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2,3-Diethyl-5-methylpyrazine

2,3-Diethyl-5-methylpyrazine Structure
2,3-Diethyl-5-methylpyrazine structure
CAS No.
18138-04-0
Chemical Name:
2,3-Diethyl-5-methylpyrazine
Synonyms
Pyrazine, 2,3-diethyl-5-methyl-;FEMA 3336;FEMA NUMBER 3336;hazelnut pyrazine;2,3-Diethyl-5-Methyl;Diethyl-5-Methylpyraz;LABOTEST-BB LT00453041;2.3.5.6-four Methylpyrazine;5-Methyl-2,3-diethylpyrazine;2,3-diethyl-5-methyl-pyrazin
CBNumber:
CB9375970
Molecular Formula:
C9H14N2
Molecular Weight:
150.22
MDL Number:
MFCD00009635
MOL File:
18138-04-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 06:02:03
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2,3-Diethyl-5-methylpyrazine Properties

Boiling point 95 °C (20 mmHg)
Density 0.949 g/mL at 25 °C (lit.)
refractive index n20/D 1.498(lit.)
FEMA 3336 | 2,3-DIETHYL-5-METHYLPYRAZINE
FLAVIS Number 14.056 | 2,3-Diethyl-5-methylpyrazine
Flash point 176 °F
storage temp. 2-8°C
solubility Chloroform, Methanol
pka 2+-.0.10(Predicted)
color Clear Colourless
Specific Gravity 0.950.949
Odor at 0.10 % in dipropylene glycol. musty nut skin earthy roasted hazelnut toasted potato dusty foliage vegetable
Odor Type musty
biological source synthetic
Water Solubility SLIGHTLY SOLUBLE
JECFA Number 777
Henry's Law Constant 8.1×10-1 mol/(m3Pa) at 25℃, Roberts and Pollien (1997)
Major Application flavors and fragrances
InChI 1S/C9H14N2/c1-4-8-9(5-2)11-7(3)6-10-8/h6H,4-5H2,1-3H3
InChIKey PSINWXIDJYEXLO-UHFFFAOYSA-N
SMILES CCc1ncc(C)nc1CC
LogP 2.16
CAS DataBase Reference 18138-04-0(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 2,3-DIETHYL-5-METHYLPYRAZINE
FDA UNII 530763R0AP
NIST Chemistry Reference Pyrazine, 2,3-diethyl-5-methyl-(18138-04-0)
EPA Substance Registry System Pyrazine, 2,3-diethyl-5-methyl- (18138-04-0)
UNSPSC Code 85151701
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
RIDADR  NA 1993 / PGIII
WGK Germany  3
TSCA  TSCA listed
HazardClass  3
PackingGroup  III
HS Code  29339900
Storage Class 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
NFPA 704
2
0 0

2,3-Diethyl-5-methylpyrazine price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W333603 2,3-Diethyl-5-methylpyrazine 99%, FG 18138-04-0 1 each $58 2026-04-30 Buy
Sigma-Aldrich W333603 2,3-Diethyl-5-methylpyrazine 99%, FG 18138-04-0 100g $187 2026-04-30 Buy
Sigma-Aldrich W333603 2,3-Diethyl-5-methylpyrazine 99%, FG 18138-04-0 1kg $1340 2026-04-30 Buy
Sigma-Aldrich 293814 2,3-Diethyl-5-methylpyrazine 99% 18138-04-0 5g $30.4 2026-04-30 Buy
Sigma-Aldrich W333603 2,3-Diethyl-5-methylpyrazine 99%, FG 18138-04-0 1 unit $56.3 2025-07-31 Buy
Product number Packaging Price Buy
W333603 1 each $58 Buy
W333603 100g $187 Buy
W333603 1kg $1340 Buy
293814 5g $30.4 Buy
W333603 1 unit $56.3 Buy

2,3-Diethyl-5-methylpyrazine Chemical Properties, Uses, Production

Chemical Properties

CLEAR LIGHT YELLOW LIQUID

Chemical Properties

2,3-Diethyl-5-methylpyrazine has a nutty, roasted, vegetable aroma.

Occurrence

Reported to be present in coffee, filberts, potato products, Parmesan cheese, chicken, beef, pork, cocoa, peanuts, popcorn, sesame seed and corn tortillas.

