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Fluorescamine

Fluorescamine structure

CAS No.: 38183-12-9

Chemical Name:: Fluorescamine

Synonyms: FLURAM;Fluaram;FLURAM(R);RO 20-7234;Fluorescamin;FLUORESCAMINE;FluorescamineA.R.;Fluorescamine, pure;FLURAMANALYTICAL GRADE;Fluorescamine Labeling

CBNumber:: CB8755458

Molecular Formula:: C17H10O4

Molecular Weight:: 278.26

MDL Number:: MFCD00005928

MOL File:: 38183-12-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

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Fluorescamine Properties

Melting point	153-157 °C (lit.)
Boiling point	381.08°C (rough estimate)
Density	1.2661 (rough estimate)
refractive index	1.5447 (estimate)
Flash point	-17 °C
storage temp.	room temp
solubility	acetonitrile: soluble
form	powder
color	off-white to yellow
Water Solubility	Soluble in acetone, ethanol, chloroform, dimethylsulfoxide and acetonitrile. Slightly soluble in water.
Merck	14,4158
BRN	921143
Stability	Stable. Incompatible with strong oxidizing agents.
InChI	1S/C17H10O4/c18-15-13(11-6-2-1-3-7-11)10-20-17(15)14-9-5-4-8-12(14)16(19)21-17/h1-10H
InChIKey	ZFKJVJIDPQDDFY-UHFFFAOYSA-N
SMILES	O=C1OC2(OC=C(C2=O)c3ccccc3)c4ccccc14
CAS DataBase Reference	38183-12-9(CAS DataBase Reference)
FDA UNII	Y6859V58YW
NIST Chemistry Reference	Spiro[furan-2(3h),1'(3'h)-isobenzofuran]-3,3'-dione, 4-phenyl-(38183-12-9)
UNSPSC Code	12352204
NACRES	NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P280-P302+P352-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

F,Xi

Risk Statements

11-36/38-66-67-36-36/37/38

Safety Statements

22-24/25-36/37-33-29-26-16-9-37/39

RIDADR

UN 1090 3/PG 2

WGK Germany

10-21

HS Code

29322090

Storage Class

13 - Non Combustible Solids

NFPA 704

	1
2		0

Fluorescamine price More Price(70)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	F0192	Fluorescamine [for HPLC Labeling]	38183-12-9	100mg	$55	2026-04-30	Buy
TCI Chemical	F0192	Fluorescamine [for HPLC Labeling]	38183-12-9	1g	$394	2026-04-30	Buy
Cayman Chemical	34286	Fluorescamine ≥95%	38183-12-9	25mg	$36	2026-04-30	Buy
Cayman Chemical	34286	Fluorescamine ≥95%	38183-12-9	50mg	$53	2026-04-30	Buy
Cayman Chemical	34286	Fluorescamine ≥95%	38183-12-9	100mg	$75	2026-04-30	Buy

Product number	Packaging	Price	Buy
F0192	100mg	$55	Buy
F0192	1g	$394	Buy
34286	25mg	$36	Buy
34286	50mg	$53	Buy
34286	100mg	$75	Buy

Fluorescamine Chemical Properties,Uses,Production

Chemical Properties

white powder

Uses

Fluorescamine is a non-fluorescent reagent that reacts readily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Reaction takes place under mild conditions. Low background due to hydrolysis.

Uses

Analytical reagent.

Uses

For fluorescent detection of amino acids, peptides and proteins.Fluorescamine plays an important role as a reagent for the detection of amines, peptides and proteins. It is also used as a substrate for measuring protease activity. It is utilized in the detection and quantitation of residual aminopenicillins and sulfonamides in honey by HPLC. It finds application in the determination of lisinopril in human plasma and urine.

Synthesis Reference(s)

Journal of the American Chemical Society, 94, p. 5927, 1972 DOI: 10.1021/ja00771a084

Purification Methods

Fluram is a non-fluorescent reagent that reacts with primary amines to form highly fluorescent compounds. Purify it by dissolving (~1g) in Et2O/*C6H6 (1:1, 180 mL), washing with 1% aqueous NaHCO3 (50mL), drying (Na2SO4), and evaporating in a vacuum. Dissolve the residue in warm CH2Cl2 (5mL), dilute with Et2O (12mL) and refrigerate. Collect the solid and dry it in a vacuum. IR (CHCl3): 1810, 1745, 1722, 1625 and 1600 cm-1, and 1HNMR (CDCl3): 8.71 (s, -OHC=). [Weigele et max al. J Am Chem Soc 94 5927 1972, Weigele et al. J Org Chem 41 388 1976, Lai Methods Enzymol 47 236 1977.] Forskolin (Colforsin, Coleonol, 5-[acetyloxy]-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7, 10a-penta-methyl-[3R -{3

Fluorescamine Preparation Products And Raw materials

Raw materials

Ethanol Diethyl phthalate Tris(dimethylamino)methane Piperidine Hydrogen peroxide

Sodium Chloroform Aluminum chloride Benzaldehyde Diethyl ether

Benzene Hydrochloric acid Bromine Methanol Sodium hydroxide

N,N-Dimethylformamide dimethyl acetal Ammonium acetate Benzoic acid Dimethylamine 2-Acetylbenzoic acid

Malonic acid

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Preparation Products

Fluorescamine Suppliers

Global( 294)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Jianuokang Pharmaceutical Co., Ltd.	0519-85202684; 13775120798	jnkpharmtech@163.com	China	284	55
Beijing Ackerman Technology Co., Ltd.	18001219251	1406114168@qq.com	China	500	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Beijing HwrkChemical Technology Co., Ltd	89508211 18501085097	sales.bj@hwrkchemical.com	China	9407	55
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Beijing Ouhe Technology Co., Ltd	13552068683 13522913783	2355560935@qq.com	China	11777	60
Nanjing Search Biotech Co., Ltd	+86-025-81682922 +86-13515111588	sales@searchbio.com.cn	China	137	68

Supplier	Advantage
Changzhou Jianuokang Pharmaceutical Co., Ltd.	55
Beijing Ackerman Technology Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Beijing HwrkChemical Technology Co., Ltd	55
Energy Chemical	61
Beijing Ouhe Technology Co., Ltd	60
Nanjing Search Biotech Co., Ltd	68

View Lastest Price from Fluorescamine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-15	Fluorescamine 38183-12-9	$33.00-63.00		97.01%	10g	TargetMol Chemicals Inc.
	2020-02-04	Fluorescamine 38183-12-9	$1.00	1KG	98-99.9%	100kg	Career Henan Chemical Co

Fluorescamine
38183-12-9
$33.00-63.00
97.01%
TargetMol Chemicals Inc.

Fluorescamine
38183-12-9
$1.00
98-99.9%
Career Henan Chemical Co

Fluorescamine Spectrum

Fluorescamine(38183-12-9)¹HNMR Fluorescamine(38183-12-9)¹³CNMR Fluorescamine(38183-12-9)IR1 Fluorescamine(38183-12-9)Raman

38183-12-9(Fluorescamine)Related Search:

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Fura 2-AM FLUORESCIN Fluorescein Glyceryl monostearate Stearic acid hydrazide

1,2-Benzenedimethanol 2,3-Dihydrofuran Fluorescent powder 4-Phenyl-2-butanol 3-Acetoxy-2-butanone

1-Phenyl-2-butanone Acetic acid 3-phenyl-but-3-enyl ester Poly(tetrahydrofuran) standard 15000

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FLUORESCAMINE FLUORESCAMINE SPRAY REAGENT FLURAM(R) 4'-PHENYL-SPIRO[2-BENZOFURAN-1(3H),2'(3'H)-FURAN]-2',3-DIONE 4-PHENYL SPIRO-[FURAN-2(3H),1-PHTHALAN]-3,3'-DIONE 4-PHENYLSPIRO[FURAN-2(3H),1'-PHTHALAN]-3,3'-DIONE SPIRO[FURAN-2(3H),1'(3'H)-ISOBENZOFURAN]-3,3'-DIONE, 4-PHENYL- RO 20-7234 4-phenylspiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dione Fluorescamine [for HPLC Labeling] FLURAM(R) (FLUORESCAMINE), FOR FLUORESCE NCE FluorescamineA.R. Fluorescamine, pure FLUORESCAMINE extrapure AR 4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3μ-dione, Fluorescamine Supelco(R) TLC Spray Reagents FLURAMANALYTICAL GRADE Fluram,4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3′-dione, Fluorescamine Fluorescamine,4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3′-dione Fluorescamine, reagent grade Fluorescamin Fluaram FluorescaMine, pure 100MG FluorescaMine, pure 25MG FluorescaMine, pure 500MG 4-phenyl-3H,3'H-spiro[furan-2,1'-isobenzofuran]-3,3'-dione 4'-phenylspiro[2-benzofuran-3,2'-furan]-1,3'-dione Fluorescamine, For TLC analysis Fluorescamine *CAS 38183-12-9* Fluorescamine Labeling Fluorescamine, 98%, for synthesis 4''-phenyl-3H,3''H-spiro[2-benzofuran-1,2''-furan]-3,3''-dione Fluorescamine extrapure AR, ExiPlus, Multi-Compendial, 99% 4'-phenyl-3,3'-dihydrospiro[2-benzofur an-1,2'-furan]-3,3'-dione Fluorescamine, 10 mM in DMSO Fluorescamine,38183-12-9 4-phenylspiro[furan-2(3H),1-dihydroisobenzofuran]-3,3'-dione FLURAM 38183-12-9 39183-12-9 C17H10O4 Peptide Analysis and Characterization Other Fluorescent Labels Fluorescent Probes, Labels, Particles and Stains Fluorescent Labels Functional Group Reactive Labels Functional Group Reactive Labels for Flow Cytometry Detection Biochemicals and Reagents Amino Acid Analysis Reagents Amino Acids and Peptides BioChemical Amino Acid Analysis Amino Group Labeling Reagents for Fluorescence HPLC HPLC Labeling Reagents Fluorescence Detection (HPLC Labeling Reagents) marker Amino Acid Analysis