2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile

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2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile manufacturers

  • AChE-IN-27
  • AChE-IN-27 pictures
  • $53.00
  • 2026-08-08
  • CAS:177028-90-9
  • Purity: 99.74%
  • Supply Ability: 10g
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Basic information
Product Name:2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile
Synonyms:2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile;WAY-298592;neurological diseases,alzheimer's disease,WAY 298592,Inhibitor,dementia,myasthenia gravis,Cholinesterase (ChE),inhibit,ataxia,WAY298592;2-Amino-5-oxo-4-(p-tolyl)-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile;4H,5H-Pyrano[3,2-c][1]benzopyran-3-carbonitrile, 2-amino-4-(4-methylphenyl)-5-oxo-;AChE-IN-27;AChE-IN-27, 10 mM in DMSO
CAS:177028-90-9
MF:C20H14N2O3
MW:330.34
EINECS:
Product Categories:
Mol File:177028-90-9.mol
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Structure
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Chemical Properties
Melting point 255 °C
Boiling point 641.0±55.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (302.72 mM; ultrasonic and warming and heat to 60°C)
pka3.15±0.40(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Usage And Synthesis
UsesAChE-IN-27 (compound 8c) is an AChE inhibitor (IC50=0.19 μM). AChE-IN-27 can be used in studies of neurological diseases such as alzheimer's disease, dementia, ataxia and myasthenia gravis[1].
References[1] Bouazizi Y, et al. Synthesis of new 3, 4-dihydropyrano [c] chromene derivatives and their evaluation as acetyl cholinesterase inhibitors[J]. European Journal of Chemistry, 2014, 5(3): 457-462.
2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile Preparation Products And Raw materials
Tag:2-amino-4-(4-methylphenyl)-5-oxo-4H-pyrano[3,2-c]chromene-3-carbonitrile(177028-90-9) Related Product Information
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