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4-(Trimethylsilyl)-3-butyn-2-one

4-(Trimethylsilyl)-3-butyn-2-one Structure
4-(Trimethylsilyl)-3-butyn-2-one structure
CAS No.
5930-98-3
Chemical Name:
4-(Trimethylsilyl)-3-butyn-2-one
Synonyms
DKSI102;DKFELEX0334;TIMTEC-BB SBB009031;4-TRIMETHYLSILYL-3-BUTYN-2-ONE;4-trimethylsilylbut-3-yn-2-one;4-(Trimethysilyl)-3-butyn-2-one;4-TriMethylsilanyl-but-3-yn-2-one;4-(trimehtylsilyl)-3-Butyne-2-one;3-Butyn-2-one, 4-(trimethylsilyl)-;4-(TRIMETHYLSILYL)-3-BUTYN-2-ONE 98%
CBNumber:
CB9242865
Molecular Formula:
C7H12OSi
Molecular Weight:
140.26
MDL Number:
MFCD00190212
MOL File:
5930-98-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-09 15:12:03
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4-(Trimethylsilyl)-3-butyn-2-one Properties

Melting point 99 °C
Boiling point 156 °C(lit.)
Density 0.854 g/mL at 25 °C(lit.)
refractive index n20/D 1.442(lit.)
Flash point 83 °F
storage temp. Flammables area
form clear liquid
Specific Gravity 0.854
color Colorless to Light yellow to Light orange
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
InChI InChI=1S/C7H12OSi/c1-7(8)5-6-9(2,3)4/h1-4H3
InChIKey NQEZDDPEJMKMOS-UHFFFAOYSA-N
SMILES CC(=O)C#C[Si](C)(C)C
CAS DataBase Reference 5930-98-3(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P210-P233-P240-P241-P303+P361+P353-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  10-36/37/38
Safety Statements  16-26-36-37/39
RIDADR  UN 1224 3/PG 3
WGK Germany  3
HazardClass  3
PackingGroup  III
HS Code  29319090
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

4-(Trimethylsilyl)-3-butyn-2-one price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 418676 4-(Trimethylsilyl)-3-butyn-2-one 97% 5930-98-3 5g $101 2026-04-30 Buy
TCI Chemical T2973 4-(Trimethylsilyl)-3-butyn-2-one >97.0%(GC) 5930-98-3 5mL $72 2026-04-30 Buy
TCI Chemical T2973 4-(Trimethylsilyl)-3-butyn-2-one >97.0%(GC) 5930-98-3 25mL $247 2026-04-30 Buy
Apolloscientific OR932761 4-(Trimethylsilyl)-3-butyn-2-one >98% 5930-98-3 5g $21 2026-06-04 Buy
Apolloscientific OR932761 4-(Trimethylsilyl)-3-butyn-2-one >98% 5930-98-3 25g $93 2026-06-04 Buy
Product number Packaging Price Buy
418676 5g $101 Buy
T2973 5mL $72 Buy
T2973 25mL $247 Buy
OR932761 5g $21 Buy
OR932761 25g $93 Buy

4-(Trimethylsilyl)-3-butyn-2-one Chemical Properties, Uses, Production

Chemical Properties

clear slightly yellow liquid

Uses

4-(Trimethylsilyl)-3-butyn-2-one (TMSB) has been used to investigate its asymmetric bioreduction to (S)-4-(trimethylsilyl)-3-butyn-2-ol {(S)-TMSBOL} by employing biocompatible water-immiscible ionic liquids (ILs). TMSB may be used for the synthesis of entecavir (BMS-200475).

General Description

4-(Trimethylsilyl)-3-butyn-2-one is a ketone. Its asymmetric bioreduction to enantiopure {(S)-TMSBOL in various hydrophilic ionic liquid (ILs) solvent systems has been reported.

