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Mal-PEG6-NHS ester

CAS No.
1599472-25-9
Chemical Name:
Mal-PEG6-NHS ester
Synonyms
Mal-PEG6-NHS ester;Mal-PEG6-CH2CH2COONHS;Mal-PEG6-NHS ester ,S0630;2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate;4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber:
CB93062545
Molecular Formula:
C23H34N2O12
Molecular Weight:
530.52
MDL Number:
MFCD20926374
MOL File:
1599472-25-9.mol
MSDS File:
SDS
Last updated:2026-07-16 07:06:08

Mal-PEG6-NHS ester Properties

Boiling point 635.8±65.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DCM
pka -2.34±0.20(Predicted)
form Liquid
color Colorless to light yellow
InChI InChI=1S/C23H34N2O12/c26-19-1-2-20(27)24(19)6-8-32-10-12-34-14-16-36-18-17-35-15-13-33-11-9-31-7-5-23(30)37-25-21(28)3-4-22(25)29/h1-2H,3-18H2
InChIKey UUNUCVXNAHYFJP-UHFFFAOYSA-N
SMILES C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Mal-PEG6-NHS ester price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth ZNC47225 Mal-PEG6-NHS 1599472-25-9 250mg $1115 2026-06-05 Buy
Biosynth ZNC47225 Mal-PEG6-NHS 1599472-25-9 500mg $1550 2026-06-05 Buy
ChemScene CS-0104984 Mal-PEG6-NHS ester ≥95% 1599472-25-9 100mg $99 2026-06-04 Buy
ChemScene CS-0104984 Mal-PEG6-NHS ester ≥95% 1599472-25-9 250mg $180 2026-06-04 Buy
ChemScene CS-0104984 Mal-PEG6-NHS ester ≥95% 1599472-25-9 1g $510 2026-06-04 Buy
Product number Packaging Price Buy
ZNC47225 250mg $1115 Buy
ZNC47225 500mg $1550 Buy
CS-0104984 100mg $99 Buy
CS-0104984 250mg $180 Buy
CS-0104984 1g $510 Buy

Mal-PEG6-NHS ester Chemical Properties, Uses, Production

Description

Mal-PEG6-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.

IC 50

Non-cleavable Linker

References

[1] Kennett Sproge , et al. Relaxin prodrugs. WO2015067791A1.

Mal-PEG6-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 73)
Supplier Tel Email Country ProdList Advantage
Suzhou Highfine Biotech Co., Ltd 0512-69209928 18796809688 zhouyingxiang@highfine.com China 1846 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Hunan HuaTeng Pharmaceutical Co., Ltd., 400-8592883 15367835770 sales@huatengsci.com China 5869 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Borenpharm Co., Ltd 027-65563561 sales@borenpharm.com China 1245 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-55629727 13323845623 2885676761@qq.com China 9957 58
Amatek Scientific Co. Ltd. 0512-56316828 400-867-5858;400-867-5858 info@amateksci.com China 28760 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58

View Latest Price from Mal-PEG6-NHS ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mal-PEG6-NHS ester pictures 2026-07-15 Mal-PEG6-NHS ester
1599472-25-9
$31.00 10g TargetMol Chemicals Inc.
Mal-PEG6-NHS ester pictures 2025-06-07 Mal-PEG6-NHS ester
1599472-25-9
1g >98.00% 1g Xian confluore Biological Technology Co., Ltd.
2,5-dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate Mal-PEG6-NHS ester 4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-, 2,5-dioxo-1-pyrrolidinyl ester Mal-PEG6-CH2CH2COONHS Mal-PEG6-NHS ester ,S0630 1599472-25-9 peg