ChemicalBook >> CAS DataBase List >>Mal-PEG6-COOH

Mal-PEG6-COOH

CAS No.
1334177-79-5
Chemical Name:
Mal-PEG6-COOH
Synonyms
1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22-hexaoxa-4-azapentacosan-25-oic acid;Mal-PEG6-COOH;BMPA-PEG6-Acid;MAL dPEG6-acid;Mal-NH-PEG6-COOH;MAL-amido-PEG6-PA;MALEIMIDE-NH-PEG6-;MAL-AMIDO-PEG6-COOH;Mal-amido-PEG6-acid;Amido Mal-PEG6-Acid
CBNumber:
CB72603837
Molecular Formula:
C22H36N2O11
Molecular Weight:
504.53
MDL Number:
MFCD21363276
MOL File:
1334177-79-5.mol
MSDS File:
SDS
Last updated:2026-05-28 04:58:15

Mal-PEG6-COOH Properties

Boiling point 702.5±60.0 °C(Predicted)
Density 1.241±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
pka 4.28±0.10(Predicted)
form Solid
color Off-white to gray
InChI InChI=1S/C22H36N2O11/c25-19(3-6-24-20(26)1-2-21(24)27)23-5-8-31-10-12-33-14-16-35-18-17-34-15-13-32-11-9-30-7-4-22(28)29/h1-2H,3-18H2,(H,23,25)(H,28,29)
InChIKey WKTGEZMXNNBFEZ-UHFFFAOYSA-N
SMILES C(O)(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Mal-PEG6-COOH price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FM73023 Mal-PEG6-COOH 1334177-79-5 50mg $250 2026-06-04 Buy
Biosynth FM73023 Mal-PEG6-COOH 1334177-79-5 25mg $250 2026-06-04 Buy
Biosynth FM73023 Mal-PEG6-COOH 1334177-79-5 100mg $276 2026-06-04 Buy
Biosynth FM73023 Mal-PEG6-COOH 1334177-79-5 250mg $555 2026-06-04 Buy
Biosynth FM73023 Mal-PEG6-COOH 1334177-79-5 500mg $970 2026-06-04 Buy
Product number Packaging Price Buy
FM73023 50mg $250 Buy
FM73023 25mg $250 Buy
FM73023 100mg $276 Buy
FM73023 250mg $555 Buy
FM73023 500mg $970 Buy

Mal-PEG6-COOH Chemical Properties, Uses, Production

Description

Mal-amido-PEG6-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-amido-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG6-COOH Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 72)
Supplier Tel Email Country ProdList Advantage
Wanxin Biotechnology (Jiaxing) Co., LTD 0573-83568680 18057391398 3956524501@qq.com China 1441 58
Zhejiang Rui 'ao Biological Technology Co.,LTD. 82087565 15757883359 yan@ruiaochem.cn China 712 58
ChemPep, Inc. +1 (888) 615-9178 / (561) 791-8787 service@chempep.com United States 2138 57
Chengdu Pukang Biotechnology Co., Ltd 18217049878 cassie.gao@pu-kang.com China 480 58
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD. 21-33585366 13311639313 sales@shyrchem.com China 807 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Hunan HuaTeng Pharmaceutical Co., Ltd., 400-8592883 15367835770 sales@huatengsci.com China 5869 58
Shanghai Boka-chem Tech. Inc. 400-026-1533/(021) 6478-0600 sales@bokachem.com China 876 58
Tongling HengYou Biotechnology Co., Ltd. 021-50426030 13856289449;13124863828 2630597085@qq.com China 1885 55

View Latest Price from Mal-PEG6-COOH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mal-amido-PEG6-acid pictures 2026-05-11 Mal-amido-PEG6-acid
1334177-79-5
10g TargetMol Chemicals Inc.
Mal-NH-PEG6-CH2CH2COOH pictures 2026-01-29 Mal-NH-PEG6-CH2CH2COOH
1334177-79-5
1g 98% 300kg LAURENT
Mal-amido-PEG6-acid pictures 2025-06-07 Mal-amido-PEG6-acid
1334177-79-5
1g >98.00% 1g Xian confluore Biological Technology Co., Ltd.

Mal-PEG6-COOH Spectrum

MaleiMide-NH-PEG6-CH2CH2COOH Mal-amido-PEG6-acid Maleimide-PEG6-propionic acid MAL-AMIDO-PEG6-COOH Mal-NH-PEG6-COOH Mal-PEG6-COOH MALEIMIDE-NH-PEG6- 4,7,10,13,16,19-Hexaoxa-22-azapentacosanoic acid, 25-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo- Mal-amido-PEG6-propionic acid MAL dPEG6-acid BMPA-PEG6-Acid Mal-CH2CH2CONH-PEG6-CH2CH2COOH MAL-dPEG??-acid (QBD-10065) MAL-amido-PEG6-PA Amido Mal-PEG6-Acid 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22-hexaoxa-4-azapentacosan-25-oic acid Maleimide-PEG6-COOH 1334177-79-5 C22H36N2O11 Heterobifunctional PEG peg