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Menthofuran

Menthofuran structure

CAS No.: 494-90-6

Chemical Name:: Menthofuran

Synonyms: Menthofurane;FEMA 3235;4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN;Benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl-;MENTHOFURA;Menthofuran;MENTHOFURAN(SG);Menthofuran,95%;UNII:LK024V9U3C;MENTHOFURAN WITH GC

CBNumber:: CB9407301

Molecular Formula:: C10H14O

Molecular Weight:: 150.22

MDL Number:: MFCD00041851

MOL File:: 494-90-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:56:28

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Menthofuran Properties

Melting point	86°C
Boiling point	80-82 °C13 mm Hg(lit.)
Density	0.97 g/mL at 25 °C(lit.)
refractive index	n20/D 1.485(lit.)
FEMA	3235 \| 4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN
Flash point	168 °F
storage temp.	Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Liquid
color	Clear light yellow
Odor	at 1.00 % in dipropylene glycol. pungent musty nutty earthy coffee
Odor Type	musty
optical activity	[α]25/D +90°, c = 10 in methanol
JECFA Number	758
Stability	Not stable in solution
Cosmetics Ingredients Functions	PERFUMING
LogP	4.02
CAS DataBase Reference	494-90-6(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)	4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN
FDA UNII	LK024V9U3C
EPA Substance Registry System	Benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl- (494-90-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Hazard statements

H227

Precautionary statements

P210e-P280a-P370+P378a-P403+P235-P501a

Safety Statements

24/25

WGK Germany

RTECS

DF7995750

TSCA

TSCA listed

HS Code

29329990

NFPA 704

	2
1		0

Menthofuran price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	W323500	4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran ≥95%	494-90-6	sample	$54.6	2023-06-20	Buy
Biosynth	FD132661	3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran	494-90-6	10g	$196.4	2026-06-04	Buy
Biosynth	FD132661	3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran	494-90-6	25g	$314.25	2026-06-04	Buy
Biosynth	FD132661	3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran	494-90-6	50g	$393	2026-06-04	Buy
Biosynth	FD132661	3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran	494-90-6	100g	$471	2026-06-04	Buy

Product number	Packaging	Price	Buy
W323500	sample	$54.6	Buy
FD132661	10g	$196.4	Buy
FD132661	25g	$314.25	Buy
FD132661	50g	$393	Buy
FD132661	100g	$471	Buy

Menthofuran Chemical Properties, Uses, Production

Odor

Sweet, haylike-minty odor, sometimes referred to as "Lactone"-odor. Moderate to poor tenacity. The initial impression is that of a very pungent and sharp odor. The taste - in dilutions lower than 10 ppm -is slightly bitter, almost tarry and not very pleasant.

Chemical Properties

CLEAR LIGHT YELLOW LIQUID

Chemical Properties

Menthofuran occurs as the (+) isomer, in peppermint essential oils. It is a colorless liquid with a minty odor.

Chemical Properties

4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran has an odor very similar to that of menthol.

Occurrence

Reported found in peppermint oil, corn mint oil, spearmint oil, Scotch spearmint oil, pennyroyal oil and other Mentha oils and buchu oil.

Uses

Menthofuran is a toxin found in vairety of essential oils and is believed to be the compound responsible for the potentially fatal effects of Pennyroyal. Menthofuran is known to produce hepatotoxic intermediates via oxidation process.

Definition

ChEBI: Menthofuran is a monoterpenoid that is 4,5,6,7-tetrahydro-1-benzofuran substituted by methyl groups at positions 3 and 6. It has a role as a nematicide and a plant metabolite. It is a member of 1-benzofurans and a monoterpenoid.

Preparation

(+)-Menthofuran [17957-94-7] is isolated fromMentha oils or is prepared synthetically, for example, by treatment of (+)-pulegone with fuming sulfuric acid in acetic anhydride and pyrolysis of the resulting sultone.

