(2R)-2-Aminopropanamide hydrochloride
- CAS No.
- 71810-97-4
- Chemical Name:
- (2R)-2-Aminopropanamide hydrochloride
- Synonyms
- H-D-ALA-NH2 HCL;D-ALANINAMIDE HYDROCHLORIDE;H-D-Ala-NH;D-Ala-NH2 HCl;D-AlaninamideHCl;D-ALANINEAMIDEHCL;D-ALANINE-NH2 HCL;Letermovir Impurity 19;H-D-Ala-NH2 hydrochloride;Safinamide Impurity SM3-E
- CBNumber:
- CB9268535
- Molecular Formula:
- C3H9ClN2O
- Molecular Weight:
- 124.57
- MDL Number:
- MFCD00039093
- MOL File:
- 71810-97-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 169 °C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in water or 1% acetic acid |
| form | Powder |
| color | White |
| Water Solubility | Soluble in 1% acetic acid and water. |
| InChI | InChI=1/C3H8N2O.ClH/c1-2(4)3(5)6;/h2H,4H2,1H3,(H2,5,6);1H/t2-;/s3 |
| InChIKey | FIAINKIUSZGVGX-NNUCSGGJNA-N |
| SMILES | [C@@H](N)(C)C(=O)N.Cl |&1:0,r| |
| CAS DataBase Reference | 71810-97-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 22-26-36/37/39 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 2922390090 | |||||||||
| NFPA 704 |
|
(2R)-2-Aminopropanamide hydrochloride price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 260564 | D-Alanine amide hydrochloride | 71810-97-4 | 5g | $333 | 2026-06-03 | Buy |
| Usbiological | 260564 | D-Alanine amide hydrochloride | 71810-97-4 | 10g | $460 | 2026-06-03 | Buy |
| Usbiological | 260564 | D-Alanine amide hydrochloride | 71810-97-4 | 25g | $692 | 2026-06-03 | Buy |
| Usbiological | 260564 | D-Alanine amide hydrochloride | 71810-97-4 | 50g | $1012 | 2026-06-03 | Buy |
| Usbiological | 260564 | D-Alanine amide hydrochloride | 71810-97-4 | 100g | $1414 | 2026-06-03 | Buy |
(2R)-2-Aminopropanamide hydrochloride Chemical Properties, Uses, Production
Uses
D-Alaninamide hydrochloride is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals.
Synthesis
1336-21-6
3744-87-4
541-41-3
71810-97-4
The general procedure for the synthesis of D-alaninamide hydrochloride from ammonia, (tert-butoxycarbonyl)alanine and ethyl chloroformate is as follows: 1. Boc-D-alanine (5.0 g, 26.43 mmol) was dissolved in anhydrous THF (100 mL). 2. triethylamine (4 mL, 2.91 g, 28.76 mmol) was added to the solution, followed by slow dropwise addition of ethyl chloroformate (2.5 mL, 2.951 g, 27.19 mmol). 3. The reaction mixture was placed in a carbon tetrachloride/dry ice cold bath with continuous stirring for about 30 minutes. 4. Concentrated ammonium hydroxide solution (5 mL, 74.0 mmol) was added, then the reaction mixture was transferred to a refrigerator and allowed to stand overnight. 5. Upon completion of the reaction, the solvent was removed by vacuum evaporation and the residue was dissolved in ethyl acetate. 6. The ethyl acetate layer was washed using saturated sodium carbonate solution and water, followed by drying the organic phase with anhydrous magnesium sulfate. 7. The desiccant was removed by filtration and the solvent was evaporated to obtain the crude product. 8. The crude product was treated with saturated hydrochloric acid/dioxane solution for 1 hour at room temperature. 9. The dioxane was removed by vacuum evaporation and the residue was dissolved in a small amount of methanol and precipitated by the addition of ether to give D-alaninamide hydrochloride (2.5 g, 76% yield).
References
[1] Patent: US5438118, 1995, A
(2R)-2-Aminopropanamide hydrochloride Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Xingcan Pharmaceutical Technology Co., Ltd. | 13594048950 19923294409 | xingcanyaoye@sina.com | China | 1590 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
View Latest Price from (2R)-2-Aminopropanamide hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | (2R)-2-Aminopropanamide hydrochloride
71810-97-4
|
1KG | 99% | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-08 | D-Alanine amide·hydrochloride salt
71810-97-4
|
1Box | 99% | 200kg | Hangzhou ICH Biofarm Co., Ltd | ||
 |
2024-01-08 | (2R)-2-Aminopropanamide hydrochloride
71810-97-4
|
$30.00-38.00 | 10kg | 99％ | 1000 | Wuhan Boyuan Import & Export Co., LTD |
-
- (2R)-2-Aminopropanamide hydrochloride
71810-97-4
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- D-Alanine amide·hydrochloride salt
71810-97-4
- $0.00
- 99%
- Hangzhou ICH Biofarm Co., Ltd
-
- (2R)-2-Aminopropanamide hydrochloride
71810-97-4
- $30.00-38.00
- 99％
- Wuhan Boyuan Import & Export Co., LTD
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