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ChemicalBook >> CAS DataBase List >>4-BROMO-2-METHYL-1-NITROBENZENE

4-BROMO-2-METHYL-1-NITROBENZENE

4-BROMO-2-METHYL-1-NITROBENZENE Structure
4-BROMO-2-METHYL-1-NITROBENZENE structure
CAS No.
52414-98-9
Chemical Name:
4-BROMO-2-METHYL-1-NITROBENZENE
Synonyms
3-Bromo-6-nitrotoluene;5-Bromo-2-nitrotoluene 98%;2-Methyl-4-bromonitrobenzene;4-BroMo-2-Methylnitrobenzene;4-Bromo-6-methylnitrobenzene;5-Bromo-1-methyl-2-nitrobenzene;4-BROMO-2-METHYL-1-NITROBENZENE;Benzene,4-broMo-2-Methyl-1-nitro-;2-(3-bromo-2-nitrophenyl)acetonitrile;4-Bromo-2-methyl-1-nitrobenzene, 4-Bromo-2-methylnitrobenzene
CBNumber:
CB9370708
Molecular Formula:
C7H6BrNO2
Molecular Weight:
216.03
MDL Number:
MFCD00137824
MOL File:
52414-98-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 05:56:31
Product description Number Pack Size Price
5-Bromo-2-nitrotoluene 98% OR60239 1g $21
5-Bromo-2-nitrotoluene 98% AS25238 5g $23
5-Bromo-2-nitrotoluene 98% OR60239 5g $24
5-Bromo-2-nitrotoluene 98% AS25238 25g $77
5-Bromo-2-nitrotoluene 98% OR60239 25g $39
More product size
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4-BROMO-2-METHYL-1-NITROBENZENE Properties

Melting point 53-55℃
Boiling point 265℃
Density 1.615
refractive index 1.6120 (estimate)
Flash point 114℃
storage temp. Sealed in dry,Room Temperature
Appearance White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280
HS Code  2929900090

4-BROMO-2-METHYL-1-NITROBENZENE price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR60239 5-Bromo-2-nitrotoluene 98% 52414-98-9 1g $21 2026-06-04 Buy
Activate Scientific AS25238 5-Bromo-2-nitrotoluene 98% 52414-98-9 5g $23 2026-06-04 Buy
Apolloscientific OR60239 5-Bromo-2-nitrotoluene 98% 52414-98-9 5g $24 2026-06-04 Buy
Activate Scientific AS25238 5-Bromo-2-nitrotoluene 98% 52414-98-9 25g $77 2026-06-04 Buy
Apolloscientific OR60239 5-Bromo-2-nitrotoluene 98% 52414-98-9 25g $39 2026-06-04 Buy
Product number Packaging Price Buy
OR60239 1g $21 Buy
AS25238 5g $23 Buy
OR60239 5g $24 Buy
AS25238 25g $77 Buy
OR60239 25g $39 Buy

4-BROMO-2-METHYL-1-NITROBENZENE Chemical Properties,Uses,Production

Uses

5-Bromo-2-nitrotoluene is used the synthesis of biphenylamide derivatives as Hsp90 C-terminal inhibitor for the treatment of cancer and neurodegenerative diseases.

Synthesis

4-BROMO-2-METHYLANILINE

583-75-5

4-BROMO-2-METHYL-1-NITROBENZENE

52414-98-9

General procedure for the synthesis of 4-bromo-2-methyl-1-nitrobenzene from 2-methyl-4-bromoaniline: Step 1: Synthesis of 4-bromo-2-methyl-1-nitrobenzene (193) H2O2 (3.95 mL, 64±5 mmol) was dissolved in DCM (320 mL) at 0°C, cooled and TFAA (10.93 mL, 77 mmol) was added and the mixture was stirred for 5 min at this temperature. The ice bath was then removed, a reflux condenser was installed, and a solution of 4-bromo-2-methylaniline (3 g, 16.12 mmol) in DCM (6.4 mL) was added slowly and dropwise over about 30 minutes. The reaction mixture was heated to reflux for 1 h. After cooling, the reaction mixture was washed sequentially with 30 mL of water and 30 mL of saturated NaHCO3 solution, and the organic layer was dried with MgSO4 and concentrated in vacuum. The crude product was purified by flash column chromatography to give 193 (2.57 g, 11.9 mmol, 74% yield). 1H NMR (CDCl3) δ (ppm): 7.88 (d, J = 8.6 Hz, 1H), 7.53 (d, J = 2.2 Hz, 1H), 7.49 (dd, J = 8.6, 2.2 Hz, 1H), 2.60 (s, 3H).

