4-AMINO-6-NITRO-QUINALDINE
- CAS No.
- 99185-71-4
- Chemical Name:
- 4-AMINO-6-NITRO-QUINALDINE
- Synonyms
- 4-AMINO-6-NITRO-QUINALDINE;2-METHYL-6-NITROQUINOLIN-4-AMINE;4-amino-2-methyl-6-nitroquinoline;2-Methyl-4-aMino-6-nitroquinoline;4-Quinolinamine, 2-methyl-6-nitro-;2-Methyl-6-nitro-quinolin-4-ylaMine
- CBNumber:
- CB92464500
- Molecular Formula:
- C10H9N3O2
- Molecular Weight:
- 203.2
- MDL Number:
- MFCD09881395
- MOL File:
- 99185-71-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
4-AMINO-6-NITRO-QUINALDINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M350768 | 2-Methyl-6-nitroquinolin-4-amine | 99185-71-4 | 50mg | $90 | 2021-12-16 | Buy |
| AK Scientific | 0197CT | 2-Methyl-6-nitroquinolin-4-amine | 99185-71-4 | 100mg | $132 | 2021-12-16 | Buy |
| AK Scientific | 0197CT | 2-Methyl-6-nitroquinolin-4-amine | 99185-71-4 | 1g | $332 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0383370 | 4-QUINOLINAMINE, 2-METHYL-6-NITRO- 95.00% | 99185-71-4 | 5MG | $500.49 | 2021-12-16 | Buy |
| Alichem | 99185714 | 2-Methyl-6-nitroquinolin-4-amine | 99185-71-4 | 1g | $647.35 | 2021-12-16 | Buy |
4-AMINO-6-NITRO-QUINALDINE Chemical Properties,Uses,Production
Synthesis
1528735-22-9
99185-71-4
4-Azido-2-methyl-6-nitroquinoline (CAS:1528735-22-9; 29.9 g, 130 mmol) was used as starting material and suspended in THF (450 mL). Subsequently, triphenylphosphine (41.1 g, 160 mmol) was added to the suspension and the resulting mixture was stirred at room temperature for 20 min. Next, water (45 mL) was added and the reaction solution was concentrated to about 200 mL. The concentrated solution was poured into 2.5 M aqueous HCl (1.5 L) and stirred vigorously until the solid was completely dissolved. The aqueous phase was extracted with ether (250 mL x 3), followed by adjusting the pH of the aqueous phase with 50% NaOH aqueous solution to 9. The resulting bright yellow crystalline solid was collected by filtration, washed with cold water (500 mL), and dried to give 2-methyl-6-nitroquinolin-4-amine (25.2 g, 95% yield) as a bright yellow crystalline solid: melting point >250 °C; TLC Rf 0.37 ( Spreading agent ratio 95:4.5:0.5 CHCl3:MeOH:aqueous solution, MeNH2); 1H-NMR (DMSO-d6) δ 9.22 (d, 1H), 8.25 (dd, 1H), 7.77 (d, 1H), 7.30 (s, br, 2H), 6.55 (s, 1H), 2.45 (s, 3H).
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 1, p. 419 - 434
4-AMINO-6-NITRO-QUINALDINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 4004 | 55 |
| Changzhou Renaissance Chem Co. Ltd | 86-519-86202821 | China | 116 | 56 | |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5723 | 50 |
| Wuhan Greatwall chemical Co,.LTD | 400-027-6116 18086000087 | sales@chemgreatwall.com | China | 1559 | 55 |
| Changzhou Hopschain Chemical Co.,Ltd. | 0519-85528066 13775048983 | sales@hopschem.com | China | 31553 | 55 |