Uses

2,3-Diethyl-5-methylpyrazine is a volatile compound found in food such as almonds and swiss cheese.

Preparation

By condensation of 3,4-hexanedione with propylene diamine.

Definition

ChEBI: 2,3-Diethyl-5-methylpyrazine is a member of pyrazines.

Aroma threshold values

Detection: 0.09 to 1 ppb

Taste threshold values

Taste characteristics at 2.5 ppm: musty, toasted; nutty, potato, cocoa, earthy and dirty.

General Description

2,3-Diethyl-5-methylpyrazine has been identified as a potent odorant in coffee sample and has been evaluated by gas chromatography-olfactometry of decreasing headspace samples.

2,3-Diethyl-5-methylpyrazine Preparation Products And Raw materials

Raw materials

1,2-Diaminopropane 3,4-Hexanedione

Preparation Products

Pyrazine

2,3-Diethyl-5-methylpyrazine Suppliers

Global Suppliers ( 276)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
jiliang chemicals 21-62165282 bidingchem@163.com China 1395 60
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
future industrial shanghai co., ltd 65
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Capot Chemical Co., Ltd 66
Shanghai Longsheng chemical Co.,Ltd. 59
Shanghai Hanhong Scientific Co.,Ltd. 64
jiliang chemicals 60

View Latest Price from 2,3-Diethyl-5-methylpyrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3-Diethyl-5-methylpyrazine pictures 2026-09-02 2,3-Diethyl-5-methylpyrazine
18138-04-0
 $1.20-36.00 1kg 99% Henan Fengda Chemical Co., Ltd
2,3-Diethyl-5-methylpyrazine pictures 2026-06-30 2,3-Diethyl-5-methylpyrazine
18138-04-0
 1KG 95.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2 3-Diethyl-5-Methylpyrazine pictures 2026-05-28 2 3-Diethyl-5-Methylpyrazine
18138-04-0
 $2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD

2,3-Diethyl-5-methylpyrazine Spectrum

2,3-Diethyl-5-methylpyrazine(18138-04-0)MS2,3-Diethyl-5-methylpyrazine(18138-04-0)1HNMR2,3-Diethyl-5-methylpyrazine(18138-04-0)13CNMR2,3-Diethyl-5-methylpyrazine(18138-04-0)IR12,3-Diethyl-5-methylpyrazine(18138-04-0)Raman

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2,3-diethyl-5-methyl-pyrazin 5-Methyl-2,3-diethylpyrazine LABOTEST-BB LT00453041 FEMA NUMBER 3336 2,3-DIETHYL-5-METHYLPYRAZINE 2,3-DIETHYL-6-METHYLPYRAZINE 2-METHYL-5,6-DIETHYLPYRAZINE 2 3-DIETHYL-5-METHYLPYRAZINE 97+% 2,3-Diethyl-5-methylpyrazine, 98+% Pyrazine, 2,3-diethyl-5-methyl- (8CI,9CI) diethylmethylpyrazine,2,3-diethyl-5-methylpyrazine 2.3-Dimethyl-5-Methyl Pyrazine 2,3-Diethyl-5-methylpyrazine,99% 2,3-Diethyl-5-Methyl 2.3.5.6-four Methylpyrazine Diethyl-5-Methylpyraz 2,3-Diethyl-5-methylpyrazine> 2,3-Diethyl-5-methylpyrazine USP/EP/BP hazelnut pyrazine 2,3-Diethyl-5-methylpyrazine with high purity CAS 18138-04-0 2.3-Dimethy-5-methyl pryazine Food additive in Chocolate 2,3-Diethyl-5-methylpyrazine 18138-04-0 FEMA 3336 Pyrazine, 2,3-diethyl-5-methyl- 18138-04-0 18138-04 Building Blocks Heterocyclic Building Blocks Mono- & Polyalkylpyrazines Pyrazines Building Blocks Chemical Synthesis Heterocyclic Building Blocks Alphabetical Listings C-D Flavors and Fragrances Building Blocks Heterocyclic Building Blocks PIPERIDINE Pyrazine Heterocyclic Compounds Mono- & Polyalkylpyrazines Pyrazines pyrazine Flavor