2-Pyridin-2-yl-propan-2-ol
- CAS No.
- 37988-38-8
- Chemical Name:
- 2-Pyridin-2-yl-propan-2-ol
- Synonyms
- 2-(2-PYRIDYL)PROPAN-2-OL;2-(2-Pyridyl)-2-propanol;2-Pyridin-2-yl-propan-2-ol;1-PYRIDYL-1,1-DIMETHYLMETHANOL;2-(2-Hydroxyprop-2-yl)pyridine;a,a-diMethyl-2-PyridineMethanol;2-Pyridinemethanol, α,α-dimethyl-;2-(PYRIDINE-2-YL)PROPAN-2-OL,MIN.95%PYALC
- CBNumber:
- CB9260241
- Molecular Formula:
- C8H11NO
- Molecular Weight:
- 137.18
- MDL Number:
- MFCD00209259
- MOL File:
- 37988-38-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Note | Harmful |
| HS Code | 2933399990 |
2-Pyridin-2-yl-propan-2-ol price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Strem Chemicals | 07-3333 | 2-(Pyridine-2-yl)propan-2-ol, min. 95% pyalc min.95% | 37988-38-8 | 100mg | $60 | 2026-04-30 | Buy |
| Strem Chemicals | 07-3333 | 2-(Pyridine-2-yl)propan-2-ol, min. 95% pyalc min.95% | 37988-38-8 | 500mg | $233 | 2026-04-30 | Buy |
| Strem Chemicals | 07-3333 | 2-(Pyridine-2-yl)propan-2-ol, min. 95% pyalc min.95% | 37988-38-8 | 2g | $693 | 2026-04-30 | Buy |
| Apolloscientific | OR25562 | 2-(2-Hydroxyprop-2-yl)pyridine ≥95% | 37988-38-8 | 100mg | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR25562 | 2-(2-Hydroxyprop-2-yl)pyridine ≥95% | 37988-38-8 | 250mg | $41 | 2026-06-04 | Buy |
2-Pyridin-2-yl-propan-2-ol Chemical Properties, Uses, Production
Synthesis
91-02-1
917-54-4
37988-38-8
19490-92-7
Example 8. Synthesis of 2-(pyridin-2-yl)propan-2-ol (PyPrOH) and 1-phenyl-1-(pyridin-2-yl)ethanol (PPE). 2-Benzoylpyridine (8.3 mmol) was dissolved in dry ether (100 mL) in a 250 mL Schlenk flask that was pre-oven dried. The reaction system was cooled to -78°C, followed by the slow addition of methyl lithium (12.9 mL, 1.6 M ether solution) over 15 min. The resulting yellow solution was stirred at -78°C for 1 hour and then slowly warmed to room temperature. Upon completion of the reaction, the reaction was quenched by the addition of saturated aqueous ammonium chloride solution (30 mL) and the mixture was extracted with ethyl acetate (3 x 75 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was purified by fast column chromatography (silica gel, eluent ratio: 1:1 ethyl acetate/dichloromethane for PyPrOH, 1:3 ethyl acetate/dichloromethane for PPE) to give a light yellow, oily target product. 55% yield of PyPrOH was obtained.PyPrOH NMR Hydrogen spectrum (CDCl3, 300 MHz): δ 8.52 (d, J = 4.8 Hz , 1H), 7.71 (t, J = 7.8 Hz, 1H), 7.38 (d, J = 8.1 Hz, 1H), 7.21 (t, J = 6.2 Hz, 1H), 5.08 (s, 1H), 1.54 (s, 6H). 97% yield of PPE. NMR hydrogen spectrum of PPE (CDCl3, 300 MHz): δ 8.52 (m, 1H), 7.65 (td, J = 4.8 Hz), 1.54 (s, 6H). 7.65 (td, J = 7.8, 1.8 Hz, 1H), 7.48 (m, 2H), 7.31 (m, 3H), 7.17-7.26 (m, 2H), 5.85 (s, 1H), 1.94 (s, 3H).
References
[1] Patent: WO2014/200497, 2014, A1. Location in patent: Paragraph 00151
2-Pyridin-2-yl-propan-2-ol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Taifu Pharmaceutical Technology Co. LTD | 021-58111238 18930958102 | sales@taifupharm.com | China | 509 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Aikon International Limited | 025-58859352 13913916777 | dt3@aikonchem.com | China | 15490 | 58 |
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 9999 | 58 |
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