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N-Acetyl-L-cysteine ethyl ester

N-Acetyl-L-cysteine ethyl ester Structure
N-Acetyl-L-cysteine ethyl ester structure
CAS No.
59587-09-6
Chemical Name:
N-Acetyl-L-cysteine ethyl ester
Synonyms
NACET;101242;Acetylcysteine Impurity H;ethyl acetyl-L-cysteinate;Ethyl N-acetyl-L-cysteinate;N-Acetylcysteine ethylester;Fenoxaprop-ethyl Impurity 17;N-Acetyl-L-cysteine Ethyl Este;N-Acetyl-L-cysteine ethyl ester;L-Cysteine, N-acetyl-, ethyl ester
CBNumber:
CB91177502
Molecular Formula:
C7H13NO3S
Molecular Weight:
191.25
MDL Number:
MFCD09954466
MOL File:
59587-09-6.mol
MSDS File:
SDS
Last updated:2025-09-17 10:44:43
Product description Number Pack Size Price
N-acetyl-L-Cysteine ethyl ester 30299 5mg $44
N-acetyl-L-Cysteine ethyl ester 30299 10mg $84
N-acetyl-L-Cysteine ethyl ester 30299 50mg $193
N-acetyl-L-Cysteine ethyl ester 30299 100mg $363
L-Cysteine,N-acetyl-,ethylester 0446CB 100mg $502
More product size
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N-Acetyl-L-cysteine ethyl ester Properties

Melting point 44.1-44.5 °C
Boiling point 337.6±32.0 °C(Predicted)
Density 1.138±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
form A crystalline solid
pka 9.17±0.10(Predicted)
color White to off-white
InChI InChI=1S/C7H13NO3S/c1-3-11-7(10)6(4-12)8-5(2)9/h6,12H,3-4H2,1-2H3,(H,8,9)/t6-/m0/s1
InChIKey MSMRAGNKRYVTCX-LURJTMIESA-N
SMILES C(OCC)(=O)[C@H](CS)NC(C)=O
FDA UNII HT8ACS9ZPT

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H315-H319-H413-H372
Precautionary statements  P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
NFPA 704
0
2 0

N-Acetyl-L-cysteine ethyl ester price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester 59587-09-6 5mg $44 2024-03-01 Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester 59587-09-6 10mg $84 2024-03-01 Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester 59587-09-6 50mg $193 2024-03-01 Buy
Cayman Chemical 30299 N-acetyl-L-Cysteine ethyl ester 59587-09-6 100mg $363 2024-03-01 Buy
AK Scientific 0446CB L-Cysteine,N-acetyl-,ethylester 59587-09-6 100mg $502 2021-12-16 Buy
Product number Packaging Price Buy
30299 5mg $44 Buy
30299 10mg $84 Buy
30299 50mg $193 Buy
30299 100mg $363 Buy
0446CB 100mg $502 Buy

N-Acetyl-L-cysteine ethyl ester Chemical Properties,Uses,Production

Description

N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; ). It has enhanced cell permeability in isolated perfused rat liver compared to NAC. N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; ) in rats.

Uses

N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].

References

[1] Daniela Giustarini, et al. N-Acetylcysteine ethyl ester (NACET): a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Dec 1;84(11):1522-33. DOI:10.1016/j.bcp.2012.09.010

N-Acetyl-L-cysteine ethyl ester synthesis

118143-52-5
59587-09-6
Synthesis of N-Acetyl-L-cysteine ethyl ester from L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester

N-Acetyl-L-cysteine ethyl ester Preparation Products And Raw materials

Raw materials

L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester Ethanol N-Acetyl-L-cysteine

Preparation Products

N-Acetyl-L-cysteine ethyl ester Suppliers

Global( 148)Suppliers
Supplier Tel Email Country ProdList Advantage
Wuhan senwayer century chemical Co.,Ltd 		+undefined-27-86652399 +undefined13627115097 market02@senwayer.com China 922 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3587 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 4000 58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		+8613288715578 sales@sichuanzyyt.com China 12247 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Wuhan Haorong Biotechnology Co.,ltd 		+8618565342920 sales@chembj.net China 300 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8615965530500 nickzhang@hangyubiotech.com China 10996 58
Shaanxi Haibo Biotechnology Co., Ltd 		+undefined18602966907 qinhe02@xaltbio.com China 997 58
Shandong Juchuang Chemical Co., LTD 		+16837774622 admin@juchuangchem.com China 295 58
Shaanxi Xianhe Biotech Co., Ltd 		+86-17709210191; +8617709210191 Jerry@xhobio.com China 883 58
Supplier Advantage
Wuhan senwayer century chemical Co.,Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Wuhan Haorong Biotechnology Co.,ltd 		58
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Shaanxi Haibo Biotechnology Co., Ltd 		58
Shandong Juchuang Chemical Co., LTD 		58
Shaanxi Xianhe Biotech Co., Ltd 		58

View Lastest Price from N-Acetyl-L-cysteine ethyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NACET N-Acetyl-L-cysteine ethyl ester pictures 2025-10-17 NACET N-Acetyl-L-cysteine ethyl ester
59587-09-6
 US $0.00-0.00 / kg 1kg 98% 1000 Xi an Biohorlden Industry Trade Co Ltd
N-Acetyl-L-cysteine ethyl ester pictures 2025-10-17 N-Acetyl-L-cysteine ethyl ester
59587-09-6
 US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
N-Acetyl-L-cysteine Ethyl Ester (NACET) pictures 2025-10-17 N-Acetyl-L-cysteine Ethyl Ester (NACET)
59587-09-6
 US $0.00 / kg 1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd

N-Acetyl-L-cysteine ethyl ester Spectrum

N-Acetyl-L-cysteine ethyl ester(59587-09-6)1HNMR

59587-09-6(N-Acetyl-L-cysteine ethyl ester)Related Search:

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ethyl (2R)-2-acetamido-3-sulfanylpropanoate Acetylcysteine Impurity H 101242 2-acetamido-3-mercaptopropanoic acid ethyl ester Ethyl N-acetyl-L-cysteinate N-Acetyl-L-cysteine ethyl ester L-Cysteine, N-acetyl-, ethyl ester N-Acetylcysteine ethylester (R)-ethyl 2-acetaMido-3-Mercaptopropanoate (R)-Methyl 2-acetaMido-3-Mercaptopropanoate -Ethyl 2-acetamido-3-mercaptopropanoate ethyl acetyl-L-cysteinate NACET NACET Synonyms: N-Acetyl-L-cysteine ethyl ester N-ethyl cool-L-cysteine ethyl ester N-Acetyl-L-cysteine Ethyl Ester (NACET) Fenoxaprop-ethyl Impurity 17 N-Acetyl-L-cysteine Ethyl Este NACET N-Acetyl-L-cysteine ethyl ester N-Acetyl-L-cysteine ethyl ester - [A71501] 59587-09-6 59587-09-6