ChemicalBook >> CAS DataBase List >>6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER

CAS No.
92557-81-8
Chemical Name:
6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER
Synonyms
6-FAM-NHS;6-FAM, SE;5/6-FAM-OSu;6-FAM SE (Green);6-FAM SE, 6-CF SE;6-FAM-SEor6-FAM-NHS;6-CARBOXYFLUORESCEIN SE;6-FAM SE, 10 mM in DMSO;6-CARBOXYFLUORESCEIN-NHS;-xanthene]-6-carboxylate
CBNumber:
CB9334911
Molecular Formula:
C25H15NO9
Molecular Weight:
473.39
MDL Number:
MFCD00077323
MOL File:
92557-81-8.mol
Last updated:2025-09-12 14:32:05
Product description Number Pack Size Price
6-Carboxyfluorescein-N-hydroxysuccinimideEster C178355 100mg $760
6-Carboxyfluorescein-N-hydroxysuccinimide ester 267964 10mg $446
6-FAM,SE ≥98.00% 240605 5g $2500
6-Carboxyfluorescein N-hydroxysuccinimide ester 95+% 093435 250mg $908
6-FAMN-succinimidylester ≥98%(HPLC) CDX-C0017-M100 100mg $988
More product size

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER Properties

Melting point >168°C (dec.)
Boiling point 788.1±70.0 °C(Predicted)
Density 1.74±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in N,N-dimethylformamide,dimethyl sulfoxide
pka 9.31 ± 0.20, most acidic, temperature:25 °C
form Solid
color Orange solid
Appearance Yellow solid
ex/em 492/517 nm
ε(extinction coefficient) 74,000 L⋅mol−1⋅cm−1
Φ(quantum yield) 0.93
λmax 496 nm (Buffer pH9)
Stability Moisture Sensitive
Biological Applications Analyzing aminoglycosides; analyzing/determining gabapentin; detecting/analyzing baclofen in human plasma at micromolar level; determining phosphorus-containing amino acid herbicides; multiplex genetic analysis; visualizing/detecting proteins; for synthesizing vancomycin analogs, vasopressin analogs; as a substrate for measuring kinase activity, phosphatase activity.
InChI InChI=1S/C25H15NO9/c27-13-2-5-16-19(10-13)33-20-11-14(28)3-6-17(20)25(16)18-9-12(1-4-15(18)24(32)34-25)23(31)35-26-21(29)7-8-22(26)30/h1-6,9-11,27-28H,7-8H2
InChIKey VDABVNMGKGUPEY-UHFFFAOYSA-N
SMILES C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC(C(ON3C(=O)CCC3=O)=O)=C1)C(=O)O2
CAS DataBase Reference 92557-81-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3
8-10-21
HS Code  29252900

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C178355 6-Carboxyfluorescein-N-hydroxysuccinimideEster 92557-81-8 100mg $760 2021-12-16 Buy
Usbiological 267964 6-Carboxyfluorescein-N-hydroxysuccinimide ester 92557-81-8 10mg $446 2021-12-16 Buy
ChemPep 240605 6-FAM,SE ≥98.00% 92557-81-8 5g $2500 2021-12-16 Buy
Matrix Scientific 093435 6-Carboxyfluorescein N-hydroxysuccinimide ester 95+% 92557-81-8 250mg $908 2021-12-16 Buy
Adipogen Life Sciences CDX-C0017-M100 6-FAMN-succinimidylester ≥98%(HPLC) 92557-81-8 100mg $988 2021-12-16 Buy
Product number Packaging Price Buy
C178355 100mg $760 Buy
267964 10mg $446 Buy
240605 5g $2500 Buy
093435 250mg $908 Buy
CDX-C0017-M100 100mg $988 Buy

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER Chemical Properties,Uses,Production

Description

Fluorescein (FAM) is a bright fluorophore that has found an extremely wide application in life science research. The fluorophore is hydrophilic and its derivatives possess good solubility in aqueous buffers.


Fluorescein is compatible with a wide variety of fluorescent instrumentation - most instruments are equipped with FAM channel filters.


This product contains the pure 6-isomer of fluorescein.

