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ChemicalBook >> CAS DataBase List >>3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER Structure
3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER structure
CAS No.
23062-91-1
Chemical Name:
3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER
Synonyms
PD 102807;Ethyl 9-Methoxy-2-methyl-6a,11,12,14-tetrahydro-3H-indolo[4',5':5,6][1,3]oxazino[2,3-a]isoquinoline-1-carboxylate;Ethyl 9-methoxy-2-methyl-6a,11,12,14-tetrahydro-3H-indolo[4',5':5,6][1,3]oxazino[2,3-a]isoquinoline-1-carboxylate;3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1.2-b]pyrrolo[3.2-f][1.3]benzoxazine-1-carboxylicacidethyles];3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid ethyl ester;12H-Isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid, 3,6a,11,14-tetrahydro-9-methoxy-2-methyl-, ethyl ester;3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER
CBNumber:
CB9213373
Molecular Formula:
C23H24N2O4
Molecular Weight:
392.45
MDL Number:
MFCD04118313
MOL File:
23062-91-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 19:39:08
Product description Number Pack Size Price
PD 102807 462089 10mg $468
PD 102807 462089 25mg $758
PD 102807 Asreported 256177 10mg $480
PD 102807 Asreported 256177 50mg $1338
PD 102807 98.52% CS-0029049 5mg $162
Request For Quotation

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER Properties

Boiling point 586.0±50.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 100 mM in DMSO
form Powder
pka 15.77±0.20(Predicted)
color Off-white to light yellow
FDA UNII A7U96364HK

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 462089 PD 102807 23062-91-1 10mg $468 2026-06-03 Buy
Usbiological 462089 PD 102807 23062-91-1 25mg $758 2026-06-03 Buy
Usbiological 256177 PD 102807 Asreported 23062-91-1 10mg $480 2026-06-03 Buy
Usbiological 256177 PD 102807 Asreported 23062-91-1 50mg $1338 2026-06-03 Buy
ChemScene CS-0029049 PD 102807 98.52% 23062-91-1 5mg $162 2026-06-04 Buy
Product number Packaging Price Buy
462089 10mg $468 Buy
462089 25mg $758 Buy
256177 10mg $480 Buy
256177 50mg $1338 Buy
CS-0029049 5mg $162 Buy

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER Chemical Properties,Uses,Production

Uses

PD 102807 is a selective mAChR M4 antagonist.

Definition

ChEBI: LSM-1888 is an indolyl carboxylic acid.

Biological Activity

Selective M 4 muscarinic receptor antagonist. IC 50 values are 91, 6559, 3441, 950 and 7412 nM for human M 4 , M 1 , M 2 , M 3 , and M 5 receptors respectively.

in vivo

Striatal perfusion of PD-102807 (3 μM) alleviates levodopa-induced dyskinesia (LID) and inhibits nigral GABA and Glu along with striatal Glu release[3].

Animal Model:Male Sprague-Dawley rats[3]
Dosage:3 μM
Administration:Administration:Perfusion started 40 min prior to L-DOPA (6 mg/Kg plus 12 mg/Kg benserazide, s.c.) administration and continued until the end of experiment.
Result:Basal dialysate levels in PD-102807 experiment were 19.19±2.62 nM and 47.77±3.42 nM for GABA and Glu in SNr, respectively, and 41.38±4.25 nM for Glu in striatum.
Reduced global Axial Limb Orolingual (ALO) Abnormal Involuntary Movements (AIM) expression from 70.75±5.64 to 25.38±6.64, significantly attenuating limb, axial and orolingual AIMs at 3 μM.
Inhibited the L-DOPA-induced rise of substantia nigra pars reticulata (SNr) GABA, SNr Glu, and striatal Glu at 3 μM.

IC 50

mAChR4

storage

Room temperature

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER Suppliers

Global( 35)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15838 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89686 60
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44909 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10336 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
BOC Sciences 65
EMMX Biotechnology LLC 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Energy Chemical 58
MedBioPharmaceutical Technology Inc 58
cjbscvictory 58

View Lastest Price from 3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PD-102807 pictures 2026-05-11 PD-102807
23062-91-1
 $197.00 98.90% 10g TargetMol Chemicals Inc.
  • PD-102807 pictures
  • PD-102807
    23062-91-1
  • $197.00
  • 98.90%
  • TargetMol Chemicals Inc.

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER Spectrum

3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER(23062-91-1)1HNMR

23062-91-1(3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER)Related Search:

1H-INDOLE-4-METHANAMINE, N-ETHYL- 4-METHYLINDOLE-3-CARBOXALDEHYDE 5-METHOXY-4-METHYLINDOLE 1H-INDOLE-4-METHANAMINE, N-(PHENYLMETHYL)- 4-METHYLINDOLE-3-CARBOXYLIC ACID
4-AMINOMETHYLINDOLE 3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER 5-BENZYLOXY-1H-INDOLE-3-CARBOXYLIC ACID 1H-INDOLE-4-ETHANAMINE, N-METHYL- 5-BENZYLOXY-1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER
5-(Phenylmethoxy)-1H-indole-3-carbaldehyde

1of3

3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1.2-b]pyrrolo[3.2-f][1.3]benzoxazine-1-carboxylicacidethyles] 3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid ethyl ester 3,6A,11,14-TETRAHYDRO-9-METHOXY-2-METHYL-(12H)-ISOQUINO[1,2-B]PYRROLO[3,2-F][1,3]BENZOXAZINE-1-CARBOXYLIC ACID, ETHYL ESTER PD 102807 12H-Isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid, 3,6a,11,14-tetrahydro-9-methoxy-2-methyl-, ethyl ester Ethyl 9-methoxy-2-methyl-6a,11,12,14-tetrahydro-3H-indolo[4',5':5,6][1,3]oxazino[2,3-a]isoquinoline-1-carboxylate Ethyl 9-Methoxy-2-methyl-6a,11,12,14-tetrahydro-3H-indolo[4',5':5,6][1,3]oxazino[2,3-a]isoquinoline-1-carboxylate 23062-91-1 Acetylcholine receptor