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2-Methyl-4-isothiazolin-3-one hydrochloride

2-Methyl-4-isothiazolin-3-one hydrochloride Structure
2-Methyl-4-isothiazolin-3-one hydrochloride structure
CAS No.
26172-54-3
Chemical Name:
2-Methyl-4-isothiazolin-3-one hydrochloride
Synonyms
2-METHYL-4-ISOTHIAZOLIN-3-ONE HCL;2-Methylisothiazol-3-one hydrochloride;2-methyl-2H-isothiazol-3-one hydrochloride;3(2H)-Isothiazolone,2-methyl-,hydrochloride;KB-838;MIT·HCL;MIT HYDROCHLORIDE;ISO-THIAZOLINONE(KATHON);N-MethylisothiazoloneHCl;2-Methylisothiazol-3(2H)
CBNumber:
CB9302514
Molecular Formula:
C4H6ClNOS
Molecular Weight:
151.61
MDL Number:
MFCD06804636
MOL File:
26172-54-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-16 21:18:09
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2-Methyl-4-isothiazolin-3-one hydrochloride Properties

Melting point 165-170°
Density 1.551 at 21℃
vapor pressure 0.777-1Pa at 20-25℃
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
BRN 3993054
Stability Hygroscopic
Major Application microbiology
InChI InChI=1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H
InChIKey SJXPQSRCFCPWQQ-UHFFFAOYSA-N
SMILES O=C1C=CSN1C.Cl
LogP -0.44 at 20℃ and pH2
Surface tension 71.3mN/m at 1g/L and 20℃
CAS DataBase Reference 26172-54-3(CAS DataBase Reference)
FDA UNII 3G9PNZ5P41
EPA Substance Registry System 3(2H)-Isothiazolone, 2-methyl-, hydrochloride (26172-54-3)
UNSPSC Code 51102829
NACRES NA.76

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)Environment (GHS09)
GHS05,GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H314-H317-H410
Precautionary statements  P260-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  C
Risk Statements  34-42/43
Safety Statements  26-36/37/39-45
RIDADR  UN 1759 8/PG 2
WGK Germany  3
TSCA  TSCA listed
HazardClass  8, 6.1
HS Code  2934100090
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Corr. 1A
Skin Sens. 1
REACH Registrations Active
Excepted Quantities Not Permitted as Excepted Quantity

2-Methyl-4-isothiazolin-3-one hydrochloride price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SBR00032 MIT HCl Ready Made Solution, (125-130 mg MIT HCl/mL in water) 50 mL $72.9 2026-04-30 Buy
Sigma-Aldrich SBR00032 MIT HCl Ready Made Solution, (125-130 mg MIT HCl/mL in water) 400 mL $566 2026-04-30 Buy
Sigma-Aldrich M6045 2-Methyl-4-isothiazolin-3-one hydrochloride ≥99% 26172-54-3 1g $166 2026-04-30 Buy
Sigma-Aldrich M6045 2-Methyl-4-isothiazolin-3-one hydrochloride ≥99% 26172-54-3 5g $562 2026-04-30 Buy
Usbiological 159692 2-Methyl-4-isothiazolin-3-one Hydrochloride (MIT) Asreported 26172-54-3 5g $638 2026-06-03 Buy
Product number Packaging Price Buy
SBR00032 50 mL $72.9 Buy
SBR00032 400 mL $566 Buy
M6045 1g $166 Buy
M6045 5g $562 Buy
159692 5g $638 Buy

2-Methyl-4-isothiazolin-3-one hydrochloride Chemical Properties, Uses, Production

Uses

2-Methyl-4-isothiazolin-3-one Hydrochloride is an isothiazolinone based biocide and preservative used in personal care products. It is also implicated as an allergen. It is also used for controlling microbial growth in water-containing solution.

Application

Methylisothiazolinone (MIT) has been used:
as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites

General Description

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a derivative of the synthetic isothiazolinone.

Biochem/physiol Actions

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth.

storage

store at 2°C - 8°C,close container well.

