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N-Acetyl-L-cysteine ethyl ester

N-Acetyl-L-cysteine ethyl ester Structure
N-Acetyl-L-cysteine ethyl ester structure
CAS No.
59587-09-6
Chemical Name:
N-Acetyl-L-cysteine ethyl ester
Synonyms
NACET;ethyl acetyl-L-cysteinate;101242;Acetylcysteine Impurity H;Ethyl N-acetyl-L-cysteinate;N-Acetylcysteine ethylester;Fenoxaprop-ethyl Impurity 17;N-Acetyl-L-cysteine Ethyl Este;N-Acetyl-L-cysteine ethyl ester;L-Cysteine, N-acetyl-, ethyl ester
CBNumber:
CB91177502
Molecular Formula:
C7H13NO3S
Molecular Weight:
191.25
MDL Number:
MFCD09954466
MOL File:
59587-09-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-03 18:11:14
Product description Number Pack Size Price
N-acetyl-L-Cysteine ethyl ester ≥95% 30299 5mg $49
N-acetyl-L-Cysteine ethyl ester ≥95% 30299 10mg $93
N-acetyl-L-Cysteine ethyl ester ≥95% 30299 50mg $213
N-acetyl-L-Cysteine ethyl ester ≥95% 30299 100mg $400
N-acetyl-L-Cysteine ethyl ester 30299 5mg $44
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N-Acetyl-L-cysteine ethyl ester Properties

Melting point 44.1-44.5 °C
Boiling point 337.6±32.0 °C(Predicted)
Density 1.138±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
form A crystalline solid
pka 9.17±0.10(Predicted)
color White to off-white
InChI InChI=1S/C7H13NO3S/c1-3-11-7(10)6(4-12)8-5(2)9/h6,12H,3-4H2,1-2H3,(H,8,9)/t6-/m0/s1
InChIKey MSMRAGNKRYVTCX-LURJTMIESA-N
SMILES C(OCC)(=O)[C@H](CS)NC(C)=O
FDA UNII HT8ACS9ZPT

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H315-H319-H413-H372
Precautionary statements  P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
NFPA 704
0
2 0

N-Acetyl-L-cysteine ethyl ester price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester ≥95% 59587-09-6 5mg $49 2026-04-30 Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester ≥95% 59587-09-6 10mg $93 2026-04-30 Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester ≥95% 59587-09-6 50mg $213 2026-04-30 Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester ≥95% 59587-09-6 100mg $400 2026-04-30 Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester 59587-09-6 5mg $44 2024-03-01 Buy
Product number Packaging Price Buy
30299 5mg $49 Buy
30299 10mg $93 Buy
30299 50mg $213 Buy
30299 100mg $400 Buy
30299 5mg $44 Buy

N-Acetyl-L-cysteine ethyl ester Chemical Properties,Uses,Production

Description

N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; ). It has enhanced cell permeability in isolated perfused rat liver compared to NAC. N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; ) in rats.

Uses

N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].

References

[1] Daniela Giustarini, et al. N-Acetylcysteine ethyl ester (NACET): a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Dec 1;84(11):1522-33. DOI:10.1016/j.bcp.2012.09.010

N-Acetyl-L-cysteine ethyl ester synthesis

118143-52-5
59587-09-6
Synthesis of N-Acetyl-L-cysteine ethyl ester from L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester

N-Acetyl-L-cysteine ethyl ester Preparation Products And Raw materials

Raw materials

L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester Ethanol N-Acetyl-L-cysteine

Preparation Products

N-Acetyl-L-cysteine ethyl ester Suppliers

Global( 163)Suppliers
Supplier Tel Email Country ProdList Advantage
Dingwang Technology (Wuhan) Co., Ltd. 		+undefined-27-2786652399 +undefined13627115097 market02@senwayer.com China 887 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3587 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3997 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
HR Biotechnology Co.,Ltd 		+8618565342020 sales@chemhy.com China 112 58
Shaanxi Haibo Biotechnology Co., Ltd 		+undefined18602966907 qinhe02@xaltbio.com China 997 58
Shandong Juchuang Chemical Co., LTD 		+16837774622 admin@juchuangchem.com China 295 58
Shaanxi Xianhe Biotech Co., Ltd 		+86-17709210191; +8617709210191 Jerry@xhobio.com China 906 58
HANGZHOU HAILAN CHEMICAL CO.,LTD. 		+86-57156122185 +86-15967590394 sales@hailan-chem.com China 2994 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Supplier Advantage
Dingwang Technology (Wuhan) Co., Ltd. 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
HR Biotechnology Co.,Ltd 		58
Shaanxi Haibo Biotechnology Co., Ltd 		58
Shandong Juchuang Chemical Co., LTD 		58
Shaanxi Xianhe Biotech Co., Ltd 		58
HANGZHOU HAILAN CHEMICAL CO.,LTD. 		58
Capot Chemical Co.,Ltd. 		60

View Lastest Price from N-Acetyl-L-cysteine ethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Acetyl-L-cysteine ethyl ester pictures 2026-06-05 N-Acetyl-L-cysteine ethyl ester
59587-09-6
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
N-Acetyl-L-cysteine ethyl ester pictures 2026-06-05 N-Acetyl-L-cysteine ethyl ester
59587-09-6
 1kg 0.99 2000KGS HANGZHOU HAILAN CHEMICAL CO.,LTD.
NACET N-Acetyl-L-cysteine ethyl ester pictures 2026-06-04 NACET N-Acetyl-L-cysteine ethyl ester
59587-09-6
 1kg 98% 1000 Xi an Biohorlden Industry Trade Co Ltd

N-Acetyl-L-cysteine ethyl ester Spectrum

N-Acetyl-L-cysteine ethyl ester(59587-09-6)1HNMR

59587-09-6(N-Acetyl-L-cysteine ethyl ester)Related Search:

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ethyl (2R)-2-acetamido-3-sulfanylpropanoate Acetylcysteine Impurity H 101242 2-acetamido-3-mercaptopropanoic acid ethyl ester Ethyl N-acetyl-L-cysteinate N-Acetyl-L-cysteine ethyl ester L-Cysteine, N-acetyl-, ethyl ester N-Acetylcysteine ethylester (R)-ethyl 2-acetaMido-3-Mercaptopropanoate (R)-Methyl 2-acetaMido-3-Mercaptopropanoate -Ethyl 2-acetamido-3-mercaptopropanoate NACET Synonyms: N-Acetyl-L-cysteine ethyl ester N-ethyl cool-L-cysteine ethyl ester N-Acetyl-L-cysteine Ethyl Ester (NACET) Fenoxaprop-ethyl Impurity 17 N-Acetyl-L-cysteine Ethyl Este NACET N-Acetyl-L-cysteine ethyl ester N-Acetyl-L-cysteine ethyl ester - [A71501] ethyl acetyl-L-cysteinate NACET 59587-09-6 59587-09-6