Synthesis

Equipped with a thermometer, spherical condenser tube (the upper end of the connection of anhydrous calcium chloride drying tube and then pass into the NaOH aqueous solution) in a 100 ml three-necked bottle, according to a certain charging method, in accordance with a certain proportion of bis (trimethylsilyl) acetylene and methanol added to the reaction bottle, and constantly pass into the nitrogen to open the reaction, when the temperature rises to 60 ~ 80 , began to add acetyl chloride droplets, reaction of the resulting HCI from the continuous passage of nitrogen brought out by the condensation tube, in the drying tube by NaOH aqueous solution absorption, titration is complete, and then continue to reflux for a certain period of time until the reaction temperature is no longer elevated, stop the reaction, the reaction device was quickly converted to a decompression distillation extracted half an hour of the gas for the exclusion of residual trace HCI gas, and then converted to atmospheric distillation of the reaction device to collect the fractions of 185 or so, that is, the final The target product 4-trimethylsilyl-3-butyn-2-one (content higher than 97%).

4-(Trimethylsilyl)-3-butyn-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

4-(Trimethylsilyl)-3-butyn-2-one Suppliers

Global Suppliers ( 199)
Supplier Tel Email Country ProdList Advantage
Shanghai Guijing New Material Technology Co., Ltd. 18616507986 2433448178@qq.com China 703 58
Syntechem Co.,Ltd. 519-88298820 15861130028 info@syntechem.com China 242 58
Shanghai Xx-lab New Materials Co., Ltd 13585834793 13660927110 xx_lab@126.com China 1429 58
Bengbu Chen Yixin Materials Technology Co., Ltd. 15655950695 15655950695 1608252589@qq.com China 498 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
New Energy Chemicals 0515-82159099 13770142076 info@njuchem.com China 251 65
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 0311-89250318 13582355795 master@sjzsdyn.com China 2776 65
Supplier Advantage
Shanghai Guijing New Material Technology Co., Ltd. 58
Syntechem Co.,Ltd. 58
Shanghai Xx-lab New Materials Co., Ltd 58
Bengbu Chen Yixin Materials Technology Co., Ltd. 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
New Energy Chemicals 65
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Shijiazhuang Sdyano Fine Chemical Co., Ltd. 65

View Latest Price from 4-(Trimethylsilyl)-3-butyn-2-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(Trimethylsilyl)-3-butyn-2-one pictures 2026-08-25 4-(Trimethylsilyl)-3-butyn-2-one
5930-98-3
 $3.00-9.00 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
4-(Trimethylsilyl)-3-butyn-2-one pictures 2026-07-10 4-(Trimethylsilyl)-3-butyn-2-one
5930-98-3
 1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
4-(Trimethylsilyl)-3-butyn-2-one pictures 2026-06-30 4-(Trimethylsilyl)-3-butyn-2-one
5930-98-3
 1KG 97.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

4-(Trimethylsilyl)-3-butyn-2-one Spectrum

4-(Trimethylsilyl)-3-butyn-2-one(5930-98-3)1HNMR

5930-98-3 (4-(Trimethylsilyl)-3-butyn-2-one) Related Search:

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4-trimethylsilylbut-3-yn-2-one 4-(Trimethylsilyl)-3-butyn-2-one,98% 4-(trimehtylsilyl)-3-Butyne-2-one 4-TriMethylsilanyl-but-3-yn-2-one 4-(TriMethylsilyl)-3-butyn-2-one, 98.0%(GC) 4-TRIMETHYLSILYL-3-BUTYN-2-ONE TIMTEC-BB SBB009031 4-(Trimethysilyl)-3-butyn-2-one 4-(TRIMETHYLSILYL)-3-BUTYN-2-ONE 98% 4-TRIMETHYLSILYL-3-BUTYN-2-ONE, 98%4-TRIMETHYLSILYL-3-BUTYN-2-ONE, 98%4-TRIMETHYLSILYL-3-BUTYN-2-ONE, 98% 3-Butyn-2-one, 4-(trimethylsilyl)- DKFELEX0334 DKSI102 5930-98-3 CH33SiC8801CCOCH3 CH33SiCCCOCH3 C7H12OSi Organic Building Blocks Internal Building Blocks Alkynes Internal Organic Building Blocks Alkynes