Tricyclohexyl phosphine
- CAS No.
- 2622-14-2
- Chemical Name:
- Tricyclohexyl phosphine
- Synonyms
- PCY3;TRICYCLOHEXYLPHOSPHINE;Cy3P;TCHP;TricycL;Phosphine, tricyclohexyl-;NSC 158657;Protein TCHP;P(4-MeOC6H4)3;Tricyclohexyl phosph
- CBNumber:
- CB9251553
- Molecular Formula:
- C18H33P
- Molecular Weight:
- 280.43
- MDL Number:
- MFCD00003853
- MOL File:
- 2622-14-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Tricyclohexylphosphine | 261971 | 1g | $69.83 |
| Tricyclohexylphosphine 97% | 261971 | 5g | $86.5 |
| ANTI-TCHP (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | SAB1302957 | 400μL | $461 |
| Tricyclohexylphosphine, 97% | 15-6150 | 5g | $69 |
| Tricyclohexylphosphine, 97% | 15-6150 | 25g | $254 |
| More product size | |||
| Melting point | 81-83 °C (lit.) |
|---|---|
| Boiling point | 383.4±9.0 °C | Condition: Press: 760 Torr |
| Density | 0.909 g/mL at 25 °C |
| Flash point | 48 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly, Heated, Sonicaetd), Ethyl Acetate (Slightly) |
| form | Solution |
| color | White to off-white |
| Specific Gravity | 0.9 |
| Water Solubility | Soluble in most organic solvents. Insoluble in water. |
| Sensitive | Air Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 957171 |
| Stability | Air Sensitive, Moisture Sensitive |
| InChI | 1S/C18H33P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h16-18H,1-15H2 |
| InChIKey | WLPUWLXVBWGYMZ-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)P(C2CCCCC2)C3CCCCC3 |
| CAS DataBase Reference | 2622-14-2(CAS DataBase Reference) |
| FDA UNII | 34HJS55VCG |
| NIST Chemistry Reference | Phosphine, tricyclohexyl-(2622-14-2) |
| EPA Substance Registry System | Phosphine, tricyclohexyl- (2622-14-2) |
| UNSPSC Code | 12350000 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H304-H315-H319-H335-H336-H361d-H373-H412 | |||||||||
| Precautionary statements | P210-P273-P301+P310-P303+P361+P353-P305+P351+P338-P331 | |||||||||
| target organs | Central nervous system, Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,Xn,F | |||||||||
| Risk Statements | 36/37/38-22-37/38-36-19-11-67-65-63-48/20-40 | |||||||||
| Safety Statements | 26-36/37-62-37/39-36-33-29-16 | |||||||||
| RIDADR | UN 2056 3/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29319090 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Aquatic Chronic 3 Asp. Tox. 1 Eye Irrit. 2 Flam. Liq. 2 Repr. 2 Skin Irrit. 2 STOT RE 2 STOT SE 3 |
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| NFPA 704 |
|
Tricyclohexyl phosphine price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 261971 | Tricyclohexylphosphine | 2622-14-2 | 1g | $69.83 | 2025-07-31 | Buy |
| Sigma-Aldrich | 261971 | Tricyclohexylphosphine 97% | 2622-14-2 | 5g | $86.5 | 2025-07-31 | Buy |
| Sigma-Aldrich | SAB1302957 | ANTI-TCHP (CENTER) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 2622-14-2 | 400μL | $461 | 2023-01-07 | Buy |
| Strem Chemicals | 15-6150 | Tricyclohexylphosphine, 97% | 2622-14-2 | 5g | $69 | 2024-03-01 | Buy |
| Strem Chemicals | 15-6150 | Tricyclohexylphosphine, 97% | 2622-14-2 | 25g | $254 | 2024-03-01 | Buy |
Tricyclohexyl phosphine Chemical Properties,Uses,Production
Description
Tricyclohexyl phosphine is the tertiary phosphine with the formula P( C 6H11) 3. Commonly used as a ligand in organometallic chemistry, it is often abbreviated to PCy 3, where Cy stands for cyclohexyl. It is characterized by both high basicity (pK a = 9.7) and a large ligand cone angle (170°). Tricyclohexyl-phosphine is more basic (and so a better c-donor) than tribu tyiphosphine, which in turn is more basic than triphenyl phosphIne.
