Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)-

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)-

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- Structure
1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- structure
CAS No.
1282606-48-7
Chemical Name:
1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)-
Synonyms
FUN06487;SCD1 inhibitor-3;SCD1 inhibitor-3, 10 mM in DMSO;1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)-;5-{1-[(4-fluorophenyl)methyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl}-N-[(pyridin-3-yl)methyl]-1H-pyrazole-3-carboxamide
CBNumber:
CB89797550
Molecular Formula:
C19H16FN7O2
Molecular Weight:
393.37
MDL Number:
MOL File:
1282606-48-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-18 07:23:31
Request For Quotation

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- Properties

Density 1.47±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 125 mg/mL (317.77 mM)
pka 11.56±0.10(Predicted)
form Solid
color White to off-white

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0179405 SCD1 inhibitor-3 98.24% 1282606-48-7 5mg $271 2026-06-04 Buy
ChemScene CS-0179405 SCD1 inhibitor-3 98.24% 1282606-48-7 10mg $412 2026-06-04 Buy
ChemScene CS-0179405 SCD1 inhibitor-3 98.24% 1282606-48-7 25mg $812 2026-06-04 Buy
ChemScene CS-0179405 SCD1 inhibitor-3 98.24% 1282606-48-7 50mg $1300 2026-06-04 Buy
ChemScene CS-0179405 SCD1 inhibitor-3 98.24% 1282606-48-7 100mg $1950 2026-06-04 Buy
Product number Packaging Price Buy
CS-0179405 5mg $271 Buy
CS-0179405 10mg $412 Buy
CS-0179405 25mg $812 Buy
CS-0179405 50mg $1300 Buy
CS-0179405 100mg $1950 Buy

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- Chemical Properties, Uses, Production

Description

FUN06487, also known as SCD1 inhibitor-3, is a SCD1 inhibitor. This compound was first reported in WO 2011039358. This product has no formal name at the moment.

Uses

SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer[1].

in vivo

SCD1 inhibitor-3 (compound 17a) (5 mg/kg; p.o.; 4 hours) reduces the plasma C16:1/C16:0 triglycerides desaturation index by 54 %[1].
SCD1 inhibitor-3 (2~10 mg/kg; p.o.; 4 hours) makes a dose-responsive reduction of plasma triglycerides desaturation index[1].

Animal Model:Lewis rats[1]
Dosage:5 mg/kg
Administration:P.o.; 4 hours
Result:Reduced the plasma C16:1/C16:0 triglycerides desaturation index by 54 %.
Animal Model:Lewis rats[1]
Dosage:2~10 mg/kg
Administration:P.o.; 4 hours
Result:A dose-responsive reduction of plasma triglycerides desaturation index.

References

[1] Sun S, et al. Discovery of triazolone derivatives as novel, potent stearoyl-CoA desaturase-1 (SCD1) inhibitors. Bioorg Med Chem. 2015;23(3):455-465. DOI:10.1016/j.bmc.2014.12.014

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- Suppliers

Global Suppliers ( 25)
Supplier Tel Email Country ProdList Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4859 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Dezhou LonWel Pharmaceutical Technology Co., Ltd. 13761310616 39324283@qq.com China 1365 58
Fujian boshi pharmaceutical technology co. LTD 0595-22008920; 18120708884 393612455@qq.com China 257 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Changzhou Chenhong Biotechnology Co., Ltd. +86-0519-85788828 +86-13775037613 sales@chemrenpharm.com China 4058 58
InvivoChem 13549236410 sales@invivochem.cn China 6745 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Supplier Advantage
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Dezhou LonWel Pharmaceutical Technology Co., Ltd. 58
Fujian boshi pharmaceutical technology co. LTD 58
TargetMol Chemicals Inc. 58
Changzhou Chenhong Biotechnology Co., Ltd. 58
InvivoChem 58
TargetMol Chemicals Inc. 58

View Latest Price from 1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SCD1 inhibitor-3 pictures 2026-07-17 SCD1 inhibitor-3
1282606-48-7
 $84.00-313.00 99.50% 10g TargetMol Chemicals Inc.

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- Spectrum

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)-(1282606-48-7)1HNMR

1282606-48-7 (1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)-) Related Search:

CVT-12012 Anti-cancer compound library N-Cbz-L-Tryptophan D5D-IN-326 SCD1/5-IN-1
CAY10566

1of2

1H-Pyrazole-3-carboxamide, 5-[1-[(4-fluorophenyl)methyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]-N-(3-pyridinylmethyl)- SCD1 inhibitor-3 FUN06487 5-{1-[(4-fluorophenyl)methyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl}-N-[(pyridin-3-yl)methyl]-1H-pyrazole-3-carboxamide SCD1 inhibitor-3, 10 mM in DMSO 1282606-48-7