2-Methyl-4-isothiazolin-3-one hydrochloride synthesis

7791-25-5
1002-19-3
26172-54-3
Synthesis of 2-Methyl-4-isothiazolin-3-one hydrochloride from Sulfuryl chloride and 3-[(3-Amino-3-oxopropyl)dithio]propanamide

2-Methyl-4-isothiazolin-3-one hydrochloride Preparation Products And Raw materials

Raw materials

3-[(3-Amino-3-oxopropyl)dithio]propanamide Sulfuryl chloride

Preparation Products

2-Methyl-4-isothiazolin-3-one hydrochloride Suppliers

Global Suppliers ( 134)
Supplier Tel Email Country ProdList Advantage
Suzhou Laing Biological Technology Co., LTD 0512-62968256 18550502935 export@laingbiotec.com China 994 58
Shanghai Yiji Chemical Co.,Ltd. 021-22810390-339 13916710504 421877690@qq.com China 17 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9643 60
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
UHN Shanghai Research & Development Co., Ltd. 021-58958002 18930822973 sales@uhnshanghai.com China 997 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9331 58
Supplier Advantage
Suzhou Laing Biological Technology Co., LTD 58
Shanghai Yiji Chemical Co.,Ltd. 58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
Spectrum Chemical Manufacturing Corp. 60
Hangzhou Sage Chemical Co., Ltd. 58
UHN Shanghai Research & Development Co., Ltd. 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Guangzhou Isun Pharmaceutical Co., Ltd 55
Finetech Industry Limited 58

View Latest Price from 2-Methyl-4-isothiazolin-3-one hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Methyl-4-isothiazolin-3-one hydrochloride pictures 2026-09-16 2-Methyl-4-isothiazolin-3-one hydrochloride
26172-54-3
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2-Methyl-4-isothiazolin-3-one hydrochloride pictures 2026-09-14 2-Methyl-4-isothiazolin-3-one hydrochloride
26172-54-3
 1Kg/Drum 99% 300tons WUXI HONOR SHINE CHEMICAL CO.,LTD
2-Methyl-4-isothiazolin-3-one hydrochloride pictures 2026-06-30 2-Methyl-4-isothiazolin-3-one hydrochloride
26172-54-3
 1KG 99% 1000kgs Shaanxi Dideu New Materials Co. Ltd

2-Methyl-4-isothiazolin-3-one hydrochloride Spectrum

2-Methyl-4-isothiazolin-3-one hydrochloride(26172-54-3)1HNMR

26172-54-3 (2-Methyl-4-isothiazolin-3-one hydrochloride) Related Search:

Methyl acrylate Methylparaben Paraquat dichloride Basic Violet 1 5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
Methanol Topotecan hydrochloride Kresoxim-methyl 2-Methyl-4-isothiazolin-3-one Acetonitrile
Pyrrolidone hydrotribromide Methyl 5-Chloro-2-methyl-2H-isothiazol-3-one hydrochloride 4,5-Dichloro-2-octyl-isothiazolone Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)
Isothiazole 5-Chloro-2-methyl-4-isothiazolin-3-one Hydrochloric acid

1of4

MIT HYDROCHLORIDE 2-METHYL-4-ISOTHIAZOLIN-3-ONE HYDROCHLORIDE N-MethylisothiazoloneHCl ISO-THIAZOLINONE(KATHON) 2-METHYLISOTHIAZOLONE (MIT) HCL, 99+% 2-Methyl-3-isothiazolone Hydrochloride 2-Methyl-4-isothiazolin-3-one hydrochloride,MIT 2-Methyl-4-isothiazolin-3-on hydrochloride 2-Methyl-4-isothiazolin-3-one hydrochloride ((Isothiazolinone)) Methylisothiazolinone hydrochloride 2-METHYL-4-ISOTHIAZOLIN-3-ONE HYDRO& 2-Methylisothiazol-3(2H) 2-methyl-3(2h)-isothiazolonhydrochloride 2-Methylisothiazol-3(2H)-one hydrochloride MIT·HCL 2-Methyl-3-isothiazolone Hydrochloride Discontinued See M314985 3(2H)-Isothiazolone, 2-methyl-, hydrochloride (1:1) Methylisothiazolinone HCl N-Methylisothiazolin-3-one KB-838 2-Methylisothiazol-3-one hydrochloride 2-methyl-2H-isothiazol-3-one hydrochloride 2-METHYL-4-ISOTHIAZOLIN-3-ONE HCL 3(2H)-Isothiazolone,2-methyl-,hydrochloride 26172-54-3 C4H5NOSClH C4H5NOSHCl C4H6ClNOSC4H5NOSHCl BioChemical Antibiotics Antibiotics A to Z Antibiotics G-M Amines Heterocycles Sulfur & Selenium Compounds