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NF 023

CAS No.
104869-31-0
Chemical Name:
NF 023
Synonyms
NF 023;NF023 hexasodium;NF 023 hydrate;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt;8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT;8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT;8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate;8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt
CBNumber:
CB9220784
Molecular Formula:
C33H20N4Na6O19S6
Molecular Weight:
1106.86
MDL Number:
MFCD01074985
MOL File:
104869-31-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:20:27

NF 023 Properties

storage temp. Desiccate at RT
solubility H2O: >20 mg/mL
form crystalline
color white
Water Solubility Soluble to 100 mM in water
InChIKey FLINBQMOKZJBEC-UHFFFAOYSA-H
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

NF 023 price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N8652 NF 023 hydrate ≥98% (HPLC), solid 104869-31-0 10mg $205 2026-04-30 Buy
Sigma-Aldrich N8652 NF 023 hydrate ≥98% (HPLC), solid 104869-31-0 50mg $663 2026-04-30 Buy
Sigma-Aldrich 480415 NF023 A suramin analog that acts as a selective and direct G-protein antagonist for α-subunits of the Go/Gi group (EC?? ~ 300 nM). 10MG $311 2026-04-30 Buy
Cayman Chemical 17234 NF 023 (hydrate) ≥90% 1219024-70-0 1mg $42 2026-04-30 Buy
Cayman Chemical 17234 NF 023 (hydrate) ≥90% 1219024-70-0 5mg $137 2026-04-30 Buy
Product number Packaging Price Buy
N8652 10mg $205 Buy
N8652 50mg $663 Buy
480415 10MG $311 Buy
17234 1mg $42 Buy
17234 5mg $137 Buy

NF 023 Chemical Properties, Uses, Production

Uses

NF 023 is a subtype selective, competitive and reversible P2X1 receptor antagonist.

Biological Activity

A subtype-selective, competitive and reversible P2X 1 receptor antagonist. Displays IC 50 values of 0.21, 28.9, > 50 and > 100 μ M for human P2X 1 , P2X 3 , P2X 2 , and P2X 4 -mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also selectively inhibits the α -subunit of G o/i (EC 50 ~ 300 nM).

Biochem/physiol Actions

NF 023 contains six benzene rings and is a suramin analog. It is a potent, competitive, and selective P2X purinoceptor antagonist that aids in discriminating between P2X receptor subtypes.

storage

Desiccate at RT

NF 023 Preparation Products And Raw materials

Raw materials

Preparation Products

NF 023 Suppliers

Global Suppliers ( 60)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Beijing Minruida Technology Co., Ltd. 010-82387566 sales@mreda.com.cn China 19323 58
Chunchuang (Wuhan) Technology Co., Ltd 15727060112 yutianchun2007@126.com China 9869 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
NF 023 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE)]BIS-(1,3,5-NAPHTHALENETRISULFONIC ACID), 6NA 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENE CARBONYLIMINO)]BIS(1,3,5-NAPHTHALENE-TRISULFONIC ACID) HEXASODIUM SALT 8,8'-[CARBONYLBIS(IMINO-3,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENE-TRISULPHONIC ACID, HEXASODIUM SALT 8,8′-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hexasodium salt hydrate 8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt 8,8μ-[Carbonylbis(imino-3,1-phenylene carbonylimino)]bis(1,3,5-naphthalene-trisulfonic acid) hydrate hexasodium salt NF 023 hydrate 8,8'-[Carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt NF023 hexasodium 104869-31-0 C35H20N4Na6O21S6 C35H20N4O21S66Na BioChemical Cell Signaling and Neuroscience Cell Biology Ion Channels Ligand-Gated Ion Channels P2X Receptor Modulators Purinergics P2 receptor