$855	2026-06-03	Buy

Product number	Packaging	Price	Buy
M2406	1G	$54	Buy
260805	2g	$353	Buy
260805	5g	$509	Buy
260805	10g	$695	Buy
260805	25g	$855	Buy

alpha-Aminoisobutyric acid methyl ester hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

Methyl α-aminoisobutyrate is used as a specific substrate of amino acid transport system and in studies on amino acid transport systems.

Synthesis

67-56-1

62-57-7

ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE

15028-41-8

1. 2-Amino-2-methylpropionic acid (10 g, 96.9 mmol) and methanol (330 ml) were added to a reaction vial. 2. The reaction vial was placed in an ice bath and thionyl chloride (17.68 ml, 242.25 mmol) was slowly added dropwise. 3. After the dropwise addition was completed, the ice bath was removed and the reaction mixture was stirred at room temperature for 3 hours. 4. After completion of the reaction, the solvent was removed by vacuum distillation. 5. The residue was dried in an oven at 60 °C to give methyl 2-amino-2-methylpropionate hydrochloride as a white solid (14.59 g, 94.9 mmol, 98% yield). 6. The product was analyzed by 1H NMR. 6. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 8.75 (br, 3H), 3.75 (s, 3H), 1.45 (s, 6H).

References

[1] Organic Letters, 2012, vol. 14, # 18, p. 4798 - 4801
[2] European Journal of Organic Chemistry, 2004, # 20, p. 4167 - 4176
[3] Patent: WO2013/19091, 2013, A2. Location in patent: Paragraph 936-938
[4] Patent: US2014/206875, 2014, A1. Location in patent: Paragraph 0513-0514; 0568-0569; 0599-0600; 0658-0660
[5] Tetrahedron, 1982, vol. 38, # 14, p. 2165 - 2182

alpha-Aminoisobutyric acid methyl ester hydrochloride synthesis

Synthesis of alpha-Aminoisobutyric acid methyl ester hydrochloride from 2-Aminoisobutyric Acid

alpha-Aminoisobutyric acid methyl ester hydrochloride Preparation Products And Raw materials

Raw materials

2-Amino-2-methylpropanoyl chloride Aminoisobutyric acid hydrochloride N - (tert - butoxycarbonyl) - ± - Methylalanine Methyl ester Methanol Iodomethane

2-Aminoisobutyric Acid Chlorotrimethylsilane

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Preparation Products

Propanamide, 2-amino-N-[2-(dimethylamino)ethyl]-2-methyl- Alanine, 2-methyl-N-(phenylmethyl)-, methyl ester Methyl 2-(benzyloxycarbonylamino)-2-methylpropanoate

alpha-Aminoisobutyric acid methyl ester hydrochloride Suppliers

Global( 262)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
YangZhou Ruihong Biotech Co., Ltd.	0514-015380367604 15380367604	sales@ruibobiotech.com	China	509	55
Taizhou Tianhong Biochemistry Technology Co., Ltd.	0523-86132544 15366717810	sales@thbiochem.com	China	407	55
Sichuan HongRi Pharma-Tech Co., Ltd	1898-2685405 18380436509	2065506070@qq.com	China	1930	58
Zhangjiagang Specom Biochemical Co., Ltd.	512-0512-58992291,58992287 18606280718	admin@spbiochem.com	China	306	62
HANGZHOU LOOP BIOTECH CO., LTD.	057185260761 13396556070	sales@looppharm.com	China	56	58
Nanjing Danron Bio-New Materials Co.Ltd	18936428028 18936428028	3806853067@qq.com	China	147	58
Awesome （Beijing）TechnologyCo.,Ltd.	18201687790 18201687790	yunbo12291229@163.com	China	137	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84

Supplier	Advantage
YangZhou Ruihong Biotech Co., Ltd.	55
Taizhou Tianhong Biochemistry Technology Co., Ltd.	55
Sichuan HongRi Pharma-Tech Co., Ltd	58
Zhangjiagang Specom Biochemical Co., Ltd.	62
HANGZHOU LOOP BIOTECH CO., LTD.	58
Nanjing Danron Bio-New Materials Co.Ltd	58
Awesome （Beijing）TechnologyCo.,Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84

