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IMiquiMod (hydrochloride)

IMiquiMod (hydrochloride) Structure
IMiquiMod (hydrochloride) structure
CAS No.
99011-78-6
Chemical Name:
IMiquiMod (hydrochloride)
Synonyms
Imiquimod HCl;IMiquiMod (hydrochloride);Imiquimod hydrochloride (R 837 hydrochloride);1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine hydrochloride;1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine hydrochloride , Imiquimod HCl
CBNumber:
CB92682005
Molecular Formula:
C14H17ClN4
Molecular Weight:
276.76458
MDL Number:
MFCD28168057
MOL File:
99011-78-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:07:24
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IMiquiMod (hydrochloride) Properties

Melting point >300 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility ≥3.59 mg/mL in EtOH with ultrasonic; ≥5.54 mg/mL in DMSO with gentle warming and ultrasonic; ≥7.34 mg/mL in H2O with ultrasonic
form solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

IMiquiMod (hydrochloride) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth ZDA01178 Imiquimod hydrochloride 99011-78-6 100mg $220 2026-06-05 Buy
Biosynth ZDA01178 Imiquimod hydrochloride 99011-78-6 250mg $345 2026-06-05 Buy
Biosynth ZDA01178 Imiquimod hydrochloride 99011-78-6 500mg $550 2026-06-05 Buy
Biosynth ZDA01178 Imiquimod hydrochloride 99011-78-6 1000mg $960 2026-06-05 Buy
ChemScene CS-2059 Imiquimod hydrochloride 99.75% 99011-78-6 100mg $65 2026-06-04 Buy
Product number Packaging Price Buy
ZDA01178 100mg $220 Buy
ZDA01178 250mg $345 Buy
ZDA01178 500mg $550 Buy
ZDA01178 1000mg $960 Buy
CS-2059 100mg $65 Buy

IMiquiMod (hydrochloride) Chemical Properties, Uses, Production

Uses

Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19[1][2].

Biological Activity

imiquimod hydrochloride is an immune response modifier that acts as a toll-like receptor 7 agonist and is commonly used topically to treat warts on the skin of the genital and anal areas.

in vivo

In animal models, Imiquimod hydrochloride stimulates the innate immune response by increasing NK cell activity, activating macrophages to secretecytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod hydrochloride stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumor necrosis factor (TNF)-α.

target

TLR7

HSV-1

IC 50

TLR7; HSV-1

References

[1] Athina Angelopoulou, et al. Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858. DOI:10.1016/j.envres.2020.109858
[2] Yuji Kan, et al. Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol. 2012 Oct;86(19):10338-46. DOI:10.1128/JVI.01196-12
[3] Aditya K Gupta, et al. Imiquimod: a review. J Cutan Med Surg. Nov-Dec 2002;6(6):554-60. DOI:10.1007/s10227-001-0134-6
[4] Michael P Schn, et al. The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol. 2006 Jun;126(6):1338-47. DOI:10.1038/sj.jid.5700286

IMiquiMod (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

IMiquiMod (hydrochloride) Suppliers

Global Suppliers ( 47)
Supplier Tel Email Country ProdList Advantage
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2308 55
Shanghai YuanYe Biotechnology Co., Ltd. 18916372613 yanzihan@shyuanye.com China 87240 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9784 58
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 28149 68
Zhengzhou Huiju Chemical Co., Ltd. 0371-55900031 18137872243 3927209986@qq.com China 9999 55
Heze Development Zone chuangli Chemical Co., Ltd. 0530-+86-530-529 6766，+86-15666160102 15666160102 info@chuangli-chem.com China 906 55
Musechem +1-800-259-7612 info@musechem.com United States 4648 60
Supplier Advantage
MedChemexpress LLC 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Pharmacodia (Beijing) Co.,Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62
Shanghai Chaolan Chemical Technology Center 58
Beijing Solarbio Science & Tecnology Co., Ltd. 68
Zhengzhou Huiju Chemical Co., Ltd. 55
Heze Development Zone chuangli Chemical Co., Ltd. 55
Musechem 60

IMiquiMod (hydrochloride) Spectrum

IMiquiMod (hydrochloride)(99011-78-6)1HNMR

99011-78-6 (IMiquiMod (hydrochloride)) Related Search:

1-Ethyl-1H-imidazo[4,5-c]quinolin-4-amine Imiquimod 2HCl IMiquiMod (Maleate) Imiquimod Imiquimod Related Compound D (25 mg) (1-Propyl-1H-imidazo[4,5-c]quinolin-4-amine)
1H-Imidazo[4,5-c]pyridin-4-amine, 1-(1-methylethyl)-

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IMiquiMod (hydrochloride) Imiquimod hydrochloride (R 837 hydrochloride) 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine hydrochloride 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine hydrochloride , Imiquimod HCl Imiquimod HCl 99011-78-6