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Lipid HTO12

CAS No.
3047222-45-4
Chemical Name:
Lipid HTO12
Synonyms
Lipid HTO12
CBNumber:
CB915530407
Molecular Formula:
C41H83NO4
Molecular Weight:
654.1
MDL Number:
MOL File:
3047222-45-4.mol
MSDS File:
SDS
Last updated:2025-10-16 08:12:08

Lipid HTO12 Properties

Boiling point 703.061±45.00 °C(Press: 760.00 Torr)(predicted)
Density 0.919±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility Ethanol: Soluble: =10 mg/ml
pka 14.735±0.20(predicted)

Lipid HTO12 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 41202 Lipid HTO12 ≥98% 3047222-45-4 5mg $109 2026-04-30 Buy
Cayman Chemical 41202 Lipid HTO12 ≥98% 3047222-45-4 10mg $196 2026-04-30 Buy
Cayman Chemical 41202 Lipid HTO12 ≥98% 3047222-45-4 25mg $464 2026-04-30 Buy
Cayman Chemical 41202 Lipid HTO12 ≥98% 3047222-45-4 50mg $818 2026-04-30 Buy
BroadPharm bp-42661 Lipid HTO12 (solution in ethanol) 3047222-45-4 5MG $230 2026-05-24 Buy
Product number Packaging Price Buy
41202 5mg $109 Buy
41202 10mg $196 Buy
41202 25mg $464 Buy
41202 50mg $818 Buy
bp-42661 5MG $230 Buy

Lipid HTO12 Chemical Properties, Uses, Production

Description

Lipid HTO12 is an ionizable cationic lipid (pKa = 6.432) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.1 LNPs containing lipid HTO12 and encapsulating adenine base editor mRNA targeting Pcsk9 reduce hepatic Pcsk9 levels in mice at a reduced ionizable lipid/total lipids-to-mRNA ratio than LNPs containing SM-102 (Item No. 33474).WARNING This product is not for human or veterinary use.

References

[1] QIUBING CHEN. Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing.[J]. National Science Review, 2024, 11 6: nwae135. DOI: 10.1093/nsr/nwae135

Lipid HTO12 Preparation Products And Raw materials

Raw materials

Preparation Products

Lipid HTO12 Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
Shochem(Shanghai)Co.,Ltd +86-021-50800795 13816874662 info@shochem.com China 500 58
TargetMol 400-821-0310 15002144251 xuexiang.shao@tsbiochem.com China 29128 58
Lipid HTO12 3047222-45-4