Propargylamine
- CAS No.
- 2450-71-7
- Chemical Name:
- Propargylamine
- Synonyms
- Prop-2-yn-1-amine;2-PROPYNYLAMINE;2-propyn-1-amine;POTASSIUM TER-BUTOXIDE;Propargulamine;MONO-PROPARGYLAMINE;Propargylamin;Prop-2-ynylamine;2-PropynyL;AlkyneaMine
- CBNumber:
- CB9185137
- Molecular Formula:
- C3H5N
- Molecular Weight:
- 55.08
- MDL Number:
- MFCD00008198
- MOL File:
- 2450-71-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 84 °C |
|---|---|
| Density | 0.86 |
| refractive index |
n |
| Flash point | 39 °F |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform, Ethyl Acetate |
| form | Liquid |
| pka | 7.89±0.29(Predicted) |
| color | Clear colorless to yellow |
| Appearance | Colorless volatile liquid |
| Water Solubility | miscible |
| Sensitive | Air Sensitive |
| BRN | 773681 |
| Dielectric constant | 6.6500000000000004 |
| InChI | 1S/C3H5N/c1-2-3-4/h1H,3-4H2 |
| InChIKey | JKANAVGODYYCQF-UHFFFAOYSA-N |
| SMILES | NCC#C |
| CAS DataBase Reference | 2450-71-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| NIST Chemistry Reference | Propargylamine(2450-71-7) |
| EPA Substance Registry System | 2-Propyn-1-amine (2450-71-7) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H302-H310-H314 | |||||||||
| Precautionary statements | P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | F,T | |||||||||
| Risk Statements | 11-22-24-34 | |||||||||
| Safety Statements | 16-26-33-36/37/39-45-28A | |||||||||
| RIDADR | UN 1992 3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UK5250000 | |||||||||
| F | 3-8-10-34 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29211990 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 2 Dermal Acute Tox. 4 Oral Eye Dam. 1 Flam. Liq. 2 Skin Corr. 1B |
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| NFPA 704 |
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Propargylamine price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P50900 | Propargylamine 98% | 2450-71-7 | 1g | $39.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | P50900 | Propargylamine 98% | 2450-71-7 | 5g | $93.8 | 2026-04-30 | Buy |
| TCI Chemical | P0911 | Propargylamine >97.0%(GC) | 2450-71-7 | 5mL | $50 | 2026-04-30 | Buy |
| TCI Chemical | P0911 | Propargylamine >97.0%(GC) | 2450-71-7 | 25mL | $169 | 2026-04-30 | Buy |
| TRC | TRC-P762520-5G | Propargylamine | 2450-71-7 | 5g | $103 | 2026-06-03 | Buy |
Propargylamine Chemical Properties, Uses, Production
Synthesis
At room temperature, propargyl bromide (1.0 equiv) was added to a solution of amine (2.0 equiv) in dichloromethane (0.5 M). The resulting reaction mixture was stirred overnight, then extracted three times with dichloromethane. All organic layers were combined and washed with water and brine. The organic layers were dried over anhydrous sodium sulfate, filtered to remove the drying agent, and the filtrate was concentrated to dryness. The residue was purified by silica gel column chromatography (eluting with n-hexane/AcOEt) to obtain propargylamine.
Chemical Properties
clear colorless to yellow liquid
Uses
A useful intermediates in the preparation of drugs or pesticides.
Uses
Propargylamine is used in the synthesis of a chiral, a fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene. It acts as an intermediate in the production of drugs.
Uses
Synthesis of a chiral, fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene.
Enzyme inhibitor
This alkynyl amine HCCCH2–NH2 (FWfree-base = 55.08 g/mol), also known as propargylamine and 3-amino-1-propyne, is a toxic liquid that boils at 83°C. The water-soluble hydrochloride melts at 179-182°C. Target(s): aldehyde dehydrogenase; diamine oxidase, or amine oxidase [copper-containing]; glycine cleavage complex, or glycine synthase; and monoamine oxidase, or amine oxidase [flavin-containing].
Propargylamine Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Kingnord Industrial Limited | 0791-86493591 | jeff@kingnord.com | China | 43 | 57 |
| NanTong Chemistar Chemical Co.,Ltd | 025-52643182 13914798241; | doria@chemipioneer.com.cn | China | 54 | 62 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6039 18920764717 | sales@heowns.com | China | 24650 | 60 |
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Wuhan EnTai Technology Development Co,.Ltd | 86-27-82330560 | 2536851935@qq.com | China | 346 | 69 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
View Latest Price from Propargylamine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | PROPARGYLAMINE
2450-71-7
|
$75.00-100.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-08-20 | PROPARGYLAMINE
2450-71-7
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-06-18 | Propargylamine
2450-71-7
|
$1.50 | 1g | 99.0% Min | 10 Tons | Shaanxi Didu New Materials Co. Ltd |
-
- PROPARGYLAMINE
2450-71-7
- $75.00-100.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- PROPARGYLAMINE
2450-71-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Propargylamine
2450-71-7
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
