Methyl 2-chloro-3-nitrobenzoate
- CAS No.
- 53553-14-3
- Chemical Name:
- Methyl 2-chloro-3-nitrobenzoate
- Synonyms
- Methyl 2-chloro-3-nitrobenzoate;Benzoic acid, 2-chloro-3-nitro-, methyl ester
- CBNumber:
- CB1382976
- Molecular Formula:
- C8H6ClNO4
- Molecular Weight:
- 215.59
- MDL Number:
- MFCD00482383
- MOL File:
- 53553-14-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| HS Code | 2916399090 |
Methyl 2-chloro-3-nitrobenzoate price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FC55358 | 2-Chloro-3-nitrobenzoic acid methyl ester | 53553-14-3 | 1g | $172.34 | 2026-06-04 | Buy |
| Biosynth | FC55358 | 2-Chloro-3-nitrobenzoic acid methyl ester | 53553-14-3 | 2g | $272.1 | 2026-06-04 | Buy |
| Biosynth | FC55358 | 2-Chloro-3-nitrobenzoic acid methyl ester | 53553-14-3 | 5g | $544.2 | 2026-06-04 | Buy |
| Biosynth | FC55358 | 2-Chloro-3-nitrobenzoic acid methyl ester | 53553-14-3 | 10g | $907.1 | 2026-06-04 | Buy |
| Biosynth | FC55358 | 2-Chloro-3-nitrobenzoic acid methyl ester | 53553-14-3 | 25g | $1814 | 2026-06-04 | Buy |
Methyl 2-chloro-3-nitrobenzoate Chemical Properties,Uses,Production
Uses
Methyl 2-Chloro-3-nitrobenzoate is a useful research chemical used in the preparation of benzothiadiazole derivatives as agrochemical microbicides.
Synthesis
67-56-1
3970-35-2
53553-14-3
General procedure for the synthesis of methyl 2-chloro-3-nitrobenzoate from methanol and 2-chloro-3-nitrobenzoic acid: 1. to a solution of 2-chloro-3-nitrobenzoic acid (10.0 g, 49.6 mmol) in methanol (80 mL) was added concentrated sulfuric acid (2.0 mL). 2. The reaction mixture was stirred overnight under reflux conditions. 3. Upon completion of the reaction, the methanol was removed by vacuum concentration. 4. Water was added to the residue and extracted with ethyl acetate. 5. The organic phase was washed sequentially with water, saturated sodium bicarbonate solution and saturated brine. 6. 6. The organic phase was dried with magnesium sulfate. 7. The target compound, methyl 2-chloro-3-nitrobenzoate (10.6 g, 99% yield), was obtained as a white solid by vacuum concentration. 8. The product was characterized by 1H NMR (CDCl3) and HPLC: 1H NMR (CDCl3) δ (ppm): 7.95 (dd, 1H), 7.84 (dd, 1H), 7.48 (t, 1H), 3.98 (s, 3H). HPLC Rt = 11.88 min. 150 × 6.0 mm); mobile phase: 0-20 min, acetonitrile/water = 10/90 to 100/0 (gradient), 20-30 min, acetonitrile/water = 100/0 (isocratic); flow rate: 1 mL/min.
References
[1] Patent: WO2008/51533, 2008, A2. Location in patent: Page/Page column 95
[2] Pesticide Science, 1997, vol. 50, # 4, p. 275 - 282
[3] Patent: EP1982982, 2008, A1. Location in patent: Page/Page column 197
[4] Patent: EP2141150, 2010, A1. Location in patent: Page/Page column 109-110
[5] Patent: KR101511396, 2015, B1. Location in patent: Paragraph 2881-2885
Methyl 2-chloro-3-nitrobenzoate Preparation Products And Raw materials
Methyl 2-chloro-3-nitrobenzoate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| NOTA Chemical (Shanghai) Co.,Ltd | 021-50189163 | sales@notachem.com | China | 208 | 64 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Moltt Biocem Co., Ltd. | +86-21-38682181 15900741819 | China | 281 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Modachem Shanghai Co., Ltd | +86 (0)21 51320687 51371369 1744605818 | China | 1576 | 58 | |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Changzhou Baokang Pharmaceutical & Chemical Co.,Ltd. | 0519-88787018 15261192718 | sales@baokangchem.com | China | 91 | 60 |
View Lastest Price from Methyl 2-chloro-3-nitrobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | METHYL 2-CHLORO-3-NITROBENZOATE
53553-14-3
|
1KG | 97.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
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- METHYL 2-CHLORO-3-NITROBENZOATE
53553-14-3
- 97.0%
- Shaanxi Dideu New Materials Co. Ltd