References

[1] Patent: WO2008/104077, 2008, A1. Location in patent: Page/Page column 122
[2] Journal of Organic Chemistry, 1955, vol. 20, p. 1458
[3] Patent: US4287201, 1981, A

4-BROMO-2-METHYL-1-NITROBENZENE Preparation Products And Raw materials

Raw materials

3-Methyl-4-nitroaniline 4-BROMO-2-METHYLANILINE Trifluoroacetic anhydride Hydrogen peroxide Dichloromethane

Preparation Products

4-bromo-2-(bromomethyl)-1-nitrobenzene

4-BROMO-2-METHYL-1-NITROBENZENE Suppliers

Global( 129)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20121 58
Fluoropharm Co., Ltd. 		+86-0571-85586753 +86-13336034509 sales@fluoropharm.com China 1445 60
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49979 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 9563 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14304 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Fluoropharm Co., Ltd. 		60
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Win-Win chemical CO., Limited 		58

View Lastest Price from 4-BROMO-2-METHYL-1-NITROBENZENE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-BROMO-2-METHYL-1-NITROBENZENE pictures 2026-07-09 4-BROMO-2-METHYL-1-NITROBENZENE
52414-98-9
 $1.00-80.00 1KG 99% Henan Fengda Chemical Co., Ltd
4-BROMO-2-METHYL-1-NITROBENZENE pictures 2020-01-09 4-BROMO-2-METHYL-1-NITROBENZENE
52414-98-9
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

4-BROMO-2-METHYL-1-NITROBENZENE Spectrum

4-BROMO-2-METHYL-1-NITROBENZENE(52414-98-9)1HNMR4-BROMO-2-METHYL-1-NITROBENZENE(52414-98-9)FT-IR

52414-98-9(4-BROMO-2-METHYL-1-NITROBENZENE)Related Search:

2-NITRO 5-BROMO-BENZALDEHYDE 4-BROMO-2-METHYL-1-NITROBENZENE 5-BROMO-2-NITRO-BENZOIC ACID 5-Bromo-2-nitrobenzotrifluoride 1-Bromo-2-methyl-5-nitrobenzene,2-BROMO-1-METHYL-4-NITROBENZENE,3-Bromo-4-methyl-1-nitrobenzene
2,6-DIBROMO-4-NITROTOLUENE 1-Bromo-4-methyl-2-nitrobenzene 2-BROMO-5-NITROTOLUENE 3-BROMO-2-NITROTOLUENE 5-BROMO-3-METHYL-1-NITROBENZENE,1-Bromo-3-methyl-5-nitrobenzene 98%,3-BROMO-5-NITROTOLUENE (5-BROMO-3-METHYL-1-NITROBENZENE),1-BROMO-3-METHYL-5-NITROBENZENE
4-Bromo-2-nitrotoluene 1-BROMO-2-METHYL-3-NITROBENZENE 1-Bromo-2-methyl-6-nitrobenzene 3,5-DIBROMO-2-NITRO-BENZOIC ACID 5-BROMO-2,4-DINITROTOLUENE
3,5-DIBROMO-2,6-DINITROBENZOIC ACID 1-bromo-2,5-dimethyl-4-nitrobenzene 5-Bromo-2-nitrophenylacetic acid

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4-BROMO-2-METHYL-1-NITROBENZENE 3-Bromo-6-nitrotoluene 4-Bromo-6-methylnitrobenzene 5-Bromo-1-methyl-2-nitrobenzene 4-Bromo-2-methyl-1-nitrobenzene, 4-Bromo-2-methylnitrobenzene 4-BroMo-2-Methylnitrobenzene Benzene,4-broMo-2-Methyl-1-nitro- 5-Bromo-2-nitrotoluene 98% 2-Methyl-4-bromonitrobenzene 2-(3-bromo-2-nitrophenyl)acetonitrile 52414-98-9