View Lastest Price from alpha-Aminoisobutyric acid methyl ester hydrochloride manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-11	2-Aib-Ome.Hcl 15028-41-8	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-09-11	H-ALPHA-ME-ALA-OME HCL 15028-41-8	1KG	99%min	500kg	WUHAN FORTUNA CHEMICAL CO., LTD
2026-06-30	ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE 15028-41-8	1kg	98%	1000kg	Shaanxi Dideu New Materials Co. Ltd

2-Aib-Ome.Hcl
15028-41-8
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

H-ALPHA-ME-ALA-OME HCL
15028-41-8
$0.00
99%min
WUHAN FORTUNA CHEMICAL CO., LTD

ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE
15028-41-8
98%
Shaanxi Dideu New Materials Co. Ltd

alpha-Aminoisobutyric acid methyl ester hydrochloride Spectrum

ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE(15028-41-8)¹HNMR ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE(15028-41-8)FT-IR

15028-41-8(alpha-Aminoisobutyric acid methyl ester hydrochloride)Related Search:

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2-Aminoisobutyric acid methyl ester hydrochloride, >=99% L-Aib-OMe·HCl -aminoisobutyrate hydrochloride Methyl 2-amino-2-methylpropanoate HCl METHYL 2-AMINOISOBUTYRATE HCL Methyleα-aminoisobutyrate hydrochloride Alpha-aminoisobutyric acid methyl ester, HCl ALPHA-AMINO-2-METHYLBUTYRIC ACID METHYL ESTER HYDROCHLORIDE 2-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE 2-METHYLALANINE METHYL ESTER HYDROCHLORIDE 2,2-DIMETHYLGLYCINE METHYL ESTER HYDROCHLORIDE Alpha-aminoisobutyric acid methyl ester, HCI Methyl 2-aminoisobutanoate hydrochloride H-AIB-OME HCL H-ALA(ME)-OME HCL H-ALPHA-ME-ALA-OME HCL A-aminoisobutyric acid methyl ester*hydrochloride methyl α-aminoisobutyrate hydrochloride α-aminoisobutyric acid methyl ester hydrochloride METHYL ALPHA-AMINOISOBUTYRATE HYDROCHLORIDE 2-AMINOISOBUTYRIC ACID METHYL ESTER HYDROCHLORIDE 98% 2-Aminoisobutyric acid methyl ester hydrochloride, 2-Methylalanine methyl ester hydrochloride, alpha-Amino-2-methylbutyric acid methyl ester hydrochloride, 2,2-Dimethylglycine methylester hydrochloride H-a-Me-Ala-OMe · HCl A-AMINOISOBUTYRICACIDMETHYLESTERHYDRO Methyl 2-amino-2-methylpropanoate hydrochloride REF DUPL: H-Aib-OMe HCl Methyl 2-Aminoisobutyrate Hydrochloride Methyl 2-methylalaninate hydrochloride H-Aib-OMe·HCl(α-AMinoisobutyric acid Methyl ester) alpha-Aminoi (1-methoxy-2-methyl-1-oxo-propan-2-yl)azanium chloride (1-methoxy-2-methyl-1-oxopropan-2-yl)azanium chloride (2-keto-2-methoxy-1,1-dimethyl-ethyl)ammonium chloride (2-methoxy-1,1-dimethyl-2-oxoethyl)ammonium chloride (2-methoxy-1,1-dimethyl-2-oxo-ethyl)ammonium chloride 2-amino-2-methylpropanoic acid methyl ester hydrochloride 2-amino-2-methyl-propionic acid methyl ester hydrochloride Alpha-aminoisobutyric acid methyl ester HCl, tech grade 2-Aib-Ome.Hcl ALPHA-AMINOISOBUTYRIC ACID METHYL ESTER HYDROC Methyl α Methyl α-aminoisobutyrate hydrochloride A-aminoisobutyric acid methyl Aib.ome.HCL H-Aib-OMe H-Aib-OMe.HCI Semaglutide Impurity 21 HCl (2E)-Diethyl fumarate alpha-Aminoisobutyric acid methyl ester hydrochloride 15028-41-8 28-41-8 15208-41-8 I - Z Modified Amino Acids Amino Acids and Peptides Biochemicals and Reagents BioChemical Pharmaceutical intermediate