ChemicalBook >> CAS DataBase List >>Methyl 2-chloroacetoacetate
Methyl 2-chloroacetoacetate
- CAS No.
- 4755-81-1
- Chemical Name:
- Methyl 2-chloroacetoacetate
- Synonyms
- Methyl 2-chloro-3-oxobutanoate;Apixaban Impurity 210;2-chloro acetylacetate;METHYL 2-CHLOROACETOACETATE;Methyle2-chloroacetoacetate;METHYL 2-CHLORO-3-OXOBUTANATE;Methyl 2-chloroacetoacetate,95%;Methyl 2-Chloroacetoacetate >methyl alpha-chloroacetoacetate;Chloroacetoaceticacidmethylester
- CBNumber:
- CB8737542
- Molecular Formula:
- C5H7ClO3
- Molecular Weight:
- 150.56
- MDL Number:
- MFCD00008757
- MOL File:
- 4755-81-1.mol
- MSDS File:
- SDS
Last updated:2026-09-04 08:02:39
| Melting point | -33--32.7 °C (lit.) |
|---|---|
| Boiling point | 137 °C (lit.) |
| Density | 1.236 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 161 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Liquid |
| pka | 7.89±0.46(Predicted) |
| color | Clear yellow |
| Water Solubility | 50 g/L (20 ºC) |
| Henry's Law Constant | 2.3×100 mol/(m3Pa) at 25℃, Ebert et al. (2023) |
| InChI | 1S/C5H7ClO3/c1-3(7)4(6)5(8)9-2/h4H,1-2H3 |
| InChIKey | GYQRIAVRKLRQKP-UHFFFAOYSA-N |
| SMILES | COC(=O)C(Cl)C(C)=O |
| CAS DataBase Reference | 4755-81-1(CAS DataBase Reference) |
| FDA UNII | 09T3687932 |
| NIST Chemistry Reference | Butanoic acid, 2-chloro-3-oxo-, methyl ester(4755-81-1) |
| EPA Substance Registry System | Methyl 2-chloroacetoacetate (4755-81-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-22 | |||||||||
| Safety Statements | 26-27-28-36/37/39-37/39 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29183000 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Methyl 2-chloroacetoacetate price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 183911 | Methyl 2-chloroacetoacetate | 4755-81-1 | 25g | $198 | 2023-06-20 | Buy |
| TCI Chemical | C1219 | Methyl 2-Chloroacetoacetate >95.0%(GC) | 4755-81-1 | 25g | $58 | 2026-04-30 | Buy |
| TCI Chemical | C1219 | Methyl 2-Chloroacetoacetate >95.0%(GC) | 4755-81-1 | 250g | $325 | 2026-04-30 | Buy |
| TRC | TRC-M295562-5G | Methyl 2-Chloroacetoacetate | 4755-81-1 | 5g | $76 | 2026-06-03 | Buy |
| TRC | TRC-M295562-25G | Methyl 2-Chloroacetoacetate | 4755-81-1 | 25g | $220 | 2026-06-03 | Buy |
Methyl 2-chloroacetoacetate Chemical Properties, Uses, Production
Chemical Properties
CLEAR YELLOW LIQUID
Uses
Methyl 2-chloroacetoacetate was used in one-pot synthesis of 2-arylimidazole-4-carboxylic acids. It was also used in synthesis of 3,5-disubstituted 1,2,4-triazoles.
Synthesis Reference(s)
Synthesis, p. 188, 1987 DOI: 10.1055/s-1987-27886
Methyl 2-chloroacetoacetate Preparation Products And Raw materials
Global Suppliers ( 163)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Beijing Donghualituo Techonlogy Development Co.,Ltd. | 010-88425576 | sales@dhltchem.com | China | 793 | 59 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 |
View Latest Price from Methyl 2-chloroacetoacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-03 | Methyl 2-chloroacetoacetate
4755-81-1
|
200KG | 98.0% | 20 T | Taixing Foreign Trade Nanjing Co., Ltd. | ||
 |
2026-08-07 | Methyl 2-Chloroacetoacetate
4755-81-1
|
$1.00-1.50 | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-05-28 | Methyl 2-Chloroacetoacetate
4755-81-1
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- Methyl 2-chloroacetoacetate
4755-81-1
- $0.00
- 98.0%
- Taixing Foreign Trade Nanjing Co., Ltd.
-
- Methyl 2-Chloroacetoacetate
4755-81-1
- $1.00-1.50
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Methyl 2-Chloroacetoacetate
4755-81-1
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
4755-81-1 (Methyl 2-chloroacetoacetate) Related Search:
2-chloro-3-oxo-butanoicacimethylester
Chloroacetoaceticacidmethylester
Butanoic acid, 2-chloro-3-oxo-, methyl ester
2-chloro-3-oxo-butyric acid methyl ester
2-Acetyl-2-chloroacetic acid methyl ester
Methyl 2-chloroacetoacetate,95%
2-chloro acetylacetate
2-CHLOROACETOACETIC ACID METHYL ESTER
2-chloro-3-oxobutanoic acid, methyl ester
METHYL 2-CHLORO-3-OXOBUTANATE
METHYL 2-CHLOROACETOACETATE
Methyle2-chloroacetoacetate
(2S)-2-chloro-3-oxobutanoic acid methyl ester
Methyl 2-Chloroacetoacetate >
Apixaban Impurity 210
methyl alpha-chloroacetoacetate
2-Chloroacetoacetate methyl ester
Methyl 2-chloro-3-oxobutanoate
4755-81-1
4775-81-1
CH3COCHClCO2CH3
Building Blocks
Carbonyl Compounds
C2 to C5
Organic Building Blocks
Esters
Building Blocks
C2 to C5
Carbonyl Compounds
Chemical Synthesis
Organic Building Blocks
C2 to C5
Carbonyl Compounds
Esters
