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Iopromide

CAS No.
73334-07-3
Chemical Name:
Iopromide
Synonyms
Iopromid;Ultravist;1,3-benzenedicarboxamide,n,n’-bis(2,3-dihydroxypropyl)-5-((methoxyacetyl)amino;N1,N3-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N1-methylisophthalamide;shl414c;oproMide;ZK 35760;Proscope;IOPROMIDE;Iopromidum
CBNumber:
CB9236567
Molecular Formula:
C18H24I3N3O8
Molecular Weight:
791.11
MDL Number:
MFCD00867924
MOL File:
73334-07-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-01 20:51:29

Iopromide Properties

Melting point broad (160C transition)
Boiling point 840.9±65.0 °C(Predicted)
Density 2.173±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility Freely soluble in water and in dimethyl sulfoxide, practically insoluble in ethanol (96 per cent) and in acetone.
pka 10.62±0.70(Predicted)
form Solid
color White to off-white
Stability Hygroscopic
Major Application clinical
InChI InChI=1S/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29)
InChIKey DGAIEPBNLOQYER-UHFFFAOYSA-N
SMILES C1(C(N(CC(O)CO)C)=O)=C(I)C(NC(COC)=O)=C(I)C(C(NCC(O)CO)=O)=C1I
CAS DataBase Reference 73334-07-3(CAS DataBase Reference)
FDA UNII 712BAC33MZ
NCI Drug Dictionary iopromide
ATC code V08AB05
EPA Substance Registry System 1,3-Benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N1-methyl- (73334-07-3)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P391-P501
Hazard Codes  N
Risk Statements  50/53
Safety Statements  60-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  CZ2230000
HazardClass  9
HS Code  2924296000
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Acute 1
Aquatic Chronic 1
Toxicity LD50 in mice, rats (g iodine/kg body weight): 16.5, 11.4 i.v. (Muetzel)
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

Iopromide price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0001022 Iopromide for system suitability 2 European Pharmacopoeia (EP) Reference Standard 73334-07-3 5 mg $127 2026-04-30 Buy
Sigma-Aldrich Y0001021 Iopromide for system suitability 1 European Pharmacopoeia (EP) Reference Standard 73334-07-3 5 mg $127 2026-04-30 Buy
Sigma-Aldrich Y0001020 Iopromide European Pharmacopoeia (EP) Reference Standard 73334-07-3 100 mg $167 2026-04-30 Buy
Sigma-Aldrich 38701 Iopromide analytical standard 73334-07-3 25mg $528 2026-04-30 Buy
Sigma-Aldrich 1344804 Iopromide United States Pharmacopeia (USP) Reference Standard 73334-07-3 400mg $422 2026-04-30 Buy
Product number Packaging Price Buy
Y0001022 5 mg $127 Buy
Y0001021 5 mg $127 Buy
Y0001020 100 mg $167 Buy
38701 25mg $528 Buy
1344804 400mg $422 Buy

Iopromide Chemical Properties,Uses,Production

Description

Iopromide is a non-ionic, water-soluble X-ray contrast agent for intravascular administration. Iopromide can cause acute kidney injury and is used in animal models of contrast-induced nephropathy.

Chemical Properties

White Solid

Uses

Contrast molecule

Uses

Labelled Iopromide. Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).

Definition

ChEBI: A dicarboxylic acid diamide that consists of N-methylisophthalamide bearing three iodo substituents at positions 2, 4 and 6, a methoxyacetyl substituent at position 5 and two 2,3-dihydroxypropyl groups attached to the amide nitrogens. A ater soluble x-ray contrast agent for intravascular administration.

brand name

Ultravist (Berlex).

General Description

Iopromide is a low-osmolar,nonionic monomer with 48% bound iodine content. It is indicatedfor use in angiography, excretory urography, andnumerous CT procedures.

Side effects

Most common adverse reactions (>1%) are headache, nausea, injection site and infusion site reactions, vasodilatation, vomiting, back pain, urinary urgency, chest pain, pain, dysgeusia, and abnormal vision.

