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(R)-(+)-THALIDOMIDE

(R)-(+)-THALIDOMIDE structure

CAS No.: 2614-06-4

Chemical Name:: (R)-(+)-THALIDOMIDE

Synonyms: NSC 91729;(+)-Thalidomide;(R)-(+)-THALIDOMIDE;Thalidomide (R)-Isomer;6-dioxo-3-piperidyl)-n-(d-(+)-phthalimid;N-[(R)-2,6-Dioxopiperidine-3-yl]phthalimide;(+)-N-[(R)-2,6-Dioxo-3-piperidinyl]phthalimide;2-[(3R)-2,6-dioxopiperidin-3-yl]isoindole-1,3-dione;6-dioxo-3-piperidinyl)-3(2h)-dion(r)-1h-isoindole-2-(2;(3R)-3-(1,3-Dioxo-2H-isoindole-2-yl)piperidine-2,6-dione

CBNumber:: CB9251689

Molecular Formula:: C13H10N2O4

Molecular Weight:: 258.23

MDL Number:: MFCD00210220

MOL File:: 2614-06-4.mol

MSDS File:: SDS

Last updated:2026-04-14 09:55:04

Product description	Number	Pack Size	Price
(+)-Thalidomide ≥98%(HPLC),powder	T151	10mg	$142
(+)-Thalidomide ≥98%(HPLC),powder	T151	100mg	$910
(R)-(+)-Thalidomide	T338855	50mg	$495
(R)-(+)-THALIDOMIDE 95.00%	API0000090	5MG	$738.1
(R)-(+)-Thalidomide	13778	10mg	$490
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(R)-(+)-THALIDOMIDE Properties

Melting point	269-271°C
Boiling point	401.48°C (rough estimate)
Density	1.2944 (rough estimate)
refractive index	1.5300 (estimate)
storage temp.	-20°C Freezer
solubility	DMSO: soluble
pka	10.70±0.40(Predicted)
form	solid
color	white
InChI	1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)/t9-/m1/s1
InChIKey	UEJJHQNACJXSKW-SECBINFHSA-N
SMILES	O=C1CC[C@@H](N2C(=O)c3ccccc3C2=O)C(=O)N1
FDA UNII	QN61H68KLK
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Danger
Hazard statements	H302-H360
Precautionary statements	P201-P301+P312+P330-P308+P313
PPE	Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes	T
Risk Statements	61-22
Safety Statements	53-36/37/39-45
WGK Germany	3
RTECS	TI4925000
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 4 Oral Repr. 1B

(R)-(+)-THALIDOMIDE price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T151	(+)-Thalidomide ≥98%(HPLC),powder	2614-06-4	10mg	$142	2026-03-19	Buy
Sigma-Aldrich	T151	(+)-Thalidomide ≥98%(HPLC),powder	2614-06-4	100mg	$910	2026-03-19	Buy
TRC	T338855	(R)-(+)-Thalidomide	2614-06-4	50mg	$495	2021-12-16	Buy
American Custom Chemicals Corporation	API0000090	(R)-(+)-THALIDOMIDE 95.00%	2614-06-4	5MG	$738.1	2021-12-16	Buy
Medical Isotopes, Inc.	13778	(R)-(+)-Thalidomide	2614-06-4	10mg	$490	2021-12-16	Buy

Product number	Packaging	Price	Buy
T151	10mg	$142	Buy
T151	100mg	$910	Buy
T338855	50mg	$495	Buy
API0000090	5MG	$738.1	Buy
13778	10mg	$490	Buy

(R)-(+)-THALIDOMIDE Chemical Properties,Uses,Production

Chemical Properties

Needles

Uses

Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.

Uses

Thalidomide has been used to study its teratogenic effects in chicken embryos and human embryonic cells. This study reported that thalidomide causes limb defects by stabilizing PTEN, inhibiting the expression of Akt and activating caspase-dependent apoptosis. Thalidomide has also been used for studying glutathione mediated teratogenic resistance in mouse embryos.