Chemical Properties

Yellow to orange powder

Uses

(6-FAM-SE) 6-Carboxyfluorescein-N-hydroxysuccinimide Ester is a commonly used fluorescent reagent for the labelling of peptides, proteins and nucleotides.

Uses

Intracellular pH probe. Fluorescent label for amines and alcohols.

Definition

ChEBI: 6-carboxyfluorescein succinimidyl ester is an N-hydroxysuccinimide ester derived from 6-carboxyfluorescein. A fluorescent cell staining dye, it is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably to intracellular lysine residues. It has a role as a fluorochrome. It is functionally related to a fluorescein (lactone form).

Abs/Em Maxima

492/517 nm

Fluoresene quantum yield

0.93

Extinction Coefficient

74000

CF260

0.22

CF280

0.17

6066-82-6
3301-79-9
92557-81-8
Synthesis of 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER from N-Hydroxysuccinimide and 6-Carboxyfluorescein

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 206)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Scibiotron Pharmaceutical Co., Ltd
+86-16621589600 contact@scibiotron.com China 5369 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13444 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5743 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Xi'an Yutbon Pharmaceutical Technology Co., Ltd
029-81140587 +8618717328141 sales@yutbon.com China 454 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58

View Lastest Price from 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-FAM SE pictures 2025-09-11 6-FAM SE
92557-81-8
US $43.00-143.00 / mg 98.23% 10g TargetMol Chemicals Inc.
6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER pictures 2020-01-09 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER
92557-81-8
US $2.00 / KG 1g 98%min ask Career Henan Chemical Co
  • 6-FAM SE pictures
  • 6-FAM SE
    92557-81-8
  • US $43.00-143.00 / mg
  • 98.23%
  • TargetMol Chemicals Inc.

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER Spectrum

6-CARBOXYFLUORESCEIN SUCCINIMIDE ESTER 6-CARBOXYFLUORESCEIN, SUCCINIMIDYL ESTER 6-CARBOXYFLUORESCEIN-NHS 6-CARBOXYFLUORESCEIN-N-HYDROXYSUCCINIMIDE ESTER 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER 6-CARBOXYFLUORESCEIN, SUCCINIMIDYL*ESTER (SINGLE IS 6-CARBOXYFLUORESCEIN,SUCCINIMIDYL ESTER,6-FAM,SE 98% 6-CARBOXYFLUORESCEIN N-HYDROXYSUCCINIMIDE 6-Carboxyfluorescein N-succinimidyl ester, 6-FAM, SE 6-FAM SE, 6-CF SE 1-[[3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]oxy]-2,5-pyrrolidinedione Fluorescein-6-carboxylic Acid CarboxyfluoresceinN-hydroxysucciniMideeste 6-FAM-SEor6-FAM-NHS 6-FAM-NHS 6-FAM, SE 6-CARBOXYFLUORESCEIN SE 6-CarboxyfluoresceinN-succinimidyl ester≥ 90% (HPLC, 254 nm) 6-FAM, SE [6-Carboxyfluorescein, succinimidyl ester] *CAS 92557-81-8* -xanthene]-6-carboxylate 6-FAM, SE [6-Carboxyfluorescein, succinimidyl ester 6-Carboxyfluorescein N-hydroxysuccinimide ester, 6-FAM-NHS Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-dihydroxy-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester 2,5-dioxopyrrolidin-1-yl 3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylate 5/6-FAM-OSu 6-FAM SE,6-FAM-NHS,6-Carboxyfluorescein N-hydroxysuccinimide ester 6-FAM-OSu(6-carboxyfluoresceinSE) 6-Carboxyfluorescein N-hydroxysuccinimide ester, Fluorescent labeling reagent 6-FAM SE, 10 mM in DMSO 6-FAM, SE [6-Carboxyfluorescein, SE] 6-Carboxyfluoresceinsuccinimidylether 6-FAM SE (Green) 92557-81-8 C25H15NO9 BioChemical Biochemicals and Reagents Detection Fluorescent Probes, Labels, Particles and Stains Fluorescent Labels Fluorescein and Derivatives marker Aromatics Fluorescent Labels & Indicators Heterocycles FLUOROPHORES FAM