2-Mercaptobenzooxazole-6-carboxylic acid methyl ester
- CAS No.
- 72752-81-9
- Chemical Name:
- 2-Mercaptobenzooxazole-6-carboxylic acid methyl ester
- Synonyms
- 6-bromo-5-fluoro-1,3-dihydroindol-6-one;5-ETHYL-7-METHOXY-BENZENESULFONYLCHLORIDE;Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate;methyl 2-mercapto-1,3-benzoxazole-6-carboxylate;Methyl 2-sulfanyl-1,3-benzoxazole-6-carboxylate;2-Mercaptobenzooxazole-6-carboxylic acid methyl ester;methyl 2-sulfanylidene-3H-1,3-benzoxazole-6-carboxylate;6-Benzoxazolecarboxylic acid, 2,3-dihydro-2-thioxo-, methyl ester
- CBNumber:
- CB91180379
- Molecular Formula:
- C9H7NO3S
- Molecular Weight:
- 209.22
- MDL Number:
- MFCD09261169
- MOL File:
- 72752-81-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate | 072939 | 250.00mg | $231 |
| Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate | 072939 | 1.00g | $500 |
| Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate | 072939 | 5.00g | $1340 |
| Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate 95% | A185951 | 250mg | $20 |
| Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate 95% | A185951 | 1g | $24 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
2-Mercaptobenzooxazole-6-carboxylic acid methyl ester price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 072939 | Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate | 72752-81-9 | 250.00mg | $231 | 2026-05-18 | Buy |
| Matrix Scientific | 072939 | Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate | 72752-81-9 | 1.00g | $500 | 2026-05-18 | Buy |
| Matrix Scientific | 072939 | Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate | 72752-81-9 | 5.00g | $1340 | 2026-05-18 | Buy |
| Ambeed | A185951 | Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate 95% | 72752-81-9 | 250mg | $20 | 2026-06-05 | Buy |
| Ambeed | A185951 | Methyl 2-mercaptobenzo[d]oxazole-6-carboxylate 95% | 72752-81-9 | 1g | $24 | 2026-06-05 | Buy |
2-Mercaptobenzooxazole-6-carboxylic acid methyl ester Chemical Properties,Uses,Production
Synthesis
140-89-6
63435-16-5
72752-81-9
The general procedure for the synthesis of methyl 2-mercaptobenzo[D]oxazole-6-carboxylate from potassium ethylxanthate and methyl 4-amino-3-hydroxybenzoate was as follows: a suspension of methyl 4-amino-3-hydroxybenzoate (393 g, 2.35 mol) and potassium ethylxanthate (393 g, 2.45 mol) in pyridine (3 L) was heated and refluxed for 12 hours. Completion of the reaction was confirmed by monitoring the progress of the reaction by thin layer chromatography (TLC, unfolding agent ratio ethyl acetate/petroleum ether = 1:2). The reaction mixture was cooled to room temperature and slowly poured into four 5L flasks containing 1600mL of concentrated hydrochloric acid and 10L of ice water, respectively. After vigorous stirring for 5 minutes, the solid product was collected by filtration. The solid was washed with 1 L of water and dried in air for 30 min. The dried solid was dissolved in 10 L of ethyl acetate and the organic phase was washed sequentially with 2 L of 1N hydrochloric acid and 1 L of saturated saline. The organic phase was dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target product methyl 2-mercaptobenzo[D]oxazole-6-carboxylate (390 g, 79.3% yield) as a pink solid.
References
[1] Patent: US2010/305073, 2010, A1. Location in patent: Page/Page column 21
[2] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 15, p. 4998 - 5002
[3] Patent: WO2018/85148, 2018, A1. Location in patent: Paragraph 0114
[4] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 7, p. 1975 - 1980
2-Mercaptobenzooxazole-6-carboxylic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9416 | 55 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10186 | 62 |
| Shanghai Paulshine Chemical Co., Ltd. | +86-021-37788663 | China | 186 | 64 |