Taste threshold values

Taste characteristics at 10 ppm: musty, nutty, coffee, raw and legume

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 2442, 1983 DOI: 10.1021/jo00162a037

Synthesis

By thermal decomposition of the sulfone of 3-hydroxy-3,8(9)-methadiene-9-sulfonic acid; the latter is obtained by sulfonapulegone in acetic anhydride.

Menthofuran synthesis

Synthesis of Menthofuran from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

Menthofuran Preparation Products And Raw materials

Raw materials

Benzofuran,3,6-dimethyl-

Preparation Products

Menthofuran Suppliers

Global Suppliers ( 191)

Supplier	Tel	Email	Country	ProdList	Advantage
Anhui Yunhefei Spice Co., Ltd.	15755158983 15755158983	yunhefei@foxmail.com	China	43	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Maya High Purity Chemicals	+86 (573) 82222445 (0)18006601000 452520369	sales@maya-r.com	China	11693	57
Thermo Fisher Scientific	800-810-5118	cnchemical@thermofisher.com	China	17752	75
Beijing innoChem Science & Technology Co.,Ltd.	400-810-7969 010-59572699	ningzi.li@inno-chem.com.cn	China	6122	55
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	22497	55

Supplier	Advantage
Anhui Yunhefei Spice Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
Energy Chemical	61
Chemsky（shanghai）International Co.,Ltd.	50
Maya High Purity Chemicals	57
Thermo Fisher Scientific	75
Beijing innoChem Science & Technology Co.,Ltd.	55
9ding chemical ( Shanghai) Limited	55

View Latest Price from Menthofuran manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-07	MENTHOFURAN 494-90-6	$17.00-30.00	1KG	99%	200000KG	Shaanxi Dideu Medichem Co. Ltd
2026-06-30	MENTHOFURAN 494-90-6		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2026-06-11	Menthofuran 494-90-6	$30.00		90.62%	10g	TargetMol Chemicals Inc.

MENTHOFURAN
494-90-6
$17.00-30.00
99%
Shaanxi Dideu Medichem Co. Ltd

MENTHOFURAN
494-90-6
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

Menthofuran
494-90-6
$30.00
90.62%
TargetMol Chemicals Inc.

Menthofuran Spectrum

MENTHOFURAN(494-90-6)¹HNMR MENTHOFURAN(494-90-6)FT-IR MENTHOFURAN(494-90-6)IR

494-90-6 (Menthofuran) Related Search:

Salicylic acid Geneticin Ethanol Citric acid FURFURYL ALCOHOL RESIN

Carbofuran Furazolidone Edible essence 2(4H)-Benzofuranone, 5,6-dihydro-3,6-dimethyl-, (6R)- Menthofuran

(+)-Menthofuran 3,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-benzofuran-2-carboxylic acid 3-Acetyl-2,6,6-trimethyl-5,6,7-trihydrooxainden-4-one menthofuran synthase 6,6-Dimethyl-4-oxo-4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid

(2,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-benzofuran-3-yl)-acetic acid 4-Hydroxy-3,6,6-trimethyl-4,5,6,7-tetrahydro-1-benzofuran-2-carboxylic acid Menthofuran(4,5,6,7-tetrahydro-3,6-dimethylbenzofuran)

1of4

3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran 3,9-Epoxy-p-mentha-3,8-diene 4,5,6,7-tetrahydro-3,6-dimethyl-benzofura Benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl- p-Mentha-3,8-diene, 3,9-epoxy- 4 5 6 7-TETRAHYDRO-3 6-DIMETHYLBENZOFUR& Menthofuran,95% 3,6-dimethyl-4,5,6,7-tetrahydrobenzofuran MENTHOFURAN(SG) MENTHOFURAN WITH GC MENTHOFURAN, NATURAL (6R)-3,6-Dimethyl-4,5,6,7-tetrahydrobenzofuran (R)-4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran 4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran,Menthofuran Menthofuran, 95% 10GR MENTHOFURA UNII:LK024V9U3C MENTHOFURAN Extra Pure Inhibitor,peppermint oil biosynthesis,inhibit,monoterpene reductase,Menthofuran,Drug Metabolite 4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN FEMA 3235 Menthofurane Menthofuran 494-90-6