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6-Bromo-2-methyl-1,3-benzothiazole

6-Bromo-2-methyl-1,3-benzothiazole Structure
6-Bromo-2-methyl-1,3-benzothiazole structure
CAS No.
5304-21-2
Chemical Name:
6-Bromo-2-methyl-1,3-benzothiazole
Synonyms
6-broMo-2-Methylbenzo[d]thiazole;3-BENZOTHIAZOLE;6-BROMO-2-METHYL-1;6-BROMO-2-METHYLBENZOTHIAZOLE;2-Methyl-6-bromobenzothiazole;Benzothiazole, 6-bromo-2-methyl-;6-Bromo-2-methyl-1,3-benzothiazole;2-Methyl-benzothiazole-6-carbaldehyde;6-Bromo-2-methyl-1,3-benzothiazole 98%
CBNumber:
CB8839262
Molecular Formula:
C8H6BrNS
Molecular Weight:
228.11
MDL Number:
MFCD00466580
MOL File:
5304-21-2.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:53
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6-Bromo-2-methyl-1,3-benzothiazole Properties

Melting point 82-84
Boiling point 299.1±13.0 °C(Predicted)
Density 1.644±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka 1.00±0.10(Predicted)
color Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  22-36
Safety Statements  26
WGK Germany  3
Hazard Note  Irritant
HS Code  2934208090

6-Bromo-2-methyl-1,3-benzothiazole price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR12044 6-Bromo-2-methyl-1,3-benzothiazole 98% 5304-21-2 1g $45 2026-06-04 Buy
Apolloscientific OR12044 6-Bromo-2-methyl-1,3-benzothiazole 98% 5304-21-2 5g $128 2026-06-04 Buy
Apolloscientific OR12044 6-Bromo-2-methyl-1,3-benzothiazole 98% 5304-21-2 25g $463 2026-06-04 Buy
Synthonix B24105 6-Bromo-2-methylbenzo[d]thiazole 97% 5304-21-2 250mg $18 2026-05-06 Buy
Synthonix B24105 6-Bromo-2-methylbenzo[d]thiazole 97% 5304-21-2 1g $24 2026-05-06 Buy
Product number Packaging Price Buy
OR12044 1g $45 Buy
OR12044 5g $128 Buy
OR12044 25g $463 Buy
B24105 250mg $18 Buy
B24105 1g $24 Buy

6-Bromo-2-methyl-1,3-benzothiazole Chemical Properties,Uses,Production

Chemical Properties

Pale yellow liquid

Synthesis

4-BROMO-2-IODOACETANILDE

562080-91-5

6-BROMO-2-METHYL-1,3-BENZOTHIAZOLE

5304-21-2

General procedure for the synthesis of 6-bromo-2-methyl-1,3-benzothiazole from N-(4-bromo-2-iodophenyl)acetamide: N-(4-bromo-2-iodophenyl)acetamide (678 mg, 2.00 mmol) was dissolved in N,N-dimethylformamide (4.00 mL), followed by the addition of sodium sulfide nonahydrate (721 mg, 6.00 mmol) and copper iodide (I) (38.0 mg, 0.200 mmol). The reaction mixture was stirred at 80 °C. After the reaction was completed, it was cooled to room temperature, concentrated hydrochloric acid (1.6 mL) was added, and stirring was continued at 80 °C for 12 hours. At the end of the reaction, saturated aqueous sodium bicarbonate solution (20 mL) was added to neutralize. Extraction was performed with ethyl acetate (50 mL x 2). The organic layers were combined, washed with saturated aqueous sodium chloride solution and dried over anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure and the residue was purified by silica gel column chromatography to afford 6-bromo-2-methyl-1,3-benzothiazole (134 mg, 29.5% yield) using hexane/ethyl acetate (4:1, v/v) as eluent.

