NNC 687
- CAS No.
- 128022-68-4
- Chemical Name:
- NNC 687
- Synonyms
- ADX-10061;CEE-310;NNC 687;ADX10061;CEE-03-310;NNC-01-0687;ADX10061,ADX 10061
- CBNumber:
- CB91385145
- Molecular Formula:
- C19H20N2O4
- Molecular Weight:
- 340.37
- MDL Number:
- MOL File:
- 128022-68-4.mol
- MSDS File:
- SDS
| Boiling point | 477.305±45.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.311±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| pka | 6.775±0.40(predicted) |
| FDA UNII | K389NU4SEV |
NNC 687 Chemical Properties, Uses, Production
Uses
ADX-10061 (compound NNC 687) is a dopamine D1 receptor antagonist with the Ki values of 9.1 nM, 5.8 nM, > 10 000 nM and 355 nM for adenylyl cyclase, D1, D2 and 5-HT2 receptor, respectively. ADX-10061 can be used for study of schizophrenia[1].
IC 50
D1 Receptor: 5.8 nM (Ki); D2 Receptor: > >10 000 nM (Ki)
References
[1] Andersen PH, et al. NNC-112, NNC-687 and NNC-756, new selective and highly potent dopamine D1 receptor antagonists. Eur J Pharmacol. 1992;219(1):45-52. DOI:10.1016/0014-2999(92)90578-r
NNC 687 Preparation Products And Raw materials
Raw materials
Preparation Products
NNC 687 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |





