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ChemicalBook >> CAS DataBase List >>4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile

4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile

4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile Structure
4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile structure
CAS No.
871814-52-7
Chemical Name:
4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile
Synonyms
libvatrep;Vanilloid receptor antagonist 1;Vanilloid receptor antagonist 1, 10 mM in DMSO;4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile;4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile;Benzonitrile, 4-[7-hydroxy-2-(1-methylethyl)-4-oxo-3(4H)-quinazolinyl]-;TRP Channel,inhibit,Vanilloid receptor antagonist1,Vanilloid receptor antagonist 1,Vanilloid receptor antagonist-1,Inhibitor,Transient receptor potential channels
CBNumber:
CB93693095
Molecular Formula:
C18H15N3O2
Molecular Weight:
305.33
MDL Number:
MFCD18711490
MOL File:
871814-52-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:56:27
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4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile Properties

Boiling point 551.5±60.0 °C(Predicted)
Density 1.26±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (327.51 mM; Need ultrasonic)|Methanol : 17.86 mg/mL (58.49 mM; ultrasonic and warming and heat to 60°C)
form Solid
pka 6+-.0.20(Predicted)
color White to light yellow
FDA UNII 6W8B801TZM
UNSPSC Code 12352200
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302,H315,H319
Precautionary statements  P264-P280-P301+P312-P302+P352-P305+P351+P338-P332+P313

4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 51362 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE 97% 871814-52-7 50MG $1500 2026-04-30 Buy
AstaTech 51362 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE 97% 871814-52-7 0.25G $1980 2026-04-30 Buy
AstaTech 51362 4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE 97% 871814-52-7 1G $2340 2026-04-30 Buy
Biosynth WJB81452 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile 871814-52-7 500mg $1140 2026-06-05 Buy
ChemScene CS-0064882 Libvatrep 99.54% 871814-52-7 5mg $325 2026-06-04 Buy
Product number Packaging Price Buy
51362 50MG $1500 Buy
51362 0.25G $1980 Buy
51362 1G $2340 Buy
WJB81452 500mg $1140 Buy
CS-0064882 5mg $325 Buy

4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile Chemical Properties, Uses, Production

Uses

Vanilloid receptor antagonist 1 is a potent vanilloid receptor TRPV1 antagonist extracted from patent US8349852B2, compound B8[1].

IC 50

TRPV1

References

[1] Weichun Chen, et al. Quinazolinone derivatives useful as vanilloid antagonists. US8349852B2.

4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile Suppliers

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Hangzhou FuRun Pharmaceutical Technology Co., Ltd 15658004993 1900830611@qq.com China 980 58
NewCan Biotech Limited +86-0571-86912261 +86-15658003402 sales@newcanbio.com China 1982 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Supplier Advantage
Shanghai Rechem science Co., Ltd. 58
Shanghai SuperLan Chemcial Technique Centre 58
Amadis Chemical Company Limited 58
TargetMol Chemicals Inc. 58
Hangzhou FuRun Pharmaceutical Technology Co., Ltd 58
NewCan Biotech Limited 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Beijing Boorsen Biotechnology Co., Ltd 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

View Latest Price from 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Vanilloid receptor antagonist 1 pictures 2026-05-30 Vanilloid receptor antagonist 1
871814-52-7
 $60.00-223.00 98.77% 10g TargetMol Chemicals Inc.

4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile Spectrum

4-(7-HYDROXY-2-ISOPROPYL-4-OXOQUINAZOLIN-3(4H)-YL)BENZONITRILE(871814-52-7)1HNMR

871814-52-7 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) Related Search:

2-Hydroxy-8,9-dihydro-6H-pyrido[2,1-b]quinazolin-11(7H)-one 2-hydroxy-7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one hydrochloride 4(3H)-Quinazolinone, 3-(4-methoxyphenyl)-2-methyl- 7-Hydroxy-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile
CAPSAZEPINE

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Benzonitrile, 4-[7-hydroxy-2-(1-methylethyl)-4-oxo-3(4H)-quinazolinyl]- TRP Channel,inhibit,Vanilloid receptor antagonist1,Vanilloid receptor antagonist 1,Vanilloid receptor antagonist-1,Inhibitor,Transient receptor potential channels Vanilloid receptor antagonist 1, 10 mM in DMSO 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile libvatrep Vanilloid receptor antagonist 1 4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile 871814-52-7