1,5-Dihydroxyanthraquinone
- CAS No.
- 117-12-4
- Chemical Name:
- 1,5-Dihydroxyanthraquinone
- Synonyms
- 1,5-dihydroxyanthracene-9,10-dione;ANTHRARUFIN;C14H8O4;NSC 7211;NSC 646570;Anthrarufin,80%;Anthrarufin 85%;Anthrarufin >1,5 DIHYDROXY AQ;RARECHEM AQ BD AN24
- CBNumber:
- CB9317976
- Molecular Formula:
- C14H8O4
- Molecular Weight:
- 240.21
- MDL Number:
- MFCD00001210
- MOL File:
- 117-12-4.mol
- MSDS File:
- SDS
| Melting point | 279 °C (dec.)(lit.) |
|---|---|
| Boiling point | 342.92°C (rough estimate) |
| Density | 1.56 g/cm3 |
| vapor density | 8.3 (vs air) |
| refractive index | 1.5430 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | Poor solubility in all solvents tested.DMSO (Sparingly) |
| form | Solid |
| pka | 6.42±0.20(Predicted) |
| color | Yellow to Green |
| Merck | 14,689 |
| BRN | 1881718 |
| InChI | InChI=1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)8-4-2-6-10(16)12(8)13(7)17/h1-6,15-16H |
| InChIKey | JPICKYUTICNNNJ-UHFFFAOYSA-N |
| SMILES | C1(O)=C2C(C(=O)C3=C(C2=O)C=CC=C3O)=CC=C1 |
| CAS DataBase Reference | 117-12-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | KPB60W5S3M |
| EPA Substance Registry System | Anthrarufin (117-12-4) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CB6630000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29146990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1,5-Dihydroxyanthraquinone price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 340014 | Anthrarufin technical grade, 85% | 117-12-4 | 100g | $168 | 2026-04-30 | Buy |
| TCI Chemical | D0562 | Anthrarufin >85.0%(HPLC) | 117-12-4 | 25g | $45 | 2026-04-30 | Buy |
| TCI Chemical | D0562 | Anthrarufin >85.0%(HPLC) | 117-12-4 | 500g | $161 | 2022-04-27 | Buy |
| Usbiological | 002784 | Anthrarufin ≥85% | 117-12-4 | 2.5g | $531 | 2026-06-03 | Buy |
| Biosynth | FD40719 | 1,5-Dihydroxyanthraquinone | 117-12-4 | 100g | $222 | 2026-06-04 | Buy |
1,5-Dihydroxyanthraquinone Chemical Properties, Uses, Production
Chemical Properties
Yellow to Green Solid
Uses
1,5-Dihydroxyanthraquinone is an anthraquinone derivative with suppressive effects against nitric oxide (NO) synthase. Potential antimalarial agent. Used in studies as a potential competitive non-peptidic inhibitor of HIV-1 protei nase.
Uses
Important intermediate in the manufacture of alizarin and indanthrene dyestuffs. Forms insoluble Ba and Ca lakes; has been proposed as analytical reagent for the detection of Ca.
Uses
1,5-Dihydroxyanthraquinone (anthrarufin) is an important intermediate for manufacturing disperse blue dyes. It is the key intermediates for manufacturing disperse blue dyes via dinitrodihydroxyanthraquinone and vat dyes via diaminoanthraquinones.
Definition
ChEBI: A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 5.
Synthesis
1,5-Dihydroxyanthraquinone is prepared from 1,5-anthraquinonedisulfonic acid by replacing the SO3H groups, and from 1,5-dinitroanthraquinone by directly replacing the nitro groups, e.g., in sulfolane with calcium oxide or, more effectively, via 1,5- dimethoxyanthraquinone and subsequent hydrolysis of the ether linkage.
Purification Methods
Purify anthrarufin by column chromatography on silica gel with CHCl3/Et2O as eluent, followed by recrystallisation from acetone. Alternatively recrystallise it from glacial acetic acid [Flom & Barbara J Phys Chem 89 4489 1985]. [Beilstein 7 III 2359, 8 IV 3268.]
1,5-Dihydroxyanthraquinone Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Xinliheng Chemical Co., Ltd | 13164644252 | 188819218@QQ.com | China | 904 | 58 |
| Hubei Chusheng Chemical Co., Ltd. | 027-87891008 18971624303 | 1569406342@qq.com | China | 262 | 58 |
| Henan yingchuang | 16650708709 | hnyingchuang@163.com | China | 3973 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
View Latest Price from 1,5-Dihydroxyanthraquinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 1,5-dihydroxyanthraquinone
117-12-4
|
20kg | 99% | 20 tons | Qingdao RENAS Polymer Material Co., Ltd. | ||
 |
2026-03-20 | 1,5-DIHYDROXYANTHRAQUINONE
117-12-4
|
$20.00 | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-04-15 | 1,5-DIHYDROXYANTHRAQUINONE
117-12-4
|
$10.00 | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
-
- 1,5-dihydroxyanthraquinone
117-12-4
- $0.00
- 99%
- Qingdao RENAS Polymer Material Co., Ltd.
-
- 1,5-DIHYDROXYANTHRAQUINONE
117-12-4
- $20.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1,5-DIHYDROXYANTHRAQUINONE
117-12-4
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
