6-Bromobenzothiazole
- CAS No.
- 53218-26-1
- Chemical Name:
- 6-Bromobenzothiazole
- Synonyms
- 6-Bromobenzthiazol;6-BROMO-BENZOTHIAZOLE;BENZOTHIAZOLE, 6-BROMO-;6-Bromobenzothiazole,97%;6-BROMO-BENZO[D]THIAZOLE;6-BROMO-1,3-BENZOTHIAZOLE;Benzothiazole, 6-bromo- (9CI);6-Bromo-1,3-benzothiazole 97%;6-Bromo-1,3-benzothiazole ,97%
- CBNumber:
- CB9280191
- Molecular Formula:
- C7H4BrNS
- Molecular Weight:
- 214.08
- MDL Number:
- MFCD04115372
- MOL File:
- 53218-26-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 52-54℃ |
|---|---|
| Boiling point | 143 °C(Press: 12 Torr) |
| Density | 1.748±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Solid |
| pka | 0.21±0.10(Predicted) |
| color | Off-white to yellow |
| CAS DataBase Reference | 53218-26-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310a-P321-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| RIDADR | 2811 | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
6-Bromobenzothiazole price More Price(66)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B6336 | 6-Bromo-1,3-benzothiazole min. 98.0 % | 53218-26-1 | 5G | $170 | 2026-04-30 | Buy |
| ChemScene | CS-W003182 | 6-Bromobenzo[d]thiazole ≥98% | 53218-26-1 | 1g | $9 | 2026-06-04 | Buy |
| ChemScene | CS-W003182 | 6-Bromobenzo[d]thiazole ≥98% | 53218-26-1 | 5g | $26 | 2026-06-04 | Buy |
| ChemScene | CS-W003182 | 6-Bromobenzo[d]thiazole ≥98% | 53218-26-1 | 10g | $52 | 2026-06-04 | Buy |
| ChemScene | CS-W003182 | 6-Bromobenzo[d]thiazole ≥98% | 53218-26-1 | 25g | $127 | 2026-06-04 | Buy |
6-Bromobenzothiazole Chemical Properties, Uses, Production
Chemical Properties
Off-white powder
Uses
6-Bromobenzothiazole is a benzothiazole analogue. It can be used as a pharmaceutical intermediate or a raw material for the preparation of other aza-aromatic compounds.
Synthesis
533-30-2
53218-26-1
The general procedure for the synthesis of 6-bromobenzothiazole from 6-aminobenzothiazole was as follows: aqueous (1.0 mL) solution of sodium nitrite (0.147 g, 2.1 mmol) was slowly added dropwise to a mixture of 6-aminobenzothiazole (0.30 g, 2.0 mmol) suspended in a 48% aqueous hydrobromic acid solution (3 mL) at 0 °C. After the dropwise addition was completed, the reaction mixture was stirred at room temperature for 30 minutes. Subsequently, the resulting solution was slowly added to a hydrochloric acid solution (concentration not specified, 5 mL) of copper (I) bromide (0.435 g, 3.0 mmol) at 0 °C. After addition, the reaction system was warmed to 60 °C and stirred for 1.5 hours. Upon completion of the reaction, the reaction mixture was cooled, alkalized with excess ammonia and extracted with ether. The organic phases were combined, washed sequentially with water and saturated saline, dried anhydrous and concentrated. Purification by Combiflash fast chromatography afforded 6-bromobenzothiazole (0.26 g). This product was subsequently converted to the target compound using a similar procedure as in Example 1 , with mass spectrometry (ESI) detection showing (M + H)+ = 413.1.
References
[1] Organic Letters, 2007, vol. 9, # 18, p. 3623 - 3625
[2] Patent: WO2004/50659, 2004, A1. Location in patent: Page 49-50
[3] Patent: WO2014/151147, 2014, A1. Location in patent: Paragraph 00154
[4] Patent: US2014/357651, 2014, A1. Location in patent: Paragraph 0498
[5] Patent: US9174994, 2015, B2. Location in patent: Page/Page column 126
6-Bromobenzothiazole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. | 21-54820552 17702105771 | 188738128@qq.com | China | 300 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 |
View Latest Price from 6-Bromobenzothiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 6-Bromobenzothiazole
53218-26-1
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2019-07-06 | 6-BROMO-1,3-BENZOTHIAZOLE
53218-26-1
|
$8.00 | 1KG | 99% | 10tons | Career Henan Chemical Co |
-
- 6-Bromobenzothiazole
53218-26-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 6-BROMO-1,3-BENZOTHIAZOLE
53218-26-1
- $8.00
- 99%
- Career Henan Chemical Co
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