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ChemicalBook >> CAS DataBase List >>2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Structure
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile structure
CAS No.
177028-90-9
Chemical Name:
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile
Synonyms
WAY-298592;AChE-IN-27;AChE-IN-27, 10 mM in DMSO;2-Amino-5-oxo-4-(p-tolyl)-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile;2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile;4H,5H-Pyrano[3,2-c][1]benzopyran-3-carbonitrile, 2-amino-4-(4-methylphenyl)-5-oxo-;neurological diseases,alzheimer's disease,WAY 298592,Inhibitor,dementia,myasthenia gravis,Cholinesterase (ChE),inhibit,ataxia,WAY298592
CBNumber:
CB94228740
Molecular Formula:
C20H14N2O3
Molecular Weight:
330.34
MDL Number:
MFCD00565058
MOL File:
177028-90-9.mol
MSDS File:
SDS
Last updated:2026-07-09 12:03:46
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2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Properties

Melting point 255 °C
Boiling point 641.0±55.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (302.72 mM; ultrasonic and warming and heat to 60°C)
pka 3.15±0.40(Predicted)
form Solid
color White to off-white

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0612004 AChE-IN-27 98.27% 177028-90-9 5mg $38 2026-06-04 Buy
ChemScene CS-0612004 AChE-IN-27 98.27% 177028-90-9 10mg $60 2026-06-04 Buy
ChemScene CS-0612004 AChE-IN-27 98.27% 177028-90-9 25mg $119 2026-06-04 Buy
ChemScene CS-0612004 AChE-IN-27 98.27% 177028-90-9 50mg $179 2026-06-04 Buy
ChemScene CS-0612004 AChE-IN-27 98.27% 177028-90-9 100mg $269 2026-06-04 Buy
Product number Packaging Price Buy
CS-0612004 5mg $38 Buy
CS-0612004 10mg $60 Buy
CS-0612004 25mg $119 Buy
CS-0612004 50mg $179 Buy
CS-0612004 100mg $269 Buy

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Chemical Properties, Uses, Production

Uses

AChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 μM). AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis[1].

References

[1] Bouazizi Y, et al. Synthesis of new 3, 4-dihydropyrano [c] chromene derivatives and their evaluation as acetyl cholinesterase inhibitors[J]. European Journal of Chemistry, 2014, 5(3): 457-462.

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Suppliers

Global Suppliers ( 21)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 9780 55
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Supplier Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 60
Tianjin Kailiqi Biotechnology Co., Ltd. 55
TargetMol Chemicals Inc. 58
Zhejiang Huida Biotech Co., LTD 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Beijing Boorsen Biotechnology Co., Ltd 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

View Latest Price from 2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AChE-IN-27 pictures 2026-08-08 AChE-IN-27
177028-90-9
 $53.00-119.00 99.74% 10g TargetMol Chemicals Inc.
  • AChE-IN-27 pictures
  • AChE-IN-27
    177028-90-9
  • $53.00-119.00
  • 99.74%
  • TargetMol Chemicals Inc.

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Spectrum

2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile(177028-90-9)1HNMR

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2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile WAY-298592 neurological diseases,alzheimer's disease,WAY 298592,Inhibitor,dementia,myasthenia gravis,Cholinesterase (ChE),inhibit,ataxia,WAY298592 2-Amino-5-oxo-4-(p-tolyl)-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile 4H,5H-Pyrano[3,2-c][1]benzopyran-3-carbonitrile, 2-amino-4-(4-methylphenyl)-5-oxo- AChE-IN-27 AChE-IN-27, 10 mM in DMSO 177028-90-9