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FALECALCITRIOL

FALECALCITRIOL Structure
FALECALCITRIOL structure
CAS No.
83805-11-2
Chemical Name:
FALECALCITRIOL
Synonyms
Hornel;ST 630;Fulstan;Ro 23-4194;Fluorotriol;Flocalcitrol;Flocacitriol;Falecalcitol;Flocalcitriol;Falecalcitrio
CBNumber:
CB8849801
Molecular Formula:
C27H38F6O3
Molecular Weight:
524.58
MDL Number:
MFCD00870595
MOL File:
83805-11-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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FALECALCITRIOL Properties

Boiling point 576.9±50.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Store at -20°C,unstable in solution, ready to use.
solubility Soluble in DMSO
form Powder
pka 9.77±0.29(Predicted)
color White to off-white
InChIKey XPYGGHVSFMUHLH-QQAZGRHYNA-N
SMILES [C@@H]1(O)C/C(=C\C=C2/CCCC3(C)C/2CC[C@@H]3C(C)CCCC(O)(C(F)(F)F)C(F)(F)F)/C(=C)C(O)C1 |&1:0,15,r|
FDA UNII G70A8514T8

FALECALCITRIOL price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0801 Falecalcitriol 99.90% 83805-11-2 1mg $347 2026-06-04 Buy
ChemScene CS-0801 Falecalcitriol 99.90% 83805-11-2 5mg $1029 2026-06-04 Buy
ChemScene CS-0801 Falecalcitriol 99.90% 83805-11-2 10mg $1625 2026-06-04 Buy
ChemScene CS-0801 Falecalcitriol 99.90% 83805-11-2 25mg $3250 2026-06-04 Buy
ChemScene CS-0801 Falecalcitriol 99.90% 83805-11-2 50mg $5200 2026-06-04 Buy
Product number Packaging Price Buy
CS-0801 1mg $347 Buy
CS-0801 5mg $1029 Buy
CS-0801 10mg $1625 Buy
CS-0801 25mg $3250 Buy
CS-0801 50mg $5200 Buy

FALECALCITRIOL Chemical Properties, Uses, Production

Description

Falecalcitriol, previously known as flocalcitrol, was launched by several codevelopers in Japan for the treatment of secondary hyperthyroidism (SHPT). This hexafluorinated analog of 1α,25-dihydroxyvitamin D3 (calcitriol), the hormonally active form of vitamin D3, can be obtained by several different synthetic routes from a conveniently protected cholestenol, a key step being an aldol reaction with hexafluoroacetone. Falecalcitriol is several times more active than 1,25(OH)2D3 in regulating the proliferation of parathyroid cells and parathyroid hormone (PTH) synthesis that are believed to be mediated through binding to VDR, a nuclear receptor for vitamin D; furthermore, it was proposed that a bioactive 23S-hydroxylated metabolite, resistant to further metabolism, contributes to the retention of an active compound for longer in cells and so, to significantly lengthen the duration of action. In a comparative clinical study conducted in hemodialysis patients with moderate to severe SHPT, falecalcitriol was found to be more active than alfacalcidol in suppressing parathyroid hormone without triggering hypercalcemia.

Originator

University of Wisconsin (US)

Uses

Hexafluorinated analog of Calcitriol (C144500). A more potent therapeutic agent for secondary hyperparathyroidism.

brand name

Hornel, Fulstan

Hazard

A poison by ingestion.

FALECALCITRIOL Preparation Products And Raw materials

Raw materials

Preparation Products

FALECALCITRIOL Suppliers

Global Suppliers ( 105)
Supplier Tel Email Country ProdList Advantage
Wuhan Wsem Biological Co., Ltd. 027-83778876; 13667159345 13667159345@163.com China 1907 55
Chemvon Biotechnology Co., Ltd 021-50790412 info@chemvon.com China 371 57
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7545 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Hydragon Pharma Ltd 021-50215258 market@hypharma.com China 320 58
Gansu HaoTian Chemical Technology Co., Ltd. 0943-6900332 17789447501 zhuanxiajiang@haotianpharm.com China 182 55
Supplier Advantage
Wuhan Wsem Biological Co., Ltd. 55
Chemvon Biotechnology Co., Ltd 57
Chembest Research Laboratories Limited 61
Pure Chemistry Scientific Inc. 62
Chemsky (shanghai) International Co.,Ltd 60
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58
Quality Control Solutions Ltd. 56
Hydragon Pharma Ltd 58
Gansu HaoTian Chemical Technology Co., Ltd. 55

View Latest Price from FALECALCITRIOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Falecalcitriol pictures 2026-07-15 Falecalcitriol
83805-11-2
 $3980.00-5500.00 10g TargetMol Chemicals Inc.
FALECALCITRIOL pictures 2020-02-19 FALECALCITRIOL
83805-11-2
 $7.00 1KG 99% 100kg Career Henan Chemical Co

83805-11-2 (FALECALCITRIOL) Related Search:

5-(4-{2-[5-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-cyclohexylidene]-ethylidene}-7a-methyl-octahydro-inden-1-yl)-hexanoic acid ethyl ester methylene calcitriol INECALCITOL (S)-(-)-1,1,1-Trifluoroheptan-2-ol Calcifediol Monohydrate
Calcitriol FALECALCITRIOL VitaMin D4 CALCIFEDIOL (S)-(-)-1,1,1-Trifluorooctan-2-ol
(S)-(-)-1,1,1-Trifluoroundecan-2-ol (S)-(-)-1,1,1-Trifluorodecan-2-ol 1,1,1-Trifluoro-2-octanol (S)-(-)-1,1,1-Trifluorononan-2-ol (S)-(-)-1,1,1-Trifluorododecan-2-ol
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1of4

(+)-(5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1α,3β,25-triol 26,26,26,27,27,27-Hexafluoro-1,25-dihydroxyvitamin D3 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, 26,26,26,27,27,27-hexafluoro-, (1α,3β,5Z,7E)- Flocalcitriol Flocalcitrol Fulstan Hornel Ro 23-4194 ST 630 26,27-F6-1,25-(OH)2D3 F6-1,25(OH)2D3 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol 26,27-Hexafluoro-1α,25-dihydroxyvitamine D3 FALECALCITRIOL (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-Methyl-1-[(2R)-7,7,7-trifluoro-6-hydroxy-6-(trifluoromethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol (1R,4S,5Z)-4-Methylene-5-[(2E)-2-[1-[(1R)-6,6,6-trifluoro-5-hydroxy-1-Methyl-5-(trifluoroMethyl)hexyl]octahydro-7a-Methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol (1α,3β,5Z,7E)-26,26,26,27,27,27-Hexafluoro-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol F6-1α,25-DihydroxyvitaMin D3 Flocacitriol 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[1-[(1R)-6,6,6-trifluoro-5-hydroxy-1-methyl-5-(trifluoromethyl)hexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,4S,5Z)- Falecalcitol (1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-7a-Methyl-1-((R)-7,7,7-trifluoro-6-hydroxy-6-(trifluoromethyl)heptan-2-yl)octahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol Fluorocalcitriol Fluorotriol Falecalcitrio DSPE-PEG-Maleimide ammonium (MW 2000) 83805-11-2 C27H38F6O3 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals