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Scopolamine butylbromide

Scopolamine butylbromide Structure
Scopolamine butylbromide structure
CAS No.
149-64-4
Chemical Name:
Scopolamine butylbromide
Synonyms
HYOSCINE BUTYLBROMIDE;buscopan;HYOSCINE N-BUTYL BROMIDE;sporamin;butylhyoscine;Hyoscine butyl bromide BP;SCOPOLAMINE N-BUTYL BROMIDE;N-BUTYLSCOPOLAMMONIUM BROMIDE;(1S,2R,4S,5S)-9-butyl-7-[(3-hydroxy-2-phenylpropanoyl)oxy]-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide;buscol
CBNumber:
CB9126868
Molecular Formula:
C21H30BrNO4
Molecular Weight:
440.37
MDL Number:
MFCD00078561
MOL File:
149-64-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:07:35
Product description Number Pack Size Price
(?)-Scopolamine N-butyl bromide ≥98% (TLC), powder S7882 1g $60.3
Hyoscine butylbromide for system suitability European Pharmacopoeia (EP) Reference Standard Y0001983 15 mg $166
(?)-Scopolamine N-butyl bromide ≥98% (TLC), powder S7882 5g $189
Hyoscine butylbromide European Pharmacopoeia (EP) Reference Standard H1450000 20 mg $254
Hyoscine butylbromide British Pharmacopoeia (BP) Reference Standard BP198 100MG $263
More product size
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Scopolamine butylbromide Properties

Melting point 142-1440C
alpha D20 -20.8° (c = 3 in water)
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form powder
color white
optical activity [α]25/D 20.8°, c = 3 in H2O(lit.)
Major Application pharmaceutical
pharmaceutical small molecule
InChIKey HOZOZZFCZRXYEK-YNXDNFBCNA-M
SMILES [C@]12([H])O[C@@]1([H])[C@@]1([H])[N+](C)(CCCC)[C@]2([H])C[C@@H](OC(=O)[C@H](CO)C2C=CC=CC=2)C1.[Br-] |&1:0,3,5,13,16,20,r|
CAS DataBase Reference 149-64-4(CAS DataBase Reference)
FDA UNII 0GH9JX37C8
NCI Drug Dictionary butylscopolamine bromide
UNSPSC Code 41116107
NACRES NA.24

Pharmacokinetic data

Protein binding 10%
Excreted unchanged in urine 1-2%
Biological half-life 8 / -

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H332
Precautionary statements  P261-P264-P270-P271-P301+P312-P304+P340+P312
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  YM3500000
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Toxicity LD50 in mice (mg/kg): 15.6 i.v.; 74 i.p.; 570 s.c.; 3000 orally (Stockhaus, Wick)
NFPA 704
0
3 0

Scopolamine butylbromide price More Price(69)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S7882 (?)-Scopolamine N-butyl bromide ≥98% (TLC), powder 149-64-4 1g $60.3 2026-04-30 Buy
Sigma-Aldrich Y0001983 Hyoscine butylbromide for system suitability European Pharmacopoeia (EP) Reference Standard 149-64-4 15 mg $166 2026-04-30 Buy
Sigma-Aldrich S7882 (?)-Scopolamine N-butyl bromide ≥98% (TLC), powder 149-64-4 5g $189 2026-04-30 Buy
Sigma-Aldrich H1450000 Hyoscine butylbromide European Pharmacopoeia (EP) Reference Standard 149-64-4 20 mg $254 2026-04-30 Buy
Sigma-Aldrich BP198 Hyoscine butylbromide British Pharmacopoeia (BP) Reference Standard 149-64-4 100MG $263 2026-04-30 Buy
Product number Packaging Price Buy
S7882 1g $60.3 Buy
Y0001983 15 mg $166 Buy
S7882 5g $189 Buy
H1450000 20 mg $254 Buy
BP198 100MG $263 Buy

Scopolamine butylbromide Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Originator

Butylscopolamine,China Pharm

Uses

Anticholinergic. Antispasmodic

Uses

()-Scopolamine N-butyl bromide was used as standard in designing a procedure for quantification of compounds using CE-MS.8

Definition

ChEBI: Butylscopolamine bromide is an organic bromide salt of butylscopolamine. It is an antispasmodic drug which can relieve painful stomach cramps (including those linked with irritable bowel syndrome), bladder and menstrual cramps. It has a role as a muscarinic antagonist and an antispasmodic drug. It is an organic bromide salt and a quaternary ammonium salt. It contains a butylscopolamine.

Manufacturing Process

1300 g of scopolamine base and 350 g of n-butylbromide in 600 ml acetonitrile is heated at 65°C for 160 hours. The oil obtained is dissolved in methanol. The solution is cooled and crystalline scopolamine N-n-butylbromide is filtered. After recrystallization from methanol was obtained scopolamine N-n-butylbromide with melting point 142-144°C and [α]d 20 = -20.5° (3% solution in water); yield 65%.

Therapeutic Function

Anticholinergic, Spasmolytic, Antitussive

Biochem/physiol Actions

Competitive muscarinic acetylcholine receptor antagonist; antispasmodic.

Clinical Use

Symptomatic relief of gastrointestinal or genitourinary disorders due to smooth muscle spasm Bowel colic
Excessive respiratory secretions

target

AChR

Metabolism

The main metabolic pathway is the hydrolytic cleavage of the ester bond. Orally administered hyoscine butylbromide is excreted in the faeces and in the urine. Studies in man show that 2-5% of radioactive doses is eliminated renally after oral, and 0.7-1.6% after rectal administration. Approximately 90% of recovered radioactivity can be found in the faeces after oral administration. The urinary excretion of hyoscine butylbromide is less than 0.1% of the dose. The metabolites excreted via the renal route bind poorly to muscarinic receptors and are therefore not considered to contribute to the effect of the hyoscine butylbromide.