References

[1] Angewandte Chemie, International Edition, 2009, vol. 48, # 23, p. 4222 - 4225
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 18, p. 7241 - 7257
[3] Patent: JP2016/79108, 2016, A. Location in patent: Paragraph 0055
[4] Patent: JP2015/89879, 2015, A. Location in patent: Paragraph 0016; 0037; 0038; 0040

6-Bromo-2-methyl-1,3-benzothiazole synthesis

562080-91-5
5304-21-2
Synthesis of 6-Bromo-2-methyl-1,3-benzothiazole from 4-Bromo-2-iodoacetanilde

6-Bromo-2-methyl-1,3-benzothiazole Preparation Products And Raw materials

Raw materials

Benzothiazole, 4,6-dibromo-2-methyl- N-(2,4,6-tribromophenyl)acetamide 2-Amino-6-bromobenzothiazole 4-Bromo-2-iodoacetanilde 4-Bromo-2-(methylthio)aniline
6-Bromo-2-chlorobenzothiazole 4-Bromo-2-iodoaniline 4-Bromo-2-chloroacetanilide 2-Aminobenzenethiol Methylmagnesium Bromide
Acetaldehyde Thioacetamide

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Preparation Products

5-Bromo-2-methylbenzothiazole

6-Bromo-2-methyl-1,3-benzothiazole Suppliers

Global( 125)Suppliers
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Syntechem Co.,Ltd info@syntechem.com China 12973 57
ZhengZhou HuaWen Chemical Co.Ltd 0370-2785118 17550508557 675141927@qq.com China 3201 55
chenyue Chemicals Co., Ltd. +86-0519-85500896 benzoxazolone@163.com China 178 58
Beijing Taiya Jie Technology Development Co., Ltd. 021-33690831-8001 13552411790;18616022633 postmaster@tyjchem.cn China 1541 55
Wuhan Fortuna Chemical Co., Ltd 027-59207852 13308628970 buy@fortunachem.com China 2698 58
Supplier Advantage
Energy Chemical 61
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Pure Chemistry Scientific Inc. 62
Shanghai Longsheng chemical Co.,Ltd. 59
China DongFan Chemical Co.,LTD 66
Syntechem Co.,Ltd 57
ZhengZhou HuaWen Chemical Co.Ltd 55
chenyue Chemicals Co., Ltd. 58
Beijing Taiya Jie Technology Development Co., Ltd. 55
Wuhan Fortuna Chemical Co., Ltd 58

View Lastest Price from 6-Bromo-2-methyl-1,3-benzothiazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Bromo-2-methylbenzo[d]thiazole pictures 2026-08-25 6-Bromo-2-methylbenzo[d]thiazole
5304-21-2
 $10.00-50.00 1KG 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
6-bromo-2-methyl-Benzothiazole pictures 2022-09-01 6-bromo-2-methyl-Benzothiazole
5304-21-2
 10g 97% 98% 10kg Zhengzhou Gecko Scientific Inc.
6-Bromo-2-Methyl-1,3-Benzothiazole pictures 2022-01-15 6-Bromo-2-Methyl-1,3-Benzothiazole
5304-21-2
 1KG 99.1% 100 tons Honest Joy Holdings Limited

6-Bromo-2-methyl-1,3-benzothiazole Spectrum

6-BROMO-2-METHYL-1,3-BENZOTHIAZOLE(5304-21-2)1HNMR

5304-21-2(6-Bromo-2-methyl-1,3-benzothiazole)Related Search:

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6-BROMO-1,3-BENZOTHIAZOLE

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6-Bromo-2-methyl-1,3-benzothiazole 98% 6-BROMO-2-METHYLBENZOTHIAZOLE Benzothiazole, 6-bromo-2-methyl- 2-Methyl-6-bromobenzothiazole 3-BENZOTHIAZOLE 6-BROMO-2-METHYL-1 2-Methyl-benzothiazole-6-carbaldehyde 6-broMo-2-Methylbenzo[d]thiazole 6-Bromo-2-methyl-1,3-benzothiazole 5304-21-2