A 62198
- CAS No.
- 117978-26-4
- Chemical Name:
- A 62198
- Synonyms
- A 62198;Reaxys ID: 26144718;5-Azido-1-cyclohexyl-1,2,5-trideoxy-2-[[N-[N-(2-methyl-1-oxopropyl)-L-phenylalanyl]-L-histidyl]amino]-L-arabino-pentitol;N-[1-[[1-[(5-azido-1-cyclohexyl-3,4-dihydroxy-pentan-2-yl)carbamoyl]-2-(3H-imidazol-4-yl)ethyl]carbamoyl]-2-phenyl-ethyl]-2-methyl-propanamide
- CBNumber:
- CB91358596
- Molecular Formula:
- C30H44N8O5
- Molecular Weight:
- 596.72
- MDL Number:
- MFCD00877827
- MOL File:
- 117978-26-4.mol
- MSDS File:
- SDS
A 62198 Chemical Properties, Uses, Production
Description
A 62198 is a potent and selective renin inhibitor. A-62198 induced a dose-dependent fall in mean arterial blood pressure (MAP) when administered as an i.v. bolus to anesthetized, salt-depleted monkeys. It has potential as a hypotensive agent.
Uses
A-62198 is a potent and selective renin inhibitor with antihypertensive activity. A-62198 reduces mean arterial pressure (MAP) in anesthetized, salt-deprived monkeys in a dose-dependent manner. A-62198 induced MAP reduction in normal monkeys that reached statistical significance at the highest dose and significantly inhibited plasma renin activity (PRA) at all doses[1].
References
[1] Cardiovascular actions of the primate-selective renin inhibitor, A-62198 PMID:3047366
A 62198 Preparation Products And Raw materials
Raw materials
Preparation Products
A 62198 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
