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RS 102221 hydrochloride

RS 102221 hydrochloride structure

CAS No.: 185376-97-0

Chemical Name:: RS 102221 hydrochloride

Synonyms: RS 102221;RS102221HCl;RS 102221 hydrochlor;RS 102221 hydrochloride;4-dione hydrochloride hydrate;RS-102221 hydrochloride hydrate;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2;8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dionehy;N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide

CBNumber:: CB9312416

Molecular Formula:: C27H31F3N4O7S

Molecular Weight:: 612.62

MDL Number:: MFCD09971036

MOL File:: 185376-97-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:56:22

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RS 102221 hydrochloride Properties

Density	1.45
storage temp.	Store at RT
solubility	DMSO: ≥20mg/mL
form	powder
color	white
InChIKey	IGACJTZTAQBWKN-UHFFFAOYSA-N
SMILES	O.Cl.COc1cc(OC)c(cc1NS(=O)(=O)c2ccc(cc2)C(F)(F)F)C(=O)CCCCN3CCC4(CC3)NC(=O)NC4=O
FDA UNII	48D22QR8GY
UNSPSC Code	12352202

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
target organs	Respiratory system
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
WGK Germany	3
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

RS 102221 hydrochloride price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA00AE69	RS 102221 HYDROCHLORIDE 95%	185376-97-0	100mg	$607	2026-05-28	Buy
aablocks	AA00AE69	RS 102221 HYDROCHLORIDE 95%	185376-97-0	250mg	$992	2026-05-28	Buy
Tocris	1050	RS102221hydrochloride ≥98%(HPLC)	185376-97-0	10	$195	2021-12-16	Buy
Tocris	1050	RS102221hydrochloride ≥98%(HPLC)	185376-97-0	50	$818	2021-12-16	Buy
American Custom Chemicals Corporation	API0006966	RS-102221 95.00%	185376-97-0	10MG	$709.46	2021-12-16	Buy

Product number	Packaging	Price	Buy
AA00AE69	100mg	$607	Buy
AA00AE69	250mg	$992	Buy
1050	10	$195	Buy
1050	50	$818	Buy
API0006966	10MG	$709.46	Buy

RS 102221 hydrochloride Chemical Properties, Uses, Production

Uses

RS 102221 Hydrochloride is a selective 5-HT2C receptor antagonist.

Definition

ChEBI: N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide is an aromatic ketone.

Biological Activity

Potent and selective 5-HT 2C antagonist (pK i = 8.7). Displays ~ 100-fold selectivity over the 5-HT 2A and 5-HT 2B subtypes and is > 100-fold selective over other 5-HT receptors, a- and b-adrenergic and muscarinic ACh receptors.

RS 102221 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

RS 102221 hydrochloride Suppliers

Global Suppliers ( 19)

Supplier	Tel	Email	Country	ProdList	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
LETOPHARM LIMITED	+86-21-5821 5861	sales@letopharm.com	China	2374	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	9792	55
Amatek Scientific Co. Ltd.	0512-56316828 400-867-5858;400-867-5858	info@amateksci.com	China	28760	58
Jinan ponder chemical co. LTD	0531-0000	thinklifescience@163.com	China	19684	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	27626	58
Shanghai Universal Biotech Co.,Ltd	15921930842 15921930842	yh-wang@univ-bio.com	China	25030	58
Aikon International Limited	17714375163	hywu@aikonchem.com	China	9974	58

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
LETOPHARM LIMITED	58
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Amatek Scientific Co. Ltd.	58
Jinan ponder chemical co. LTD	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
Shanghai Universal Biotech Co.,Ltd	58
Aikon International Limited	58

185376-97-0 (RS 102221 hydrochloride) Related Search:

5-Methanesulphonamido-2-hydroxyacetophenone 1,3,8-Triaza-spiro[4.5]decane-2,4-dione RS 102221 hydrochloride N-(5-Acetyl-2-hydroxy-phenyl)-methanesulfonamide Puerarin

DL-4-Chlorophenylalanine methyl ester hydrochloride

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8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2,4-dionehy RS102221HCl 8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulfonamido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4. 8-[5-(2,4-Dimethoxy-5-(4-Trifluoromethylphenylsulphonamido)Phenyl-5-Oxopentyl)]-1,3,8-Triazaspiro[4.5]Decane-2,4-Dione Hydrochloride 8-[5-(2,4-DIMETHOXY-5-(4-TRIFLUOROMETHYLPHENYLSULPHONAMIDO)PHENYL-5-OXOPENTYL)]-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE HYDROCHLORIDE N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)benzenesulfonamide RS 102221 4-dione hydrochloride hydrate 8-[5-(2,4-Dimethoxy-5-(4-trifluoromethylphenylsulphonam ido)phenyl-5-oxopentyl]-1,3,8-triazaspiro[4.5]decane-2 RS-102221 hydrochloride hydrate Benzenesulfonamide, N-[5-[5-(2,4-dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)- RS 102221 hydrochlor RS 102221 hydrochloride 185376-97-0 C27H31F3N4O7S C27H32ClF3N4O7S C27H31F3N4O7SHCl