Definition

ChEBI: A 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione that has R-configuration at the chiral centre.

reaction suitability

reagent type: ligand

Biochem/physiol Actions

(-)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor α (TNF-α). (R)-Thalidomide is called "safe enantiomer", but it can be converted in the body to (S)-isomer.

(R)-(+)-THALIDOMIDE synthesis

Synthesis of (R)-(+)-THALIDOMIDE from D-Ornithine monohydrochloride

(R)-(+)-THALIDOMIDE Preparation Products And Raw materials

Raw materials

Pentanedioic acid, 2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-, 1,5-dimethyl ester, (2S)- (-)-THALIDOMIDE Thalidomide N-PHTHALOYL-L-GLUTAMIC ACID N-Carbethoxyphthalimide

D-Ornithine monohydrochloride L-Glutamic acid Phthalic anhydride

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Preparation Products

(R)-(+)-THALIDOMIDE Suppliers

Global( 53)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39040	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53802	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15838	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7440	65
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	12952	65

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Chemsky（shanghai）International Co.,Ltd.	50
Daicel Chiral Technologies (China)CO.,LTD	65
BOC Sciences	65

View Lastest Price from (R)-(+)-THALIDOMIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-13	(R)-Thalidomide 2614-06-4	US $64.00-228.00 / mg		99.87%	10g	TargetMol Chemicals Inc.

(R)-Thalidomide
2614-06-4
US $64.00-228.00 / mg
99.87%
TargetMol Chemicals Inc.

(R)-(+)-THALIDOMIDE Spectrum

(R)-(+)-THALIDOMIDE(2614-06-4)¹HNMR

2614-06-4((R)-(+)-THALIDOMIDE)Related Search:

(-)-THALIDOMIDE >98% INHIBITOR OF ANGIOG EN,(S)-(-)-THALIDOMIDE (+-)-THALIDOMIDE >98% IMMUNOSUPPRESSIVE, SE,(+/-)-THALIDOMIDE,THALIDOMIDE,Thalidomide (soluble form) (R)-3-AMINOPIPERIDIN-2-ONE 3-amino-2-Piperidinone (R)-(+)-THALIDOMIDE

(R)-3-Aminopiperidine 3-AMINOPIPERIDINE Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). N-(piperidin-3-yl)benzamide 3-ACETAMIDOPIPERIDINE

3-DIMETHYLAMINOPIPERIDINE N-(2-AMINO-ETHYL)-PHTHALIMIDE THALIDOMIDE-D4 5'-HYDROXY THALIDOMIDE 3-(N-ACETYL-N-METHYLAMINO)PIPERIDINE

Thalidomide (+ and -) 2-(2-(3-azido-4-iodophenylpropionamido)ethoxy)thalidomide THALIDOMIDE UN2811-III

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(R)-2-(2,6-DIOXO-3-PIPERIDINYL)-1H-ISOINDOLE-1,3-(2H)-DIONE R-(+)-2-(2,6-DIOXO-3-PIPERIDINYL)-1H-ISOINDOLE-1,3(2H)-DIONE (R)-(+)-THALIDOMIDE 6-dioxo-3-piperidinyl)-3(2h)-dion(r)-1h-isoindole-2-(2 6-dioxo-3-piperidyl)-n-(d-(+)-phthalimid (+)-2-[(R)-2,6-Dioxo-3-piperidinyl]-1H-isoindole-1,3(2H)-dione (+)-N-[(R)-2,6-Dioxo-3-piperidinyl]phthalimide (3R)-3-(1,3-Dioxo-2H-isoindole-2-yl)piperidine-2,6-dione N-[(R)-2,6-Dioxopiperidine-3-yl]phthalimide NSC 91729 2-[(3R)-2,6-dioxopiperidin-3-yl]isoindole-1,3-dione Thalidomide (R)-Isomer 1H-Isoindole-1,3(2H)-dione, 2-[(3R)-2,6-dioxo-3-piperidinyl]- (+)-Thalidomide 2614-06-4 6/4/2614 2614-6-4 Angiogenesis Regulators BioChemical Cell Signaling and Neuroscience Cell Biology Extracellular Matrix Cytoskeleton and Extracellular Matrix Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals