2-(4-morpholinyl)-4-pyridinylamine
- CAS No.
- 35980-77-9
- Chemical Name:
- 2-(4-morpholinyl)-4-pyridinylamine
- Synonyms
- 2-Mrpholinopyridin-4-amine;2-Morpholinopyridin-4-aMine;2-MORPHOLIN-4-YLPYRIDIN-4-AMINE;4-Pyridinamine, 2-(4-morpholinyl)-;2-morpholin-4-yl-pyridin-4-ylamine;2-(4-morpholinyl)-4-pyridinylamine
- CBNumber:
- CB92032011
- Molecular Formula:
- C9H13N3O
- Molecular Weight:
- 179.22
- MDL Number:
- MFCD02945666
- MOL File:
- 35980-77-9.mol
- MSDS File:
- SDS
| Boiling point | 414.4±45.0 °C(Predicted) |
|---|---|
| Density | 1.208±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | solid |
| pka | 9.35±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | 1S/C9H13N3O/c10-8-1-2-11-9(7-8)12-3-5-13-6-4-12/h1-2,7H,3-6H2,(H2,10,11) |
| InChIKey | ZSXQDGMZXKOADT-UHFFFAOYSA-N |
| SMILES | Nc1ccnc(c1)N2CCOCC2 |
| UNSPSC Code | 12352116 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H302-H319-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | WGK 3 |
| HS Code | 2934999090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
2-(4-morpholinyl)-4-pyridinylamine price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR908236 | 2-Morpholinopyridin-4-amine 98% | 35980-77-9 | 100mg | $56 | 2026-06-04 | Buy |
| Apolloscientific | OR908236 | 2-Morpholinopyridin-4-amine 98% | 35980-77-9 | 250mg | $69 | 2026-06-04 | Buy |
| Apolloscientific | OR908236 | 2-Morpholinopyridin-4-amine 98% | 35980-77-9 | 1g | $179 | 2026-06-04 | Buy |
| Matrix Scientific | 293936 | 2-Morpholinopyridin-4-amine | 35980-77-9 | 250.00mg | $68 | 2026-05-19 | Buy |
| Matrix Scientific | 293936 | 2-Morpholinopyridin-4-amine | 35980-77-9 | 1.00g | $176 | 2026-05-19 | Buy |
2-(4-morpholinyl)-4-pyridinylamine Chemical Properties,Uses,Production
Synthesis
110-91-8
14432-12-3
35980-77-9
General procedure for the synthesis of 2-morpholin-4-aminopyridine from morpholine and 2-chloro-4-aminopyridine: 2-chloro-4-aminopyridine (5.0 g, 38.9 mmol) was suspended in aminomethanol (13 mL) and heated in a microwave reactor for 1 hr at 200 °C. Upon completion of the reaction, the mixture was cooled to room temperature and a precipitate was observed to be generated. Ether (45 mL) was added to the mixture, stirred for 10 minutes and filtered. The filter cake was washed with ether and dried to give the target product 2-morpholin-4-amine pyridine (6.61 g, 95% yield).
References
[1] Patent: WO2008/88881, 2008, A1. Location in patent: Page/Page column 51
[2] Angewandte Chemie - International Edition, 2018, vol. 57, # 34, p. 11035 - 11039
[3] Angew. Chem., 2018, vol. 130, # 34, p. 11201 - 11205,5
[4] Patent: US2005/65151, 2005, A1. Location in patent: Page/Page column 6; 14
[5] Patent: WO2017/93718, 2017, A1. Location in patent: Page/Page column 64
2-(4-morpholinyl)-4-pyridinylamine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Cantotech Chemicals, Ltd. | 86-0755-86635001 | cantotech@126.com | China | 4554 | 55 |
| Zhengzhou HSH Science & Technology Co., Ltd. | 0371-55932928 18937192232; | 1282296214@qq.com | China | 497 | 55 |
| Tianjin Olefin Pharmaceutical Co., Ltd. | 18202662021 18522876413 | 2781212171@qq.com | China | 313 | 56 |
| Zhengzhou TRIZ Pharmaceutical Technology Co., Ltd. | 19943855286 | 94644163@qq.com | China | 1934 | 56 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| Zhengzhou AiXi Technology Co., Ltd. | 0371-56787280 13137706083 | m18539565376@163.com | China | 999 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9699 | 58 |
