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4-Amino-2-nitro-benzoic acid ethyl ester

CAS No.
84228-46-6
Chemical Name:
4-Amino-2-nitro-benzoic acid ethyl ester
Synonyms
ETHYL 4-AMINO-2-NITROBENZOATE;4-Amino-2-nitro-benzoic acid ethyl ester;Benzoic acid, 4-amino-2-nitro-, ethyl ester
CBNumber:
CB9425161
Molecular Formula:
C9H10N2O4
Molecular Weight:
210.19
MDL Number:
MFCD06656140
MOL File:
84228-46-6.mol
MSDS File:
SDS
Last updated:2026-09-12 18:56:28

4-Amino-2-nitro-benzoic acid ethyl ester Properties

storage temp. Keep in dark place,Sealed in dry,Room Temperature

4-Amino-2-nitro-benzoic acid ethyl ester price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 304860 Ethyl 4-amino-2-nitrobenzoate 84228-46-6 250.00mg $39 2026-05-19 Buy
Matrix Scientific 304860 Ethyl 4-amino-2-nitrobenzoate 84228-46-6 1.00g $71 2026-05-19 Buy
Matrix Scientific 304860 Ethyl 4-amino-2-nitrobenzoate 84228-46-6 5.00g $235 2026-05-19 Buy
Synthonix E49743 Ethyl 4-amino-2-nitrobenzoate 95+% 84228-46-6 250mg $100 2026-05-06 Buy
Synthonix E49743 Ethyl 4-amino-2-nitrobenzoate 95+% 84228-46-6 1g $190 2026-05-06 Buy
Product number Packaging Price Buy
304860 250.00mg $39 Buy
304860 1.00g $71 Buy
304860 5.00g $235 Buy
E49743 250mg $100 Buy
E49743 1g $190 Buy

4-Amino-2-nitro-benzoic acid ethyl ester Chemical Properties, Uses, Production

Synthesis

Ethanol

64-17-5

CBI-BB ZERO/006118

21573-29-5

4-AMINO-2-NITRO-BENZOIC ACID ETHYL ESTER

84228-46-6

General steps: 1. dissolve 4-acetamido-2-nitrobenzoic acid (1.80 g, 8.0 mmol) in a mixture of 12 N hydrochloric acid (14 mL) and anhydrous ethanol (10 mL). 2. The reaction mixture was heated to 90-100°C and kept for 5 hours. 3. Upon completion of the reaction, the ethanol is removed by vacuum concentration. 4. The pH of the reaction mixture was adjusted to 4 with 1 N sodium hydroxide solution. 5. The precipitate was collected by filtration to give ethyl 4-amino-2-nitrobenzoate (140 mg, 8% yield). Product characterization data: 1H-NMR (CDCl3): δ 7.61 (d, J = 8.5 Hz, 1H), 6.82 (d, J = 2.1 Hz, 1H), 6.74 (dd, J = 8.5, 2.1 Hz, 1H), 6.52 (bs, 2H), 4.17 (q, J = 7.1 Hz, 2H), 1.21 (t, J = 7.1 Hz, 3H); MS ( DCI) m/e: 211 (MH+).

References

[1] Patent: US5618839, 1997, A
[2] Patent: US5648385, 1997, A

4-Amino-2-nitro-benzoic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzoic acid, 4-amino-2-nitro-, ethyl ester ETHYL 4-AMINO-2-NITROBENZOATE 4-Amino-2-nitro-benzoic acid ethyl ester 84228-46-6 Aromatic Building Blocks Aromatic Esters API intermediates