7-Bromo-1H-pyrrolo[2,3-c]pyridine
![7-Bromo-1H-pyrrolo[2,3-c]pyridine Structure](CAS/GIF/165669-35-2.gif)
- CAS No.
- 165669-35-2
- Chemical Name:
- 7-Bromo-1H-pyrrolo[2,3-c]pyridine
- Synonyms
- 7-BroMo-6-azaindole;7-Bromo-1H-pyrrolo[2,3-c]pyridine;1H-Pyrrolo[2,3-c]pyridine, 7-bromo-
- CBNumber:
- CB91119225
- Molecular Formula:
- C7H5BrN2
- Molecular Weight:
- 197.03
- MDL Number:
- MFCD03839909
- MOL File:
- 165669-35-2.mol
- MSDS File:
- SDS
| Melting point | 174-178°C |
|---|---|
| Boiling point | 362.0±22.0 °C(Predicted) |
| Density | 1.770±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | solid |
| pka | 12.99±0.40(Predicted) |
| Appearance | Yellow to brown Solid |
| InChI | 1S/C7H5BrN2/c8-7-6-5(1-3-9-6)2-4-10-7/h1-4,9H |
| InChIKey | HTQAZKOPQOXNHI-UHFFFAOYSA-N |
| SMILES | Brc1nccc2cc[nH]c12 |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H318-H335 |
| Precautionary statements | P261-P280-P301+P310-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | T |
| Risk Statements | 25-37/38-41 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HS Code | 2933399990 |
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
7-Bromo-1H-pyrrolo[2,3-c]pyridine price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 732168 | 7-Bromo-6-azaindole 95% | 165669-35-2 | 500mg | $132 | 2023-06-20 | Buy |
| AstaTech | 58342 | 7-BROMO-1H-PYRROLO[2,3-C]PYRIDINE 97% | 165669-35-2 | 0.25G | $39 | 2026-04-30 | Buy |
| AstaTech | 58342 | 7-BROMO-1H-PYRROLO[2,3-C]PYRIDINE 97% | 165669-35-2 | 1G | $87 | 2026-04-30 | Buy |
| AstaTech | 58342 | 7-BROMO-1H-PYRROLO[2,3-C]PYRIDINE 97% | 165669-35-2 | 5G | $277 | 2026-04-30 | Buy |
| Apolloscientific | OR345276 | 7-Bromo-1h-pyrrolo[2,3-c]pyridine 98% | 165669-35-2 | 100mg | $30 | 2026-06-04 | Buy |
7-Bromo-1H-pyrrolo[2,3-c]pyridine Chemical Properties, Uses, Production
Synthesis
19755-53-4
1826-67-1
![7-BROMO-1H-PYRROLO[2,3-C]PYRIDINE](/CAS/GIF/165669-35-2.gif)
165669-35-2
Example 1: Synthesis of [1-(4-methoxy-benzenesulfonyl)-1H-pyrrolo[2,3-c]pyridin-7-yl]-phenyl-amine (Compound 1); 7-bromo-6-azaindole (2 in Scheme 1): 2-bromo-3-nitropyridine (1 in Schemes 1,2, 2.0 g, 98%, 9.7 mmol) was dissolved in anhydrous THF (80 mL) and cooled the solution to -78 °C. An excess of vinyl magnesium bromide (1.0 M solution of THF, 40 mL, 40 mmol) was slowly added under nitrogen protection. The reaction mixture was stirred at -40 to -50 °C for 1 h. The reaction was subsequently quenched with saturated NaHCO3 solution. The organic and aqueous layers were separated and the aqueous layer was extracted with EtOAc (3 times). The organic layers were combined, dried with anhydrous MgSO4, filtered and the filtrate concentrated. The residue was purified by fast chromatography (eluent: EtOAc/hexane=1:2) to afford the target product 2 (1.1 g, 60%).1H NMR (500 MHz, CDCl3): δ 6.66 (dd, 1H, J=2.9,2.1Hz), 7.43 (dd, 1H, J=2.9,2.1Hz), 7.51 (d, 1H, J =5.2Hz), 8.03 (d, 1H, J=5.3Hz), 8.79 (br, 1H).
References
[1] Patent: WO2011/19634, 2011, A2. Location in patent: Page/Page column 13
7-Bromo-1H-pyrrolo[2,3-c]pyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3828 | 58 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 4000 | 55 |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3537 | 55 |
| Shanghai Devinchem Ltd | 027-65318838 13646286950 | sales@devinchem.com | China | 2983 | 58 |
