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15-deoxy-Δ12,14-Prostaglandin A1

CAS No.
573951-20-9
Chemical Name:
15-deoxy-Δ12,14-Prostaglandin A1
Synonyms
LDOCIRJMPUHXRM-YUJGFSRTSA-N;15-deoxy-Δ12,14-Prostaglandin A1;15-deoxy-D12,14-Prostaglandin A1;Prosta-10,12,14-trien-1-oic acid, 9-oxo-, (12Z,14E)-;15-deoxy-δ12,14-Prostaglandin A1
CBNumber:
CB92589904
Molecular Formula:
C20H30O3
Molecular Weight:
318.45
MDL Number:
MFCD00797632
MOL File:
573951-20-9.mol
MSDS File:
SDS
Last updated:2026-05-28 05:57:02

15-deoxy-Δ12,14-Prostaglandin A1 Properties

solubility DMF: >75 mg/ml; DMSO: >50 mg/ml; Ethanol: >100 mg/ml; PBS (pH 7.2): >2.4 mg/ml

SAFETY

Risk and Safety Statements

15-deoxy-Δ12,14-Prostaglandin A1 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10065 15-deoxy-Δ12,14-Prostaglandin A1 ≥95% 573951-20-9 500μg $106 2026-04-30 Buy
Cayman Chemical 10065 15-deoxy-Δ12,14-Prostaglandin A1 ≥95% 573951-20-9 1mg $158 2026-04-30 Buy
Cayman Chemical 10065 15-deoxy-Δ12,14-Prostaglandin A1 ≥95% 573951-20-9 5mg $732 2026-04-30 Buy
ChemScene CS-0065196 15-Deoxy-Δ12,14-prostaglandin A1 573951-20-9 500??g $260 2026-06-04 Buy
ChemScene CS-0065196 15-Deoxy-Δ12,14-prostaglandin A1 573951-20-9 1mg $390 2026-06-04 Buy
Product number Packaging Price Buy
10065 500μg $106 Buy
10065 1mg $158 Buy
10065 5mg $732 Buy
CS-0065196 500??g $260 Buy
CS-0065196 1mg $390 Buy

15-deoxy-Δ12,14-Prostaglandin A1 Chemical Properties, Uses, Production

Description

15-deoxy-Δ12,14-Prostaglandin A1 (15-deoxy-Δ12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Δ12,14-PGJ2, which is a ligand for PPARγ. Antimitotic and antitumor activity have been reported for a similar analog, but there are no published reports on the biological activity of 15-deoxy-Δ12,14-PGA1 at this time.

Uses

15-Deoxy-Δ12,14-prostaglandin A1 is a deoxyanalog of prostaglandins that inhibits NF-κB signaling and induces apoptosis. 15-Deoxy-Δ12,14-prostaglandin A1 inhibits TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecule (CAM) and avoids monocyte arrest[1].

Definition

ChEBI: 15d-PGA1 is a prostanoid.

References

[1] Zernecke A, et al. Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction. FASEB J. 2003 Jun;17(9):1099-101. DOI:10.1096/fj.02-0485fje

15-deoxy-Δ12,14-Prostaglandin A1 Preparation Products And Raw materials

Raw materials

Preparation Products

15-deoxy-Δ12,14-Prostaglandin A1 Suppliers

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Jinan ponder chemical co. LTD 0531-0000 thinklifescience@163.com China 19684 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
15-deoxy-Δ12,14-Prostaglandin A1 15-deoxy-δ12,14-Prostaglandin A1 LDOCIRJMPUHXRM-YUJGFSRTSA-N Prosta-10,12,14-trien-1-oic acid, 9-oxo-, (12Z,14E)- 15-deoxy-D12,14-Prostaglandin A1 573951-20-9