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N,N-Dimethyl-L-proline

CAS No.
471-87-4
Chemical Name:
N,N-Dimethyl-L-proline
Synonyms
(-)-Stachydrine;N-Dimethyl-L-proline;1,1-dimethylpyrrolidinium-2-carboxylate;Cadabine;L-stachydrine;L-Proline betaine;Stachydrine, >98%;methyl hygrate bine;n,n-dimethyl-l-proline;Methyl hygrate betaine
CBNumber:
CB8854955
Molecular Formula:
C7H14NO2
Molecular Weight:
144.19
MDL Number:
MFCD09837899
MOL File:
471-87-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:36:19

N,N-Dimethyl-L-proline Properties

Melting point 235°C
Boiling point 261.28°C (rough estimate)
Density 1.1095 (rough estimate)
refractive index 1.4150 (estimate)
storage temp. 2-8°C
solubility Water: 100 mg/mL (698.42 mM); DMSO: 100 mg/mL (698.42 mM)
form Solid
color White to off-white
FDA UNII S1L688345C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  29214980

N,N-Dimethyl-L-proline price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 301008 Stachydrine ≥98% 471-87-4 20mg $349 2026-06-03 Buy
Biosynth FS65548 Stachydrine 471-87-4 500mg $170 2026-06-04 Buy
Biosynth FS65548 Stachydrine 471-87-4 1000mg $260 2026-06-04 Buy
Biosynth FS65548 Stachydrine 471-87-4 2000mg $360 2026-06-04 Buy
Biosynth FS65548 Stachydrine 471-87-4 5000mg $550 2026-06-04 Buy
Product number Packaging Price Buy
301008 20mg $349 Buy
FS65548 500mg $170 Buy
FS65548 1000mg $260 Buy
FS65548 2000mg $360 Buy
FS65548 5000mg $550 Buy

N,N-Dimethyl-L-proline Chemical Properties, Uses, Production

Description

This alkaloid, which has been isolated from the leaves of Cadaba fruticosa, has been shown, by comparison of its hydrochloride and the NMR spectrum, to be stachydrine.

Uses

Stachydrine is used for various ethnobotany and ethnomedicinal uses. It can also be used to promote healthy neural development in an unborn baby, as well as to determine the differential effects of post-weaning diet and maternal obesity on mouse liver and brain metabolomes.

Definition

ChEBI: L-proline betaine is an amino acid betaine that is L-proline zwitterion in which both of the hydrogens attached to the nitrogen are replaced by methyl groups. It has a role as a food component, a plant metabolite and a human blood serum metabolite. It is a N-methyl-L-alpha-amino acid, an alkaloid and an amino-acid betaine. It is functionally related to a L-prolinium. It is a conjugate base of a N,N-dimethyl-L-prolinium. It is an enantiomer of a D-proline betaine.

References

Ahmad, Basha, Atta-ur-Rahman, Pak. J. Sci. Ind. Res., 17, 109 (1975)

147-85-3
471-87-4
Synthesis of N,N-Dimethyl-L-proline from L-Proline

N,N-Dimethyl-L-proline Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 167)
Supplier Tel Email Country ProdList Advantage
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
Chengdu Climax Biotech Co., Ltd. 028-83311324 1278112614 climaxbiotech@gmail.com China 925 58
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Ruji Biology Technology Co., Ltd. +86-21-65211385-8001 36031160 sales@shruji.com China 3223 55
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Vientiane Tianjin Hengyuan Technology Co., Ltd. 15722085254 phytochemical@126.com China 813 55
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13323 58
Shanghai Yongye Biotechnology Co., Ltd. 86-021-61559134 15921386130 3423497944@qq.com China 8135 55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50

View Latest Price from N,N-Dimethyl-L-proline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N,N-Dimethyl-L-proline pictures 2026-08-07 N,N-Dimethyl-L-proline
471-87-4
$1.00-22.00 1KG 99% 100000KG Shaanxi Dideu Medichem Co. Ltd
Stachydrine pictures 2026-05-18 Stachydrine
471-87-4
$31.00-75.00 99.94% 10g TargetMol Chemicals Inc.
N,N-Dimethyl-L-proline pictures 2025-07-29 N,N-Dimethyl-L-proline
471-87-4
$6.00 1kg 99% 2000KG/Month HebeiShuoshengImportandExportco.,Ltd
  • Stachydrine pictures
  • Stachydrine
    471-87-4
  • $31.00-75.00
  • 99.94%
  • TargetMol Chemicals Inc.

N,N-Dimethyl-L-proline Spectrum

(2s)-1,1-dimethylpyrrolidinium-2-carboxylate (Pyrrolidinium, 2-carboxy-1,1-dimethyl-, innersalt, (2S)- Methyl hygrate betaine (S)-2-Carboxy-1,1-dimethylpyrrolidinium hydroxide inner salt 1-Methylproline methylbetaine Cadabine (2S)-1,1-Dimethyl-2-carboxylatopyrrolidin-1-ium (2S)-2-Carboxylato-1,1-dimethylpyrrolidin-1-ium (2S)-1,1-dimethylpyrrolidin-1-ium-2-carboxylate n,n-dimethyl-l-proline (s)-2-carboxylato-1,1-dimethylpyrrolidinium L-Proline betaine (S)-1,1-Dimethylpyrrolidin-1-ium-2-carboxylate Stachydrine, >98% L-stachydrine N,N-Dimethyl-L-Proline ( (-)-Stachydrine) N,N-Dimethyl-L-proline USP/EP/BP methyl hygrate bine NF-κB,Inhibitor,Nuclear factor-κB,Stachydrine,Endogenous Metabolite,inhibit,Nuclear factor-kappaB Stachydrine, 10 mM in DMSO (-)-Stachydrine 1,1-dimethylpyrrolidinium-2-carboxylate N-Dimethyl-L-proline 471-87-4 Alkaloids Natural Plant Extract