ANTAZOLINE PHOSPHATE
- CAS No.
- 154-68-7
- Chemical Name:
- ANTAZOLINE PHOSPHATE
- Synonyms
- ANTAZOLINE H3PO4;2-(N-Benzylanili;ANTISTIN PHOSPHATE;HISTOSAB PHOSPHATE;Antistine phosphate;ANTAZOLINE PHOSPHATE;ANTAZOLINE PHOSPHATE SALT;Antazoline Phosphate (200 mg);Antazoline Phosphate (1038003);ANTAZOLINE PHOSPHATE CRYSTALLINE
- CBNumber:
- CB8771906
- Molecular Formula:
- C17H22N3O4P
- Molecular Weight:
- 363.35
- MDL Number:
- MFCD00054317
- MOL File:
- 154-68-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 194-198° |
|---|---|
| storage temp. | Refrigerator |
| solubility | DMSO, Methanol |
| color | White |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C17H19N3.H3O4P/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;1-5(2,3)4/h1-10H,11-14H2,(H,18,19);(H3,1,2,3,4) |
| InChIKey | DUIGUKRYYAGJAF-UHFFFAOYSA-N |
| SMILES | OP(O)(O)=O.C1CN=C(CN(Cc2ccccc2)c3ccccc3)N1 |
| CAS DataBase Reference | 154-68-7(CAS DataBase Reference) |
| FDA UNII | VPR5FPH326 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HS Code | 2933290000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
ANTAZOLINE PHOSPHATE price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3455 | Antazoline Phosphate certified reference material, pharmaceutical secondary standard | 154-68-7 | 500MG | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1038003 | Antazoline phosphate United States Pharmacopeia (USP) Reference Standard | 154-68-7 | 200mg | $435 | 2026-04-30 | Buy |
| Sigma-Aldrich | A3766 | Antazoline phosphate salt analytical standard, for drug analysis | 154-68-7 | 1g | $37.8 | 2022-05-15 | Buy |
| TRC | TRC-A678410-1G | Antazoline Phosphate | 154-68-7 | 1g | $129 | 2026-06-03 | Buy |
| TRC | TRC-A678410-10G | Antazoline Phosphate | 154-68-7 | 10g | $190 | 2026-06-03 | Buy |
ANTAZOLINE PHOSPHATE Chemical Properties,Uses,Production
Uses
Antazoline Phosphate acts as a histamine H1 receptor blocker, functioning as an antihistamine pharmaceutical.
General Description
Antazoline phosphate, 2-[(Nbenzylanilino)methyl]-2-imidazoline dihydrogen phosphate,is a bitter, white to off-white crystalline powder thatis soluble in water. It has a pKa of 10.0, and a 2% solutionhas a pH of about 4.5. Antazoline, like the ethylenediamines,contains an N-benzylanilino group linked to a basicnitrogen through a two-carbon chain.
Antazoline is less active than most of the other antihistaminicdrugs, but it is characterized by the lack of local irritation.The more soluble phosphate salt is applied topicallyto the eye in a 0.5% solution. The less soluble hydrochlorideis given orally. In addition to its use as an antihistamine, antazolinehas more than twice the local anesthetic potency ofprocaine and also exhibits anticholinergic actions.
Biological Activity
Imidazoline agonist; more potent than efaroxan in inducing insulin release from β cells; H1 histamine receptor antagonist.
in vivo
Antazoline phosphate (IP; 0.01 ml/g; 30min) as H1 receptor antagonists diminishes the anticonvulsant activity of carbamazepine and diphenylhydantoin[3].
| Animal Model: | Swiss mice[3] |
| Dosage: | 0.01 mL/g |
| Administration: | IP; 0.01 ml/g; 30min |
| Result: | Showed some proconvulsive activity. |
ANTAZOLINE PHOSPHATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4484 | 50 | |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Guangzhou Kafen Biotech Co.,Ltd | 18029243487 2355327168 | gy@yccreate.com | China | 4738 | 55 |
| Wuhai Shuou Technology Co., Ltd. | 17792809151;18872220797 | 2355916837@ycphar.com | China | 6120 | 55 |
| Taian Jiaye Biotechnology Co.Ltd | 15318151873;13127280945 | 285424065@qq.com | China | 9961 | 55 |
| Amatek Scientific Co. Ltd. | 0512-56316828 400-867-5858;400-867-5858 | info@amateksci.com | China | 28763 | 58 |
| Wuhan Netcom Electronic Commerce Limited | 18064670521 | 2355935187@ycphar.com | China | 4870 | 58 |
View Lastest Price from ANTAZOLINE PHOSPHATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | ANTAZOLINE PHOSPHATE
154-68-7
|
$10.00 | 100KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-24 | Antazoline phosphate
154-68-7
|
1KG | 99.0% | 1000KG | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2019-09-02 | ANTAZOLINE PHOSPHATE
154-68-7
|
$1.00 | 1KG | 98% | 200kg | Career Henan Chemical Co |
-
- ANTAZOLINE PHOSPHATE
154-68-7
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Antazoline phosphate
154-68-7
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- ANTAZOLINE PHOSPHATE
154-68-7
- $1.00
- 98%
- Career Henan Chemical Co
