Methyl indole-3-carboxylate
- CAS No.
- 942-24-5
- Chemical Name:
- Methyl indole-3-carboxylate
- Synonyms
- METHYL 1H-INDOLE-3-CARBOXYLATE;methyl indoline-3-carboxylate;3-Methoxycarbonylindole;Methyl 3-indolecarboxylate;INDOLE-3-CARBOXYLIC ACID METHYL ESTER;1H-INDOLE-3-CARBOXYLIC ACID METHYL ESTER;RARECHEM AH BS 0112;3-Carbomethoxyindole;Oxiracetam Impurity 38;3-indole,Methyl forMate
- CBNumber:
- CB9385281
- Molecular Formula:
- C10H9NO2
- Molecular Weight:
- 175.18
- MDL Number:
- MFCD00189407
- MOL File:
- 942-24-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 149-152 °C (lit.) |
|---|---|
| Boiling point | 306.47°C (rough estimate) |
| Density | 1.1999 (rough estimate) |
| refractive index | 1.5060 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 15.42±0.30(Predicted) |
| color | Light Pink |
| Water Solubility | Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water. |
| BRN | 142023 |
| InChI | InChI=1S/C10H9NO2/c1-13-10(12)8-6-11-9-5-3-2-4-7(8)9/h2-6,11H,1H3 |
| InChIKey | QXAUTQFAWKKNLM-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2)C(C(OC)=O)=C1 |
| CAS DataBase Reference | 942-24-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H402 | |||||||||
| Precautionary statements | P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Methyl indole-3-carboxylate price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 395307 | Methyl indole-3-carboxylate 99% | 942-24-5 | 25g | $78.5 | 2023-06-20 | Buy |
| TCI Chemical | I0491 | Methyl Indole-3-carboxylate >98.0%(GC) | 942-24-5 | 25g | $31 | 2026-04-30 | Buy |
| TCI Chemical | I0491 | Methyl Indole-3-carboxylate >98.0%(GC) | 942-24-5 | 500g | $330 | 2026-04-30 | Buy |
| TRC | TRC-M313520-5G | Methyl indole-3-carboxylate | 942-24-5 | 5g | $78 | 2026-06-03 | Buy |
| TRC | TRC-M313520-1G | Methyl indole-3-carboxylate | 942-24-5 | 1g | $68 | 2026-06-03 | Buy |
Methyl indole-3-carboxylate Chemical Properties,Uses,Production
Chemical Properties
light brown amorphous powder
Uses
Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II.
Uses
Reactant for preparation of:
- Nitric oxide synthase (nNOS) inhibitorS
- Protein kinase c alpha (PKCα) inhibitors
- Inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents
- Kinase insert domain receptor (KDR) inhibitors
- Organocatalysts for the anti-Mannich reaction
- Very late antigen-4 (VLA-4) antagonists
- Inhibitors of Human 5-Lipoxygenase
- Serotonin 5-HT4 receptor antagonists
- Hyaluronidase inhibitors
Reactant for:
- Enantioselective Meerwein-Eschenmoser Claisen rearrangement reactions
Definition
ChEBI: Methyl indole-3-carboxylate is the methyl ester of indole-3-carboxylic acid. It has a role as a metabolite. It is a member of indoles and a methyl ester. It is functionally related to an indole-3-carboxylic acid.
General Description
Methyl indole-3-carboxylate (3-Methoxycarbonylindole, 3-Carbomethoxyindole, Methyl indolyl-3-carboxylate) has been extracted from the marine Streptomyces sp. 060524. Its crystal structure indicates the presence of inter-molecular N-H…O hydrogen bond. It is also obtained during the isolation of sorazinones A and B from Sorangium cellulosum strain Soce895. It undergoes regioselective dibromination with bromine in acetic acid to afford methyl 5,6-dibromoindole-3-carboxylate.
Methyl indole-3-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Roche Technology Development Co., Ltd., | 18986168071; 18986168071 | 18986168071@163.com | China | 95 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Lastest Price from Methyl indole-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Methyl indole-3-carboxylate
942-24-5
|
$1.00 | 300g | 99.8% | 20 TONS | .GZ HONESTCHEM CO.,LTD | |
 |
2026-05-11 | Methyl indole-3-carboxylate
942-24-5
|
$29.00 | 99.41% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-06-27 | Methyl indole-3-carboxylate
942-24-5
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Methyl indole-3-carboxylate
942-24-5
- $1.00
- 99.8%
- .GZ HONESTCHEM CO.,LTD
-
- Methyl indole-3-carboxylate
942-24-5
- $29.00
- 99.41%
- TargetMol Chemicals Inc.
-
- Methyl indole-3-carboxylate
942-24-5
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
