Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>MCL-1/BCL-2-IN-1

MCL-1/BCL-2-IN-1

MCL-1/BCL-2-IN-1 Structure
MCL-1/BCL-2-IN-1 structure
CAS No.
2493256-46-3
Chemical Name:
MCL-1/BCL-2-IN-1
Synonyms
MCL-1/BCL-2-IN-1;Benzamide, N-[2-[6-[(4-bromophenyl)thio]-1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl]ethyl]-4-(1,1-dimethylethyl)-
CBNumber:
CB88039563
Molecular Formula:
C31H27BrN2O3S
Molecular Weight:
587.53
MDL Number:
MOL File:
2493256-46-3.mol
MSDS File:
SDS
Last updated:2025-04-18 09:52:56
Request For Quotation

MCL-1/BCL-2-IN-1 Properties

Melting point 244-246 °C
Boiling point 770.940±60.00 °C(Press: 760.00 Torr)(predicted)
Density 1.469±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
form Solid
pka 14.445±0.46(predicted)
color Light yellow to yellow

MCL-1/BCL-2-IN-1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0107430 MCL-1/BCL-2-IN-1 98.65% 2493256-46-3 5mg $433 2026-06-04 Buy
ChemScene CS-0107430 MCL-1/BCL-2-IN-1 98.65% 2493256-46-3 10mg $737 2026-06-04 Buy
ChemScene CS-0107430 MCL-1/BCL-2-IN-1 98.65% 2493256-46-3 25mg $1137 2026-06-04 Buy
ChemScene CS-0107430 MCL-1/BCL-2-IN-1 98.65% 2493256-46-3 50mg $1896 2026-06-04 Buy
ChemScene CS-0107430 MCL-1/BCL-2-IN-1 98.65% 2493256-46-3 100mg $2492 2026-06-04 Buy
Product number Packaging Price Buy
CS-0107430 5mg $433 Buy
CS-0107430 10mg $737 Buy
CS-0107430 25mg $1137 Buy
CS-0107430 50mg $1896 Buy
CS-0107430 100mg $2492 Buy

MCL-1/BCL-2-IN-1 Chemical Properties, Uses, Production

Uses

MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 4.45 and 3.18 μM, respectively[1].

IC 50

Mcl-1: 4.45 μM (IC50); Bcl-2: 3.18 μM (IC50)

References

[1] Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. DOI:10.1021/acs.jmedchem.9b00919

MCL-1/BCL-2-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

MCL-1/BCL-2-IN-1 Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29873 58
Supplier Advantage
BOC Sciences 65
Shanghai YuanYe Biotechnology Co., Ltd. 60
Guangzhou Younan Technology Co., Ltd 58
TargetMol Chemicals Inc. 58

2493256-46-3 (MCL-1/BCL-2-IN-1) Related Search:

3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid AZD 5991 (AZD5991) DT2216 Anti-cancer compound library A-1155463
2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, (2R,3R)-rel-

1of2

MCL-1/BCL-2-IN-1 Benzamide, N-[2-[6-[(4-bromophenyl)thio]-1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl]ethyl]-4-(1,1-dimethylethyl)- 2493256-46-3