MMP substrate III, fluorogenic
- CAS No.
- 193475-71-7
- Chemical Name:
- MMP substrate III, fluorogenic
- Synonyms
- TNO211;MMP Substrate III;MMP substrate III, fluorogenic;DABCYL-GABA-PQGL-E(EDANS)-AK-NH2;DABCYL-(G-ABU)-PQGL-E(EDANS)AK-NH2;DABCYL-(γ-Abu)-PQGL-E(EDANS)AK-NH2;DABCYL-γ-Abu-PQGL-Glu(EDANS)-AK-NH2;490 MMP Substrate XVI (TNO211) - 1 mg;DABCYL-(GAMMA-ABU)-PQGL-E(EDANS)AK-NH2;DABCYL-GABA-PRO-GLN-GLY-LEU-GLU(EDANS)-ALA-LYS-NH2
- CBNumber:
- CB9211591
- Molecular Formula:
- C63H88N16O14S
- Molecular Weight:
- 1325.54
- MDL Number:
- MFCD02094711
- MOL File:
- 193475-71-7.mol
- TDS File:
- TDS
| Density | 1.40±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | -20°C |
| solubility |
DMSO: soluble Tris-buffered saline, pH 7.6: soluble |
| pka | -0.26±0.40(Predicted) |
| form | lyophilized solid |
| color | red |
| Sequence | {DABCYL-GABA}-Pro-Gln-Gly-Leu-Glu-{EDANS}-Ala-Lys-NH2 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
MMP substrate III, fluorogenic price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 444256 | MMP Substrate III, Fluorogenic A specific fluorogenic resonance energy transfer (FRET) peptide substrate with an MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencher combination. | 500μG | $398 | 2026-04-30 | Buy | |
| Biosynth | FD110965 | DABCYL-gamma-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 | 193475-71-7 | 500ug | $900 | 2026-06-04 | Buy |
| Biosynth | FD110965 | DABCYL-gamma-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 | 193475-71-7 | 250ug | $900 | 2026-06-04 | Buy |
| Biosynth | FD110965 | DABCYL-gamma-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 | 193475-71-7 | 100ug | $900 | 2026-06-04 | Buy |
| Biosynth | FD110965 | DABCYL-gamma-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 | 193475-71-7 | 1000ug | $1510 | 2026-06-04 | Buy |
MMP substrate III, fluorogenic Chemical Properties,Uses,Production
Uses
TNO211 is a biological active peptide. (Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.This peptide is a highly soluble fluorogenic MMP substrate for MMP-2, 8, 12, 13 and 14, containing the MMP cleavable Gly-Leu bond and EDANS/DABCYL. Fluorogenic assays using TNO211 are sensitive and can detect MMP activity in culture medium from endothelial cells and untreated synovial fluid from patients. Abs/Em = 340/490 nm.)
Biological Activity
Cell permeable: no', 'Primary Target
Detection of MMP activity', 'Product does not compete with ATP.', 'Reversible: no
MMP substrate III, fluorogenic Preparation Products And Raw materials
Raw materials
Preparation Products
MMP substrate III, fluorogenic Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 | ymbetter@glbiochem.com | China | 9981 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 | Caroline@youngshechem.com | China | 4725 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19087 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
