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Cyclohexyldiphenylphosphine

CAS No.
6372-42-5
Chemical Name:
Cyclohexyldiphenylphosphine
Synonyms
DIPHENYLCYCLOHEXYLPHOSPHINE;CYCLOHEXYLDI;Cyclohexyldiphenylphospine;whitextl;Phosphine, cycL;Cyclohexyldihenylphosphine;CYCLOHEXYLDIPHENYLPHOSPHINE;cyclohexyldiphenyl-phosphin;diphenylcyclohexylphosphino;DIPHENYLPHOSPHINOCYCLOHEXANE
CBNumber:
CB9196324
Molecular Formula:
C18H21P
Molecular Weight:
268.33
MDL Number:
MFCD00046360
MOL File:
6372-42-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:37:35

Cyclohexyldiphenylphosphine Properties

Melting point 58-62 °C(lit.)
Boiling point 374.0±11.0 °C(Predicted)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form Powder
color White
Water Solubility insoluble
Sensitive Air Sensitive
InChI InChI=1S/C18H21P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-2,4-7,10-13,18H,3,8-9,14-15H2
InChIKey ZXKWUYWWVSKKQZ-UHFFFAOYSA-N
SMILES P(C1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
CAS DataBase Reference 6372-42-5(CAS DataBase Reference)
EPA Substance Registry System Phosphine, cyclohexyldiphenyl- (6372-42-5)
UNSPSC Code 12352002
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE Eyeshields, Gloves, type N95 (US)
Risk Statements  36/37/38
Safety Statements  24/25
WGK Germany  3
RTECS  SY8387500
TSCA  No
HS Code  29319090
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

Cyclohexyldiphenylphosphine price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 510742 Cyclohexyldiphenylphosphine 6372-42-5 5g $130 2026-04-30 Buy
TCI Chemical C1429 Cyclohexyldiphenylphosphine >97.0%(GC) 6372-42-5 5g $68 2026-04-30 Buy
TCI Chemical C1429 Cyclohexyldiphenylphosphine >97.0%(GC) 6372-42-5 25g $231 2026-04-30 Buy
Strem Chemicals 15-0900 Cyclohexyldiphenylphosphine, 98% 98% 6372-42-5 1g $47 2026-04-30 Buy
Strem Chemicals 15-0900 Cyclohexyldiphenylphosphine, 98% 98% 6372-42-5 5g $174 2026-04-30 Buy
Product number Packaging Price Buy
510742 5g $130 Buy
C1429 5g $68 Buy
C1429 25g $231 Buy
15-0900 1g $47 Buy
15-0900 5g $174 Buy

Cyclohexyldiphenylphosphine Chemical Properties, Uses, Production

Description

Cyclohexyldiphenylphosphine is a chemical compound commonly used as a ligand in coordination chemistry and organometallic synthesis. It acts as a stabilizing agent and facilitates various catalytic reactions. This compound finds applications in pharmaceuticals, fine chemicals, and materials science industries. Cyclohexyldiphenylphosphine should be handled with caution as it may cause skin and eye irritation. It should be stored in a cool, well-ventilated area away from heat sources or open flames. Proper personal protective equipment (PPE) should be worn when handling this compound. Not for human consumption. Such as Silver(I) phosphine complexes were synthesized by a reaction of AgNO3, AgCl, and AgBr with cyclohexyl diphenylphosphine to produce 1:1, 1:2, or 1:3 molar ratios of new silver complexes[1].

Chemical Properties

white to light yellow crystal powde

Uses

suzuki reaction

Uses

Cyclohexyldiphenylphosphine is used as ligand in coupling reaction. It is also used as a medical intermediate.

Reactions

Cyclohexyldiphenylphosphine can undergo complexation reactions with common transition metals and can be used to catalyze a variety of organic transformation reactions including Suzuki coupling reactions and metal-catalyzed Michael addition reactions.

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings

References

[1] Naganagowda, Gadada et al. “Synthesis, crystal structure and spectral studies of silver(I) cyclohexyldiphenylphosphine complexes: towards the biological evaluation on malignant and non-malignant cells.” Journal of Coordination Chemistry 21 1 (2023): 0.

Cyclohexyldiphenylphosphine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 311)
Supplier Tel Email Country ProdList Advantage
Puyang Huicheng Electronic Material Co. Ltd. 0393-0393-8910800 15039333257 info@huichengchem.com China 588 64
Xinxiang Runyu Material Co., Ltd. 166-166-37336996 15690792173 chenxi.song@runvmat.com China 282 55
Henan Research New Material Co., Ltd. 86-18903931531 18903931628 sales036@researchvip.com China 180 58
BeiJing Greenchem Technology Co.,Ltd. 131-21959385 18804271668 chemrocking@bjgreenchem.com China 272 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 2355568890 sales@demochem.com China 2569 57

Related Questions

Ask a question
Q:What is the use of Cyclohexyldiphenylphosphine?Zora - Oct 17,2025
A:Cyclohexyldiphenylphosphine is a chemical compound commonly used as a ligand in coordination chemistry and organometallic synthesis. It facilitates various catalytic reactions through acting as a stabilizing agent.

View Latest Price from Cyclohexyldiphenylphosphine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cyclohexyldiphenylphosphine pictures 2026-09-17 Cyclohexyldiphenylphosphine
6372-42-5
1KG 99.0% 100kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Cyclohexyldiphenylphosphine   pictures 2026-08-07 Cyclohexyldiphenylphosphine
6372-42-5
$1.00 1KG 99% 20 tons Shaanxi Dideu Medichem Co. Ltd
Cyclohexyldiphenylphosphine pictures 2026-06-04 Cyclohexyldiphenylphosphine
6372-42-5
1Kg 98% 100kg Henan Research New Materials Co., Ltd.
cyclohexyldiphenyl-phosphin CYCLOHEXYLDIPHENYLPHOSPHINE DIPHENYLPHOSPHINOCYCLOHEXANE whitextl Cyclohexyldiphenylphosphine,98% DIPHENYLCYCLOHEXYLPHOSPHINE(PH2PCY) CYCLOHEXYLDIPHENYLPHOSPHINE (DPCP) Cyclohexyl-di(phenyl)phosphane (2,2-diphenylcyclohexyl)phosphine Cyclohexyldiphenylphosphine oxide 98% Cyclohexyldiphenylphosphine > Phosphine, cyclohexyldiphenyl- Phosphine, cycL High purity CAS 6372-42-5 Cyclohexyldiphenylphosphine in stock Cyclohexyldihenylphosphine diphenylcyclohexylphosphino CYCLOHEXYLDI Cyclohexyldiphenylphospine DIPHENYLCYCLOHEXYLPHOSPHINE 6372-42-5 C6H11C6H52P C18H21P C6H11PC6H52 Phosphorus Compounds Catalysis and Inorganic Chemistry Phosphine Ligands Achiral Phosphine Aryl Phosphine organophosphorus ligand Ligand Phosphine Ligands Synthetic Organic Chemistry Basic Phosphine LigandsCatalysis and Inorganic Chemistry Catalysis and Inorganic Chemistry Cross-Coupling Phosphine Ligands Phosphorus Compounds