References

[1] YOUNG-HWAN AHN. The potential utility of iodinated contrast media (ICM) skin testing in patients with ICM hypersensitivity.[J]. Journal of Korean Medical Science, 2015, 30 3: 245-251. DOI: 10.3346/jkms.2015.30.3.245
[2] JIN-YONG PARK. A new micro-computed tomography-based high-resolution blood-brain barrier imaging technique to study ischemic stroke.[J]. Stroke, 2014, 45 8: 2480-2484. DOI: 10.1161/strokeaha.114.006297
[3] KAMAL HASSAN  Hassan F. Is hypoalbuminemia a prognostic risk factor for contrast-induced nephropathy in peritoneal dialysis patients[J]. Therapeutics and Clinical Risk Management, 2014, 10: 787-795. DOI: 10.2147/tcrm.s70665
[4] NA WANG. Renal Protective Effect of Probucol in Rats with Contrast-Induced Nephropathy and its Underlying Mechanism.[J]. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 2015: 2886-2892. DOI: 10.12659/msm.895543

1009809-16-8
73334-07-3
Synthesis of Iopromide from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-
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View Lastest Price from Iopromide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Iopromide pictures 2026-09-12 Iopromide
73334-07-3
0.99 RongNa Biotechnology Co.,Ltd
Iopromide  pictures 2026-09-11 Iopromide
73334-07-3
1g More Than 99% 100kg/Month BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
iopromide pictures 2026-09-03 iopromide
73334-07-3
1kg 99% 200ton/month Hangzhou multinpharma Co.,Ltd
  • Iopromide pictures
  • Iopromide
    73334-07-3
  • 0.99
  • RongNa Biotechnology Co.,Ltd
  • Iopromide  pictures
  • Iopromide
    73334-07-3
  • $0.00
  • More Than 99%
  • BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
  • iopromide pictures
  • iopromide
    73334-07-3
  • 99%
  • Hangzhou multinpharma Co.,Ltd
1,3-benzenedicarboxamide,n,n’-bis(2,3-dihydroxypropyl)-5-((methoxyacetyl)amino 6-triiodo-)-n-methyl-4 shl414c IOPROMIDE N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N'-methylbenzene-1,3-dicarboxamide Iopromide(mixture of isomers) Iopromid oproMide IoproMide SynonyMs: N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-Methoxyacetyl)aMino]-N'-Methylbenzene-1,3-dicarboxaMide Iopromide, >=98% magnesium methanide propan-1-ide(1:1:1) N1,N3-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N1-methylisophthalamide 1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl- Ultravist 300 Ultravist 370 ZK 35760 N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetylamino)-N-methylisophthalamide N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methyl-1,3-benzenedicarboxamide Proscope 1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-3-N-methylbenzene-1,3-dicarboxamide N,N'-diglyceryl-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N'-methyl-isophthalamide N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyethanoylamino)-N3-methyl-benzene-1,3-dicarboxamide Iopromide (400 mg) Iopromide for system suitability 1 CRS Iopromide CRS Iopromide, isomer mixture Iopromide for system suitability 2 CRS Iopromidum 1,3-Benzenedicarboxamide, N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(2-methoxyacetyl)amino]-N1-methyl- Iopromide USP/EP/BP Iopromide,≥99% N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-N1-methylbenzene-1,3-dicarboxamide IopromideQ: What is Iopromide Q: What is the CAS Number of Iopromide Q: What is the storage condition of Iopromide Q: What are the applications of Iopromide Iopromide (1344804) Iopromide (Mixture of Diastereomers) Iopromide, isomer mixture in water C14348600 Iopromid Iopromide 100 μg/ml Water Iopromide in Acetonitrile Ioprosamide Iopromide, 10 mM in DMSO Iopromid 100 μg/mL in Acetonitrile Ultravist iopromide material 73334-07-3 57-46-1 73334-07-1 C18H24I3N3O8 C18H21D3I3N3O8 Isotope Labelled Compounds Amines Aromatics Diagnostic Intermediates & Fine Chemicals Pharmaceuticals