IBOGAINE
- CAS No.
- 83-74-9
- Chemical Name:
- IBOGAINE
- Synonyms
- Ibogain;IBOGAINE;endabuse;Ibogaine solution;12-Methoxyibogamine;12-methoxy-ibogamin;Ibogamine, 12-methoxy-;TIANFU CHEM-- IBOGAINE;IbogaineQ: What is Ibogaine Q: What is the CAS Number of Ibogaine;6,9-Methano-5H-pyrido[1',2':1,2]azepino[4,5-b]indole, ibogamine deriv.
- CBNumber:
- CB9300459
- Molecular Formula:
- C20H26N2O
- Molecular Weight:
- 310.43
- MDL Number:
- MFCD03265619
- MOL File:
- 83-74-9.mol
- MSDS File:
- SDS
| Melting point | 152-153° |
|---|---|
| alpha | D20 -53° (in 95% ethanol) |
| Boiling point | 450.59°C (rough estimate) |
| Density | 1.0633 (rough estimate) |
| refractive index | 1.6800 (estimate) |
| storage temp. | 2-8°C |
| pka | 8.1 in 80% methylcellosolve |
| Henry's Law Constant | 8.2×105 mol/(m3Pa) at 25℃, HSDB (2015) |
| EWG's Food Scores | 1 |
| FDA UNII | 3S814I130U |
| EPA Substance Registry System | Ibogaine (83-74-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | 1544 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Hazardous Substances Data | 83-74-9(Hazardous Substances Data) |
IBOGAINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FI159190 | Ibogaine | 83-74-9 | 5mg | $312.5 | 2026-06-04 | Buy |
| Biosynth | FI159190 | Ibogaine | 83-74-9 | 10mg | $562.5 | 2026-06-04 | Buy |
| Biosynth | FI159190 | Ibogaine | 83-74-9 | 25mg | $1093.75 | 2026-06-04 | Buy |
| Biosynth | FI159190 | Ibogaine | 83-74-9 | 50mg | $2062.5 | 2026-06-04 | Buy |
| Biosynth | FI159190 | Ibogaine | 83-74-9 | 100mg | $3750 | 2026-06-04 | Buy |
IBOGAINE Chemical Properties,Uses,Production
Description
This indole alkaloid occurs in the root of Tabernanthe iboga Baill. It was first
examined in detail by Raymond-Hamet who assigned to it the empirical formula
C19H24(26)ON2, now altered to that given above. The base forms colourless
crystals from EtOH and is laevorotatory with [Q1D - 53° (EtOH). It is insoluble
in Et20, slightly so in Me2CO or CHC1 3 but dissolves freely in MeOH, EtOH or
H20. The alkaloid yields a hydrochloride, m.p. 299°C (dec.); lQlhs - 67°
(MeOH) or - 37.3° (H20). It contains one methoxyl group and gives the typical
indole reactions. On distillation with Zn dust or soda-lime it furnishes products
which are indole derivatives with the ~-position free.
In a manner similar to that of cocaine, the alkaloid potentiates the pressor
action of adrenaline and abolishes the sino-carotid reflexes. Unlike cocaine,
however, it also augments the action of tyramine and that of dl-ephedrine to a
slight extent. Vincent and Sero have reported that it inhibits the action of serum
cholinesterase.
Definition
ChEBI: Ibogaine is an organic heteropentacyclic compound that is ibogamine in which the indole hydrogen para to the indole nitrogen has been replaced by a methoxy group. It has a role as a plant metabolite, an inhibitor, a hallucinogen and a oneirogen. It is a monoterpenoid indole alkaloid, an organic heteropentacyclic compound and an aromatic ether. It is functionally related to an ibogamine. It is a conjugate base of an ibogaine(1+).
Purification Methods
Crystallise it from EtOH or aqueous EtOH and sublime it at 150o/0.01mm. It is soluble in organic solvents but insoluble in H2O. The hydrochloride, m 299-300o(dec), is soluble in H2O and alcohols. [Büchi et al. J Am Chem Soc 88 3099 1866, Rosenmund Chem Ber 108 1871 1975, Beilstein 23 III/IV 2742.]
References
Raymond-Hamet., Bull. Soc. Chirn. Fr., 9,620 (1942)
Delourme-Houde., Chern. Abstr., 41, 1390 (1947)
Bartlett, Dickel, Taylor.,J. Arner. Chern. Soc., 80, 126 (1958)
Arai, Coppola, Jeffery., Acta Cryst., 13, 553 (1960)
Shamma, Soyster., Experientia, 20,36 (1964)
Synthesis:
Buchi et ai., f. Arner. Chern. Soc., 88,3099 (1966)
Pharmacology:
Raymond-Hamet, Rothlin., C.R. Soc. Bioi., 127,592 (1938)
Raymond-Hamet, Rothlin., Arch. inst. Pharrnacodyn., 63, 27 (1939)
Raymond-Hamet., Cornpt. rend., 201,285 (1940)
Raymond-Hamet., C.R. Soc. Bioi., 135, 176 (1941)
Raymond-Hamet, Perrot., Bull. Acad. Med., 24,423 (1941)
Vincent, Sero., C.R. Soc. Bioi., 136,612 (1942)
IBOGAINE Preparation Products And Raw materials
Raw materials
Preparation Products
IBOGAINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1490 | 55 | |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9413 | 50 | |
| ALB Technology Limited | 702-983-3769 | sales@albtechnology.com | United States | 2992 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
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