Scopolamine butylbromide synthesis

74-83-9
14861-14-4
149-64-4
Synthesis of Scopolamine butylbromide from Methyl bromide and Benzeneacetic acid, α-(hydroxymethyl)-, 9-butyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, [7(S)-(1α,2β,4β,5α,7β)]- (9CI)

Scopolamine butylbromide Preparation Products And Raw materials

Raw materials

Scopolamine 1-Bromobutane Benzeneacetic acid, α-(hydroxymethyl)-, 9-butyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, [7(S)-(1α,2β,4β,5α,7β)]- (9CI)

Preparation Products

Scopolamine butylbromide Suppliers

Global( 462)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2472 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		+86-15350851019; +8615350851019 admin@86-ss.com China 999 58
Shaanxi Xianhe Biotech Co., Ltd 		+86-17709210191; +8617709210191 Jerry@xhobio.com China 906 58
Wuhan JiyunZen Tech Co., Ltd. 		+86-18062099985 Amyjiyunzen@yeah.net China 672 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 4616 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Supplier Advantage
Hebei Yanxi Chemical Co., Ltd. 		58
Henan Bao Enluo International TradeCo.，LTD 		58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		58
Shaanxi Xianhe Biotech Co., Ltd 		58
Wuhan JiyunZen Tech Co., Ltd. 		58
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Chengdu GLP biotechnology Co Ltd 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58

View Lastest Price from Scopolamine butylbromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Scopolamine butylbromide pictures 2026-06-05 Scopolamine butylbromide
149-64-4
 $800.00-999.00 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Scopolamine butylbromide pictures 2026-06-05 Scopolamine butylbromide
149-64-4
 0.99 RongNa Biotechnology Co.,Ltd
Scopolamine butylbromide; Flos?daturae extract pictures 2026-06-05 Scopolamine butylbromide; Flos?daturae extract
149-64-4
 1G ≥99% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.

Scopolamine butylbromide Spectrum

Scopolamine butylbromide(149-64-4)MS

149-64-4(Scopolamine butylbromide)Related Search:

Dimidium bromide Racanisodamine Allyl bromide Ethidium bromide Rocuronium bromide
Cyhalofop-butyl L-Hyoscyamine Buprofezin 1-Bromobutane Vecuronium bromide
Scopolamine hydrobromide Anisodamine Sodium bromate Scopolamine SCOPOLAMINE N-OXIDE HYDROBROMIDE
Scopolamine Hydrobromide Trihydrate (-)-SCOPOLAMINE SCOPOLAMINE-D3 HYDROBROMIDE Hyoscine Butylbromide

1of4

BUTYLMIN SCOPOLAMINI BUTYLBROMIDUM (-)-SCOPOLAMINE N-BUTYL BROMIDE (-)-N-BUTYLSCOPOLAMIDE BROMIDE 5-alpha-h-tropanium,8-butyl-6-beta,7-beta-epoxy-3-alpha-hydroxy-1-alpha-br amisepan buscapina buscapine buscol buscolamin buscolysin buscolysine butylscopolaminebromide butylscopolammoniumbromide donopon hyoscinebutobromide hyoscin-n-butylbromid hyoscin-n-butylbromide joscine monospan n-butylhyoscinebromide n-butylhyosciniumbromide n-butylscopolaminiumbromide omide,(-)-tropate scobro scobron scobutil scobutyl scopolaminebromobutylate scopolaminebutobromide scopolaminebutylbromide scopolan sparicon stilbron tirantil hyoscine butylobromide HYOSCINE BUTYLBROMIDE STANDARD ScopolaMine ButylborMide (Hyoscine ButylbroMide) 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-Methyl-, broMide (1:1), (1a,2b,4b,5a,7b)- Hyoscine butylbromide Impurity Ding bromate scopolamine Hyoscinen buty1bromide Ding bromine scopolamine ()-N-Butylscopolamine bromide ()-Scopolamine N-butyl bromide Hyoscine N-butyl bromide (1S,2R,4S,5S)-9-butyl-7-[(3-hydroxy-2-phenylpropanoyl)oxy]-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide (1S,2R,4S,5S)-9-butyl-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide (1S,2R,4S (-)-SCOPOLAMINE N-BUTYL BROMIDE CHOLINERGIC ANTAGONIST 3-Oxa-9-azoniatricyclo3.3.1.02,4nonane, 9-butyl-7-(2S)-3-hydroxy-1-oxo-2-phenylpropoxy-9-methyl-, bromide, (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)- 1aH,5aH-Tropanium, 8-butyl-6b,7b-epoxy-3a-hydroxy-, bromide, (-)-tropate (8CI) 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, [7(S)-(1a,2b,4b,5a,7b)]- 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1a,2b,4b,5a,7b)- (9CI) Sporamin (pharmaceutical) Stibron Tropic acid, (-)-, ester with 8-butyl-6b,7b-epoxy-3a-hydroxy-1a-H,5aH-tropanium bromide (8CI) (-)-Scopolamin-n-butylbromid (-)-SCOPOLAMINE N-BUTYL BROMIDE 99% ButylscopolaMine BR (ScopolaMine butylbroMide)