nifurfoline
- CAS No.
- 3363-58-4
- Chemical Name:
- nifurfoline
- Synonyms
- nifurfoline;3-[(Morpholino)methyl]-1-[(5-nitrofurfurylidene)amino]hydantoin;2,4-Imidazolidinedione, 3-(4-morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-;3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
- CBNumber:
- CB8911340
- Molecular Formula:
- C13H15N5O6
- Molecular Weight:
- 337.29
- MDL Number:
- MFCD00864944
- MOL File:
- 3363-58-4.mol
| Melting point | 206°; also reported as mp 194-196° |
|---|---|
| Boiling point | 486.5±55.0 °C(Predicted) |
| Density | 1.63±0.1 g/cm3(Predicted) |
| pka | 5.39±0.10(Predicted) |
| FDA UNII | SWQ65RJY2Z |
nifurfoline Chemical Properties, Uses, Production
Originator
Furobactil,Carrion,France,1974
Definition
ChEBI: Nifurfoline is an imidazolidine-2,4-dione.
Manufacturing Process
20 g of nitrofurantoin are placed in 100 cc of dimethylformamide and the solution is heated to 75°C to 80°C. This temperature is maintained and 100 cc of 40% formaldehyde are added, followed by 10 g of freshly distilled morpholine. The heating is continued for one hour, the mixture cooled and filtered and the precipitate obtained is washed with 95% alcohol. 20 g of the desired product are obtained as yellow crystals which melt at 206°C.
Therapeutic Function
Antibacterial
nifurfoline Preparation Products And Raw materials
nifurfoline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-029-81148696 18161915376 | 1027@dideu.com | China | 9989 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 58 |