Chemical Properties
clear colorless to pale yellow solution
Uses
- Tricyclohexyl Phosphine is a ligand catalyst used primarily in organometallic chemistry.
- Ligand used in the Pd-catalyzed coupling of malononitrile with aryl halides.
- suzuki reaction: Bulky phosphine ligand used with a Pd(0)-triolefinic macrocycle catalyst for Suzuki coupling of aryl bromides and chlorides.
- This ligand is applied with Ni as a key intermediate in the formation of cylcopentane compounds.
- As a reagent, Tricyclohexylphosphine is used for a range of metal-catalyzed organic transformations.
- Crabtree's catalyst is an organoiridium compound containing tricyclohexyl phosphine used for hydrogenation of mono-, di-, tri-, and tetra- substituted substrates and hydrogen transfer reactions.
- Grubbs' catalysts consists of transition metal ruthenium and tricylohexyl phosphine utilized in olefin metathesis in synthetic organic chemistry.
Uses
Tricyclohexylphosphine is used as a ligand in organometallic chemistry. As a reagent, it is used for a range of metal-catalyzed organic transformations. Crabtree's catalyst is an organoiridium compound containing tricyclohexyl phosphine used for hydrogenation of mono-, di-, tri-, and tetra- substituted substrates and hydrogen transfer reactions. Grubbscatalysts consists of transition metal ruthenium and tricylohexyl phosphine utilized in olefin metathesis in synthetic organic chemistry.
reaction suitability
reaction type: Cross Couplings
reagent type: ligand
reaction type: Heck Reaction
reagent type: ligand
reaction type: Hiyama Coupling
reagent type: ligand
reaction type: Sonogashira Coupling
reagent type: ligand
reaction type: Suzuki-Miyaura Coupling
Synthesis
Triphenylphosphine oxide (1 mmol), dry n-hexane (1 mL) and complexed aluminum hydroxide reagent (1 mmol) were added to the Schlenk tube under nitrogen atmosphere and then the reaction was carried out with stirring at room temperature for 10 minutes. The completion of the reaction mixture was monitored by TLC spot plate and at the end of the reaction, the reaction mixture was filtered through silica gel and the reaction mixture was washed several times with ethyl acetate, the residue obtained from the evaporation of ethyl acetate was separated and purified by silica gel column chromatography using pure cyclohexane to obtain the tricyclohexylphosphine product.
Purification Methods
It recrystallises from EtOH [Boert et al. J Am Chem Soc 109 7781 1987]. [Beilstein 16 IV 947.]
Tricyclohexyl phosphine Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| XINXIANG RUNYU MATERIAL CO., LTD. | +86-13592593621; +8613592593621 | sales@runvmat.com | China | 446 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 | bj1@bj-chem.com | China | 299 | 55 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13799 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
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View Lastest Price from Tricyclohexyl phosphine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-23 | Tricyclohexyl phosphine
2622-14-2
|
US $0.00-0.00 / KG | 1KG | 0.99 | 500kg | XINXIANG RUNYU MATERIAL CO., LTD. | |
 |
2025-12-12 | Tricyclohexylphosphine
2622-14-2
|
US $1.00-0.00 / KG | 1KG | 99% | 20 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-12-01 | Tricyclohexyl phosphine
2622-14-2
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- Tricyclohexyl phosphine
2622-14-2
- US $0.00-0.00 / KG
- 0.99
- XINXIANG RUNYU MATERIAL CO., LTD.
-
- Tricyclohexylphosphine
2622-14-2
- US $1.00-0.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Tricyclohexyl phosphine
2622-14-2
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
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