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7-Methoxy-4(1H)-quinazolinone

CAS No.
16064-24-7
Chemical Name:
7-Methoxy-4(1H)-quinazolinone
Synonyms
7-Methoxyquinazolin-4(3H)-one;7-Methoxy-4-quinazolinol;7-Methoxy-4(1H)-quinazolinone;7-Methoxy-3H-quinazolin-4-one;7-Methoxy-4(3h)-quinazolinone;7-Methoxyquinazolin-4(1H)-one;4(3H)-Quinazolinone, 7-methoxy-;7-methoxyquinolineazoleline-4(1H)-one;7-methoxy-1,4-dihydroquinazolin-4-one
CBNumber:
CB8848475
Molecular Formula:
C9H8N2O2
Molecular Weight:
176.17
MDL Number:
MFCD08460971
MOL File:
16064-24-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:53

7-Methoxy-4(1H)-quinazolinone Properties

Melting point 257-258℃
Boiling point 338.7±44.0 °C(Predicted)
Density 1.32
storage temp. 2-8°C
pka 1.51±0.20(Predicted)
Appearance Brown to black Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
HS Code  2933998090

7-Methoxy-4(1H)-quinazolinone price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 284923 7-Methoxy-4(3H)-quinazolinzone Asreported 16064-24-7 50mg $333 2026-06-03 Buy
Usbiological 284923 7-Methoxy-4(3H)-quinazolinzone Asreported 16064-24-7 100mg $482 2026-06-03 Buy
Usbiological 284923 7-Methoxy-4(3H)-quinazolinzone Asreported 16064-24-7 250mg $638 2026-06-03 Buy
Usbiological 284923 7-Methoxy-4(3H)-quinazolinzone Asreported 16064-24-7 1g $814 2026-06-03 Buy
Usbiological 284923 7-Methoxy-4(3H)-quinazolinzone Asreported 16064-24-7 2g $1062 2026-06-03 Buy
Product number Packaging Price Buy
284923 50mg $333 Buy
284923 100mg $482 Buy
284923 250mg $638 Buy
284923 1g $814 Buy
284923 2g $1062 Buy

7-Methoxy-4(1H)-quinazolinone Chemical Properties, Uses, Production

Synthesis

Formamidine acetate

3473-63-0

2-AMINO-4-METHOXY-BENZOIC ACID

4294-95-5

7-METHOXY-4(1H)-QUINAZOLINONE

16064-24-7

The general procedure for the synthesis of 7-methoxyquinazolin-4(1H)-one from formamidine acetate and 2-amino-4-methoxybenzoic acid was as follows: 1. 2-Amino-4-methoxybenzoic acid (4.85 g, 28.9 mmol) and formamidine acetate (18.49 g, 177.8 mmol) were mixed in 100 mL of 2-methoxyethanol. 2. The reaction mixture was heated to reflux and stirred under these conditions for 12 hours. 3. After completion of the reaction, the mixture was cooled to 25 °C. The reaction was carried out with 0.01 M 4. Dilute the cooled reaction mixture with 0.01 M aqueous ammonia solution (100 mL). 5. Continue stirring at 25 °C for 30 min. 6. Collect the light brown solid product formed by filtration. 7. Wash the solid product with 0.01 M aqueous ammonia solution. 8. 8. The final product 7-methoxyquinazolin-4(1H)-one was obtained by high vacuum drying in a yield of 11.5 g (73% yield). Product characterization data: NMR (δ, ppm): 12.10 (s, br, 1H), 8.05 (m, 2H), 7.10 (m, 2H), 3.90 (s, 3H); m/z 167.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 17, p. 4963 - 4966
[2] Patent: WO2007/71963, 2007, A2. Location in patent: Page/Page column 52
[3] Patent: CN104447769, 2016, B. Location in patent: Paragraph 0056-0057

7-Methoxy-4(1H)-quinazolinone Preparation Products And Raw materials

Global Suppliers ( 63)
Supplier Tel Email Country ProdList Advantage
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Nanjing Vital Chemical Co., Ltd. Please Send Email 18652950785 chemweiao@163.com China 4368 65
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Shanghai Carlow Chemicals Co., Ltd. 21-33526724 18930996265 info@carlowchem.com China 1820 50
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
BioPharmaMatrix,Inc. 0510-86010668 13395169561; sales@biopharmamatrix.com China 5018 55
Grader reagent 18221735425 sales@xinpingchem.com China 9925 58
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58

View Latest Price from 7-Methoxy-4(1H)-quinazolinone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
7-METHOXY-4(1H)-QUINAZOLINONE pictures 2020-01-13 7-METHOXY-4(1H)-QUINAZOLINONE
16064-24-7
$5.00 1KG 98% 100KG Career Henan Chemical Co

7-Methoxy-4(1H)-quinazolinone Spectrum

4(3H)-Quinazolinone, 7-methoxy- 7-Methoxyquinazolin-4(1H)-one 7-Methoxy-4(3h)-quinazolinone 7-methoxy-1,4-dihydroquinazolin-4-one 7-Methoxy-3H-quinazolin-4-one 7-Methoxy-4-quinazolinol 7-methoxyquinolineazoleline-4(1H)-one 7-Methoxyquinazolin-4(3H)-one 7-Methoxy-4(1H)-quinazolinone 16064-24-7